Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples말라리아에 감염된 여러 인간 혈액 샘플에서 하플로타입 빈도를 추정하기 위한 마르코프 체인 몬테 카를로 깁스 샘플러 접근법Methodology Published on 2021-07-102024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Gibbs sampler algorithm Haplotype reconstruction malaria markov chain monte carlo multiplicity of infection single nucleotide polymorphisms [DOI] 10.1186/s12936-021-03841-9 PMC 바로가기 [Article Type] Methodology
SARS-CoV-2 Production in a Scalable High Cell Density BioreactorArticle Published on 2021-06-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome addition animal component-free approved bioreactor carrier CelCradle Cell Cell culture cells conditions coronavirus COVID-19 Culture demonstrated density ENhance highest IMPROVE Inactivated vaccine Infection infectious dose log medium multiplicity of infection packed-bed pandemic per day Post-infection produced Production reported SARS-CoV-2 scalable bioreactor Seven severe acute respiratory syndrome coronavirus 2 TCID temperature tested tissue trypsin Vaccine vaccine production Vero Vero cells virus virus production virus spread viruses Volume while WHO whole virus vaccine [DOI] 10.3390/vaccines9070706 PMC 바로가기 [Article Type] Article
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico EvidencesPharmacology Published on 2021-06-172022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Against anionic anti-inflammatory activity antiviral activity Bacterial bovine lactoferrin cationic Cell cells components Concentration COVID-19 COVID-19 patients demonstrated disorder DNA down-regulate exocrine gland feature Genes glycoprotein Host host cells Hypothesis IL-6 in silico in vitro in vitro assays Infection inflammation sites inhibiting involved Ion iron homeostasis lactoferrin management multiplicity of infection neutrophil nucleus observation performed Proinflammatory cytokine RNA S glycoprotein SARS-CoV-2 SARS-COV-2 infection secreted spike supported Vero viral entry viral replication virus [DOI] 10.3389/fphar.2021.666600 PMC 바로가기 [Article Type] Pharmacology
Genetic diversity and genetic relatedness in Plasmodium falciparum parasite population in individuals with uncomplicated malaria based on microsatellite typing in Eastern and Western regions of Uganda, 2019–20202019-2020년 우간다 동부 및 서부 지역에서 단순 말라리아 환자의 Plasmodium falciparum 기생충 집단의 유전적 다양성과 유전적 관련성에 대한 마이크로새틀라이트 타이핑 기반 연구Research Published on 2021-05-312024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] genetic diversity malaria Microsatellite markers Multiclonal infections multiplicity of infection Parasite relatedness pfhrp2 deletion Rapid diagnostic tests [DOI] 10.1186/s12936-021-03763-6 PMC 바로가기 [Article Type] Research
Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2Article Published on 2021-04-092022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] A549 ACE2 Anti-SARS-CoV-2 Activity Antiviral antiviral activity approved blocked Caco-2 Calu-3 cell line Chloroquine Colon Concentration COVID-19 dependent on drug drug candidates Efficacy epithelial cell expressing Human Hydroxychloroquine indications Infection inhibited inhibitor less LINE lung cell lung cells medical need middle MOI multiplicity of infection pharmacological progeny Quinine Regulatory SARS-CoV-2 SARS-COV-2 infection Side effect tested therapeutic effect TMPRSS2 Treatment vaccination Vero cells while [DOI] 10.3390/v13040647 PMC 바로가기 [Article Type] Article
The Mechanism of PEDV-Carrying CD3 + T Cells Migrate into the Intestinal Mucosa of Neonatal PigletsArticle Published on 2021-03-122022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] addition blood circulation CD3 CD3+ T cells CD4 CD8 Contact demonstrated epidemic diarrhea implication increase in Infection integrin intestinal intestinal epithelial cell intestinal epithelium intestine intranasal inoculation Migration multiplicity of infection nasal Neonatal neonatal piglets occur Pathogenesis PEDV Prevent survived T cell T cells therapy transferred Viral transmission virus [DOI] 10.3390/v13030469 PMC 바로가기 [Article Type] Article
Development of a new barcode-based, multiplex-PCR, next-generation-sequencing assay and data processing and analytical pipeline for multiplicity of infection detection of Plasmodium falciparum플라스모디움 팔시파룸의 감염 다중성 탐지를 위한 새로운 바코드 기반 다중 PCR, 차세대 시퀀싱 분석법 및 데이터 처리 및 분석 파이프라인 개발Research Published on 2021-02-162024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Haplotype and strain MOI estimation multiplicity of infection Plasmodium falciparum STIM StrainRecon Transmission [DOI] 10.1186/s12936-021-03624-2 PMC 바로가기 [Article Type] Research
Parasite genetic diversity reflects continued residual malaria transmission in Vhembe District, a hotspot in the Limpopo Province of South Africa기생충 유전적 다양성은 남아프리카 림포포 주의 핫스팟인 베헴베 지구에서 지속적인 잔여 말라리아 전파를 반영합니다.Research Published on 2021-02-162024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] genetic diversity Limpopo Microsatellites multiplicity of infection Plasmodium falciparum Residual transmission South Africa Vhembe District [DOI] 10.1186/s12936-021-03635-z PMC 바로가기 [Article Type] Research
Genetic polymorphisms of Plasmodium falciparum isolates from Melka-Werer, North East Ethiopia based on the merozoite surface protein-2 ( msp-2 ) gene as a molecular marker멜카-웨레르, 에티오피아 북동부의 플라스모디움 팔시파룸 분리주에서 메로조이트 표면 단백질-2 (msp-2) 유전을 분자 마커로 기반으로 한 유전적 다형성Research Published on 2021-02-122024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Ethiopia genotyping merozoite surface protein 2 multiplicity of infection polymorphism [DOI] 10.1186/s12936-021-03625-1 PMC 바로가기 [Article Type] Research
Analysis of chicken macrophage functions and gene expressions following infectious bronchitis virus M41 infectionResearch Article Published on 2021-01-282022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] analyzed Apoptosis autophagy biological process bronchitis CCL4 CD36 Cell change CXCL12 expression expressions function Gene Expression Host host immune responses IBV IBV infection IBV-infected cells IFN-α IFN-γ IL-10 IL-1β IL-6 immune response Immunity Infection Infectious Bronchitis Virus Inflammation Interaction involved M41 Macrophage macrophage cell line Marco MDA5 MHCII MIF MOI morbidity and mortality multiplicity of infection pathogen pathogenic coronavirus Peripheral blood phagocytic Protein receptor Result significantly higher TLR3 TLR7 TNF-α viability virus virus replication were infected XCL1 [DOI] 10.1186/s13567-021-00896-z PMC 바로가기 [Article Type] Research Article