SARS-CoV-2 immune complex triggers human monocyte necroptosisArticle Published on 2023-02-272024-09-05 Journal: International immunopharmacology [Category] update2024, [키워드] COVD-19 pathogenesis Fcγ receptors MLKL monocyte necroptosis SARS-CoV-2 [DOI] 10.1016/j.intimp.2023.109954 PMC 바로가기 [Article Type] Article
Integrated Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unravels the Influences of SARS-CoV-2 Infections to Cancer PatientsArticle Published on 2022-12-102023-07-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), [키워드] acute respiratory distress Cancer drug molecule Immunity m6A monocyte PPI pulmonary fibrosis SARS-CoV-2 single-cell RNA-seq [DOI] 10.3390/ijms232415698 PMC 바로가기
The mononuclear phagocyte system in hepatocellular carcinomaReview Published on 2022-12-072023-06-13 Journal: World journal of gastroenterology [Category] B형 간염, [키워드] dendritic cell Hepatocellular carcinoma Macrophage monocyte Mononuclear phagocyte system. [DOI] 10.3748/wjg.v28.i45.6345 PMC 바로가기 [Article Type] Review
Clinical features and high-resolution chest computerized tomography findings of children infected by the B.1.617.2 variant of coronavirus disease 2019Article Published on 2022-12-012022-11-16 Journal: Annals of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] absence age analysed analyses B.1.617.2 B.1.617.2 (Delta) variant biochemical Blood Cell Chest Chest CT chest. children China clinical clinical symptom Clinical symptoms collected Computerized tomography Concentration consolidation coronavirus disease corpuscular correlated correlation cough COVID-19 CT CT finding Delta Diagnosis Disease diagnosis disease stage distribution elevated Factor feature Fever Follow-up ground-glass opacity group Haemoglobin High-resolution imaging Infection Laboratory Laboratory tests lymphocyte males Mild monocyte Nanjing no difference pathological change Patient percentage pharyngeal Platelet regression analysis serum alkaline phosphatase significant effect Stage stages statistically significant Subtypes Symptom Symptoms the disease variant Volume [DOI] 10.1080/07853890.2022.2114608 PMC 바로가기
Potential mechanisms of vaccine-induced thrombosisArticle Published on 2022-11-012022-11-15 Journal: European journal of internal medicine [Category] 유전자 메커니즘, 진단, [키워드] activate Ad26.COV2.S Adenovirus administration AdV vector antibodies antibody Autoimmune heparin-induced thrombocytopenia B cell Bacteria BNT162b cerebral venous sinuse ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine characterized clinical conformational change Contact COVID-19 COVID-19 vaccine COVID-19 vaccines described develop Effectiveness elicited events expression Factors Gene therapy heparin-induced thrombocytopenia hexone immune complex immune response Immune thrombocytopenia immunothrombosis IMPROVE induce intrinsic knowledge laboratory feature mechanism monocyte occur PF4 Platelet Platelets Potential proinflammatory Protein receiving resulting Spike protein splice subject syndrome T-cell thrombosis Vaccine Vaccine- induced immune thrombocytopenia and thrombosis. vectors Venous thrombosis viruses [DOI] 10.1016/j.ejim.2022.08.002 PMC 바로가기
Monocyte epigenetics and innate immunity to malaria: yet another level of complexity?article Published on 2022-10-312024-09-01 Journal: International Journal for Parasitology [Category] 말라리아, [키워드] DNA methylation epigenetics Inflammation malaria monocyte Pathogenesis Plasmodium falciparum [Article Type] article
Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatmentarticle Published on 2022-10-312024-09-01 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] Blood Brain cerebral malaria (CM) Chloroquine mice monocyte spleen [Article Type] article
The Peripheral Immune Landscape in a Patient with Myocarditis after the Administration of BNT162b2 mRNA VaccineArticle Published on 2022-10-312022-11-15 Journal: Molecules and cells [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Analysis approved BNT162b2 BNT162b2 mRNA vaccination causes cell clusters change changes in complications coronavirus Differentially expressed genes global public health help IL7R immune increased expression increased risk landscape Messenger RNA monocyte mononuclear cell mRNA myocarditis of BNT162b2 pandemic Pathogenesis Patient PBMC PBMCs peripheral Peripheral blood peripheral blood mononucleear cells reported Research SARS-CoV-2 Sequencing severe acute respiratory syndrome coronavirus 2 single-cell Single-cell RNA sequencing T cell receptor Transcriptome transcriptomic profile vaccinated individual vaccination Vaccine [DOI] 10.14348/molcells.2022.0031 PMC 바로가기
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responsesArticle Published on 2022-10-242022-11-15 Journal: PLoS Pathogens [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] ACE2 activated Activation alleviate Antigen CD169 CD169+ macrophage contribute COVID-19 pathology COVID-19 patients de novo elicited exogenous ACE2 expression expression of SARS-CoV-2 facilitated genomic humans Hyperinflammatory IL-1β IL-6 independent induce Infection innate immune response Macrophage macrophages MDA-5 monocyte myeloid cell Post-mortem primary target cell pro-inflammatory cytokine pro-inflammatory response Remdesivir Replication Restricted RIG-I RNA SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection subgenomic RNA subsequent suppressed the SARS-CoV-2 thought TNFα Treatment viral particle Viral protein Viral RNA [DOI] 10.1371/journal.ppat.1010479 PMC 바로가기
The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosisArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 24 hours activated Activation Apoptosis apoptotic cascade caused Cell cell damage characterized contribute COVID-19 CTLs Cytokines Diabetes Mellitus Diagnosis Diseases ENhance exhibit fungal Fungal infection fungi Hematological malignancies host cell Host immune response host inflammatory response host-pathogen interactions human monocyte human monocytes IL-1β IL-6 increase in individual Infection Inflammatory Inflammatory response inflammatory signaling Interaction invasive killing life-threatening modulation monocyte mortality rate Mucorales Mucormycosis NF-kB Occurrence organ pathogenic phagocyte phagocytosis priming pro-inflammatory cytokine produced progression PRRs receptor receptors regulate secreted signaling pathway spore susceptible synergistic therapy TLR TLR4 TLRs TNF-α Toll-like receptor transcription factor virulent [DOI] 10.3389/fimmu.2022.882921 PMC 바로가기