The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population
Medicine
[키워드] MUC5B
acute respiratory syndrome
age and sex
aging lung
Analysis
Associate
association
candidate gene
Case-control
case-control study
Cohort
cohorts
comparable
confounding variable
Control
coronavirus
COVID-19
died
Diversity
European
Evidence
expressing
expression level
Frequency
Genotype
GWAS
Hospitalization
ICU
Idiopathic pulmonary fibrosis
innate immune response
Innate immunity
investigated
IPF
Italian
Italy
lung
Lung disease
male
median age
MUC5B
Mucus
non-infectious
Patient
polymorphism
Population
promoter
provide
pulmonary fibrosis
recruited
replicated
Replication
retrospective
risk allele
SARS-CoV-2
severe COVID-19
significantly
significantly lower
Spain
Spanish
trade-off
was performed
was used
while
with COVID-19
[DOI] 10.3389/fmed.2021.668024 PMC 바로가기 [Article Type] Medicine
[DOI] 10.3389/fmed.2021.668024 PMC 바로가기 [Article Type] Medicine