Omicron BA.1 Mutations in SARS-CoV-2 Spike Lead to Reduced T-Cell Response in Vaccinated and Convalescent IndividualsSARS-CoV-2 스파이크의 Omicron BA.1 돌연변이는 백신 접종 및 회복기 개인의 T-세포 반응 감소로 이어집니다Article Published on 2022-07-192022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] alleles BNT162b2 BNT162b2 vaccine CD4 CD4+ T-cell CD4+ T-cell epitopes cellular immunity circulating cross-reactive cross-reactivity elicited Epitopes escape facilitated help HLA HLA class II HLA class II alleles HLA motif prediction immune Immune escape immunodominant epitope immunodominant epitopes individual infect loss of memory memory monitoring motif mRNA mRNA-based Mutation mutations natural infection Neutralizing antibodies omicron Omicron BA.1 variant predict predicted preserved reactivity response SARS-CoV-2 SARS-CoV-2 immunity selected spike Spike protein spike-protein strain T cell T cells T-cell T-cell epitope T-cell epitopes T-cell Response T-cell responses the spike protein vaccination variant virus variant virus variants [DOI] 10.3390/v14071570 PMC 바로가기 [Article Type] Article
Early human B cell signatures of the primary antibody response to mRNA vaccinationmRNA 백신 접종에 대한 1차 항체 반응의 초기 인간 B 세포 서명Article Published on 2022-07-122022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] Coronavirus, COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome adaptive Adaptive immunity Adults antibodies antibody Antibody Response Antibody titers approach B cell B cells burst Cell cellular cellular response Cohort coronavirus correlated correlation defined determinant dissect dose effective first dose Frequency IgA IgG antibody Immunity immunoglobulin A individuals less magnitude MBC memory B messenger mRNA mRNA vaccination mRNA vaccines mRNA-1273 vaccine mRNA-based phenotype plasmablast Population postvaccination primary antibody protective immunity remained response RNA robust SARS-CoV-2 second dose subsequent sustained vaccination Vaccine while [DOI] 10.1073/pnas.2204607119 PMC 바로가기 [Article Type] Article
Solid cancer patients achieve adequate immunogenicity and low rate of severe adverse events after SARS-CoV-2 vaccination고형암 환자는 SARS-CoV-2 백신 접종 후 적절한 면역원성과 낮은 중증 부작용 발생률 달성Article Published on 2022-07-012022-09-11 Journal: Future Oncology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] A significant reduction active treatment Adverse adverse events anti-SARS-CoV-2 S1 IgG antibody antibody level antibody levels anticancer anticancer treatment cancer patient Cancer patients Complete Course COVID-19 disease event healthy controls Immune checkpoint inhibitor Immune checkpoint inhibitors immunogenicity Mild mRNA mRNA-based mRNA-based vaccination mRNA-based vaccine participant Patient patients Prevent receiving Result SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose Seroconversion seroconversion rate serum severe adverse event severe COVID-19 disease Solid solid cancer therapy Treatment vaccination [DOI] 10.2217/fon-2022-0148 PMC 바로가기 [Article Type] Article
Type 1 Diabetes Mellitus Associated with Nivolumab after Second SARS-CoV-2 Vaccination, Japan일본, 2차 SARS-CoV-2 백신 접종 후 니볼루맙과 관련된 제1형 당뇨병Case Reports Published on 2022-07-012022-09-12 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome adverse events coronavirus coronavirus disease Coronaviruses COVID-19 diabete Diabetes Mellitus immune Immune checkpoint inhibitor incidence Japan mRNA mRNA vaccine mRNA-based nivolumab Patient respiratory infections SARS-CoV-2 SARS-CoV-2 vaccination second second SARS-CoV-2 vaccination severe acute respiratory syndrome coronavirus 2 Type Type 1 diabetes mellitus Vaccines virus zoonoses [DOI] 10.3201/eid2807.220127 PMC 바로가기 [Article Type] Case Reports
Increased antibody response after SARS-CoV-2 mRNA-based vaccination in rituximab-treated patients with previous COVID-19 infection이전 COVID-19 감염이 있는 리툭시맙 치료 환자에서 SARS-CoV-2 mRNA 기반 백신 접종 후 항체 반응 증가Article Published on 2022-06-282022-09-12 Journal: Rheumatology (Oxford, England) [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Antibody Response COVID-19 infection Increased mRNA-based Patient SARS-CoV-2 vaccination [DOI] 10.1093/rheumatology/keac201 PMC 바로가기 [Article Type] Article
Seroprevalence of immunoglobulin G antibodies against SARS-CoV-2 in Cyprus키프로스에서 SARS-CoV-2에 대한 면역글로불린 G 항체의 혈청유병률Article Published on 2022-06-132022-09-12 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Analysis antibody Antibody Response ChAdOx1 nCoV-19 coronavirus disease COVID-19 Cyprus dose elicit Evidence IgG antibody Immunoglobulin individual infected with SARS-CoV-2 Infection infection with SARS-CoV-2 monitoring mRNA-based mRNA-based vaccine pandemic plasma Previous studies produced public health response responses SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 spike protein Seroprevalence single dose the SARS-CoV-2 the vaccine Vaccine virus Zeneca [DOI] 10.1371/journal.pone.0269885 PMC 바로가기 [Article Type] Article
Serologic response to a third dose of an mRNA-based SARS-CoV-2 vaccine in lung transplant recipients폐 이식 환자에서 mRNA 기반 SARS-CoV-2 백신 3차 접종에 대한 혈청학적 반응Article Published on 2022-06-012022-09-12 Journal: Transplant immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome binding complement coronavirus COVID-19 cut-off value develop dose Factor Immune status IMPROVE increased risk Infection lectin pathway lung transplant mRNA-based mRNA-based SARS-CoV-2 vaccine parameters Patient positive Prednisone Previous studies recipient recipients SARS-CoV-2 SARS-CoV-2 vaccine serologic Serologic response serological response serum IgG severe coronavirus disease significantly significantly higher solid organ transplant vaccination vaccination response vaccine dose was measured [DOI] 10.1016/j.trim.2022.101599 PMC 바로가기 [Article Type] Article
Humoral response after a fourth “booster” dose of a Coronavirus disease 2019 vaccine following a 3-dose regimen of mRNA-based vaccination in dialysis patients투석 환자에서 mRNA 기반 백신 3회 접종 후 코로나바이러스 질병 2019 백신의 4차 "부스터" 접종 후 체액 반응Article Published on 2022-06-012022-09-12 Journal: Kidney international [Category] MERS, 진단, [키워드] Coronavirus disease 2019 dialysis dose Humoral response mRNA-based Patient regimen vaccination Vaccine [DOI] 10.1016/j.kint.2022.04.006 PMC 바로가기 [Article Type] Article
Humoral response to mRNA-based COVID-19 vaccine in patients with myeloid malignancies골수성 악성종양 환자에서 mRNA 기반 코로나19 백신에 대한 체액 반응Article Published on 2022-06-012022-09-12 Journal: British Journal of Haematology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute myeloid leukaemia AML Anti-spike Antibody titre appear comparable COVID-19 COVID-19 vaccine disease HCs healthy control humoral Humoral response Infection lymphoid malignancies malignancy MDs mRNA-based mRNA-based COVID-19 vaccine myelodysplastic syndrome. myeloid malignancies myeloid malignancy no significant difference Patient patients risk SARS-CoV-2 SARS-CoV-2 antibody titre SARS-CoV-2 vaccine significantly lower syndrome therapy Treatment vaccination Vaccine were measured [DOI] 10.1111/bjh.18138 PMC 바로가기 [Article Type] Article
BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection?BNT162b2 백신은 타액에서 항체 방출을 유도합니다: 점막 바이러스 보호를 위한 가능한 역할?Article Published on 2022-05-092022-09-11 Journal: EMBO Molecular Medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Administered antibody BNT162b2 BNT162b2 vaccine cleaved Concentration Course Decline effective full-length spike protein IgA IgA antibodies IgG Immunity in viral induce Infection mRNA mRNA-based mRNA-based vaccine mucosal mucosal immunity pathogen Pfizer/BioNTech plasma plasma IgG protease PROTECT Saliva SARS-CoV-2 Spike protein subjects systemically vaccination Viral [DOI] 10.15252/emmm.202115326 PMC 바로가기 [Article Type] Article