multiple organ – Page 2 – Communicable Diseases Research

System-wide transcriptome damage and tissue identity loss in COVID-19 patients

COVID-19 환자의 시스템 전체 전사체 손상 및 조직 정체성 상실

Article

Published on 2022-01-242022-09-10
Journal: Cell Reports Medicine
[Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

COVID-19 and Sepsis

Article

Published on 2021-12-172022-10-29
Journal: Turkish Journal of Medical Sciences
[Category] COVID-19, SARS,

[키워드] acute phase reactant acute respiratory distress addition affecting alterations ARDS assist association Autopsy Bacterial sepsis Blood cause caused Cell changes chemokine Clinical deterioration coagulation tests component consolidation contributing to Course COVID-19 COVID-19 pandemic COVID-19 pathogenesis COVID-19 patient COVID-19 sepsis CRP Cytokine storm D-dimer demonstrated Diffuse alveolar damage direct viral infection dominant dysregulated immune response endothelial injury explained Faeces feature ferritin Gallbladder hematological hemorrhage histopathological HLH hospitalized patient Hyperactivation hypercoagulability hypercoagulable hyperinflammation immune immune response IMPROVE indicated infiltration inflammatory cell intrinsic Laboratory laboratory parameter limit liver liver function tests lung tissue Lungs macrophages manifestation modulate multiorgan failure multiple organ organ systems organs outcome overlapping pandemic Pathogenesis pathogenesis of COVID-19 Pathogens Result SARS-CoV-2 Sepsis serum cytokine Severe case severe COVID-19 severe COVID-19 disease Severe COVID-19 Infection severe COVID-19 patients similarity syndrome systemic inflammation tissue Treatment unique Urine Vascular viral disease viral particle virus while
[DOI] 10.3906/sag-2108-239 PMC 바로가기 [Article Type] Article

Inflammasomes and SARS-CoV-2 Infection

Review

Published on 2021-12-142022-10-28
Journal: Viruses
[Category] COVID-19, SARS,

[키워드] “cytokine storm” activate Activation Adaptive immune response affected caused coronavirus COVID-19 COVID-19 patient Cytokines develop disease form function gasdermin D IL-18 IL-1β induce Inflammasome inflammasomes Inflammatory cell death influenza A virus innate immune response innate immune system Innate immunity Local majority mild respiratory symptoms mRNA vaccine multiple organ people with COVID-19 pro-inflammatory cytokine pro-inflammatory cytokines Protective Protein protein complex pyroptosis recent SARS-CoV-2 SARS-COV-2 infection secretion severe COVID-19 severe disease Structure systemic inflammation virus infection worldwide pandemic
[DOI] 10.3390/v13122513 PMC 바로가기 [Article Type] Review

An Update on the Relationship of SARS-CoV-2 and Male Reproduction

Endocrinology

Published on 2021-11-232022-10-31
Journal: Frontiers in Endocrinology
[Category] COVID-19, MERS, SARS,

Organ-specific genome diversity of replication-competent SARS-CoV-2

복제 가능 SARS-CoV-2의 장기 특이적 게놈 다양성

Article

Published on 2021-11-162022-09-10
Journal: Nature Communications
[Category] MERS, SARS, 변종,

[키워드] accumulation acute respiratory syndrome acute respiratory syndrome coronavirus Analysis Asymptomatic clinical microbiology coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cases COVID-19 treatment death died disease Evolution Evolution of SARS-CoV-2 extrapulmonary organ extrapulmonary organs fatal disease Genome heart highlighting hygiene identify Immunocompromised patient Immunocompromised patients Impact Infection information kidney lead liver lung Lungs measure multiple organ multiple organs Mutation N501Y nucleotide organ organ-specific organs Pathogenesis plasma proof provide replicate Replication replication-competent SARS-CoV-2 reported respiratory respiratory symptom respiratory symptoms Respiratory system resulting SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Single nucleotide variant spleen Stage Still systemic manifestation the patient Treatment variants variants of concern Vero E6 VERO E6 cells Viral Viral load viral loads viral pathogenesis Viremia Virological virus infectivity VOCs Y453F
[DOI] 10.1038/s41467-021-26884-7 PMC 바로가기 [Article Type] Article

An outbreak of SARS-CoV-2 with high mortality in mink ( Neovison vison) on multiple Utah farms

여러 유타 농장에서 밍크(Neovison vison)의 사망률이 높은 SARS-CoV-2 발생

Research Article

Published on 2021-11-122022-09-12
Journal: PLoS Pathogens
[Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Animal host animal hosts animals anorexia bat bats breadth caused Chain Reaction clinical disease collected coronavirus damage death demonstrated disease distribution early phase edema effort epithelial F486L FIVE Gross high mortality hosts Human humans In situ hybridization indicate information interstitial pneumonia Localization localized infection lower respiratory system lung Lymph node measure mink moderate molecular Mortality multiple organ multiple organs Mutation nasal turbinates necropsy Neovison Novel coronavirus occurred outbreak pathology perivasculitis polymerase chain polymerase chain reaction Polymorphisms potential transmission PPE Prevent provided pulmonary congestion Pulmonary edema RBD mutation reported reservoir reservoirs Respiratory disease respiratory tract reveal reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 viral RNA sequenced severe acute respiratory syndrome Coronavirus severe respiratory disease Spread strain susceptible symptomatic the disease The United States tissue tissues tracheobronchial Transmission unique United States upper respiratory tract Utah Vasculitis viral infection Viral RNA Viral transmission virus virus transmission while whole genome Whole genome sequencing Y453F
[DOI] 10.1371/journal.ppat.1009952 PMC 바로가기 [Article Type] Research Article

Diagnostic dilemma: COVID-19 related cardiomyopathy or peripartum cardiomyopathy?

Case report

Published on 2021-11-012022-10-05
Journal: Journal of Cardiology Cases
[Category] 진단,

[키워드] Acute inflammation assist bilateral pulmonary infiltrate Cardiomyopathy Case report caused congestive heart failure coronavirus disease Coronavirus disease 2019 COVD-19 COVID-19 COVID-19 infection decompensated heart failure Dexamethasone diagnostic dilated cardiomyopathy discharged Dyspnea Echocardiogram echocardiography Ejection fraction feature heart failure hemodynamic instability highlight Hospital admission Infection inflammatory disease LVEF management multiple organ myocarditis Necrosis pandemic patient with COVID-19 Peripartum cardiomyopathy progression reduction in Remdesivir reported Shortness of breath ventricular Viral pneumonia women worsening X-ray
[DOI] 10.1016/j.jccase.2021.05.012 [Article Type] Case report

Covid-19 and oral diseases: Crosstalk, synergy or association?

코로나19와 구강질환: 누화, 시너지, 연관성?

Review

Published on 2021-11-012022-09-11
Journal: Reviews in Medical Virology
[Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Affect alterations angiotensin angiotensin-converting enzyme 2 association Bacterial Blister can not caused clinically cohort study coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Crosstalk Cytokines destruction disease Diseases dysfunction elevated Endothelial cell endothelial cells Endotheliitis erythematous Evidence exacerbating exhibit Express facilitate Gingiva gingivitis growth Gustatory Health human body hyperinflammation Immune-mediated impair Infection Infectious disease Inflammation Interaction lesion lesions Loss of Smell loss of smell and taste manifestation mechanism Multiple multiple organ multiple organs necrotic negative and positive oral cavity oral diseases. oral health oral infection oral manifestation oral tissue Pathogenesis Pathogens pathway Patient plaque plaques proinflammatory mediator proinflammatory mediators promote inflammation recent receptor reported salivary salivary gland SARS-CoV-2 severe acute respiratory syndrome Coronavirus Signs and symptoms subject subjects Symptom synergy Taste tissue homeostasis tissue inflammation viral entry viral infection viral replication virus virus spread
[DOI] 10.1002/rmv.2226 PMC 바로가기 [Article Type] Review

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021

2021 년 2 월 코네티컷의 개에있는 심한 급성 호흡기 증후군 코로나 바이러스 2 (SARS-COV-2)

Brief Report

Published on 2021-10-232022-09-10
Journal: Viruses
[Category] MERS, SARS, 변종, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 conducted Connecticut coronavirus coronavirus 2 COVID-19 D614G diagnostic died dog dominant ENhance Epidemiology Genetic Genome sequencing HCoV Human identify In situ hybridization Laboratory Lineage multiple organ multiple organs Mutation negative Nsp12 P323L Phylogenetic analysis positive postmortem examination public health real time-PCR respiratory reverse transcription RNA RNAscope RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus submitted substitutions sudden death The United States United States Viral Viral RNA virus Winter zoonotic
[DOI] 10.3390/v13112141 PMC 바로가기 [Article Type] Brief Report

Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP)

Original Paper

Published on 2021-10-122022-10-29
Journal: Infection
[Category] COVID-19, MERS, SARS,

[키워드] accumulated acute infection addition Affect analyses assessment Berlin clinical examination clinical study complement Comprehensive conducted consequence Course COVID COVID-19 pandemic disease severity Evidence examined Germany Health Health Assessment Health status Hospitalized individual Infection infection with SARS-CoV-2 initial internal medicine Kiel Local local public health Long Long COVID measure Medicine multiple organ National network neurological On-site examination over participant physical plasma platform population-based population-based cohort Potential protocol Quality of life Region Result Saliva SARS-CoV-2 SARS-CoV-2 infected individual SARS-COV-2 infection serum severity university Urine
[DOI] 10.1007/s15010-021-01707-5 PMC 바로가기 [Article Type] Original Paper