Traditional Chinese medicine network pharmacology study on exploring the mechanism of Xuebijing Injection in the treatment of coronavirus disease 20192019년 코로나바이러스 질병 치료에서 Xuebijing 주사의 메커니즘 탐구에 대한 중국 전통 의학 네트워크 약리학 연구Article Published on 2020-12-012022-08-31 Journal: Chinese journal of natural medicines [Category] MERS, SARS, 유전자 메커니즘, 치료제, [키워드] ACE2 Affect Analysis angiotensin Angiotensin-converting enzyme Anti-inflammatory Antiviral apigenin Chinese community-acquired pneumonia components Compound coronavirus disease Coronavirus disease 2019 COVID-19 Cytoscape database docked drug enrichment analysis Gene ontology help IL6 immune response indicated ingredient injection KEGG Kyoto Luteolin MAPK1 mechanism molecular docking multiple pathway multiple pathways network network pharmacology Ontology other compound other compounds overlapping Pathway enrichment analysis Perspective Pneumonia potential mechanism PPI network predict Proteins provided quercetin rutin S protein SALVIANOLIC ACID screened Sepsis Spike protein target target gene Target genes targets TCM TNF Traditional Chinese medicine treat Treatment with COVID-19 Xuebijing injection. [DOI] 10.1016/S1875-5364(20)60038-3 PMC 바로가기 [Article Type] Article
Systems Level Analyses Reveal Multiple Regulatory Activities of CodY Controlling Metabolism, Motility and Virulence in Listeria monocytogenes시스템 수준 분석을 통해 Listeria monocytogenes에서 대사, 운동성 및 독성을 제어하는 CodY의 여러 조절 활동이 밝혀졌습니다.Research Article Published on 2016-02-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] actA activate activator activity adaptation Affect Amino acid amino acids Analysis Bacteria bacterial pathogen Bacterial pathogens BCAA bind binding branch CodY condition conditions controlling dependent on DNA DNA binding environmental cues expression facilitate function functions Gene Expression Genes Genome gram Gram-positive bacteria growth Host identify identifying L . monocytogene Level Ligand ligands Listeria Listeria monocytogene Listeria monocytogenes mammalian metabolic genes metabolism modulate motility Multiple multiple pathway multiple pathways observation pathogen Pathogens pathway Pathways performed previous study prfA raised regulated regulator gene Regulatory regulatory network reported repress repressor respond response responses Sequencing Stress stress responses System Target genes thought traits Transcription transcription factor transcription factors virulence virulence gene virulence genes [DOI] 10.1371/journal.pgen.1005870 PMC 바로가기 [Article Type] Research Article