TLR8 agonist partially improves IFN-γ deficiency of NK cells in chronic hepatitis B through the synergy of monocytesArticle Published on 2023-02-012023-06-13 Journal: Alimentary pharmacology & therapeutics [Category] B형 간염, [키워드] Chronic Hepatitis B IFN-γ IL-10 Natural killer cells TLR8 [DOI] 10.1111/apt.17382
SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2DArticle Published on 2022-12-272023-07-11 Journal: Cell Reports [Category] COVID19(2023년), [키워드] antiviral immunity COVID-19 CP: Immunology CP: Microbiology Immune escape Innate immunity Natural killer cells NK cells NKG2D nsp1 SARS-CoV-2 [DOI] 10.1016/j.celrep.2022.111892 PMC 바로가기
Dendritic cell-natural killer cell cross-talk modulates T cell activation in response to influenza A viral infectionArticle Published on 2022-12-222023-06-14 Journal: Frontiers in Immunology [Category] Fulltext, 신종인플루엔자, [키워드] cross-talk dendritic cells H1N1 H3N2 Influenza Natural killer cells pandemic T cells [DOI] 10.3389/fimmu.2022.1006998 PMC 바로가기
Dynamic Evaluation of Natural Killer Cells Subpopulations in COVID-19 PatientsArticle Published on 2022-10-062022-11-15 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Admission analyzed Blood blood sample CD16 CD56 Cell change circulation collected COVID-19 COVID-19 patients cytokine cytolytic disease dynamic early stage EDTA evaluate expression flow cytometry forms IFN lymphocyte natural Natural killer cells NK cell no difference Non-survivors outcome outcomes patients PD-1 phenotype Prognostic value proportion SARS-CoV-2 SARS-COV-2 infection significantly study period subpopulation subtype Subtypes surface marker survival group survivor Total White blood cell [DOI] 10.3390/ijms231911875 PMC 바로가기
Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll-like receptors dictates pathophysiology of COVID-19 disease주로 전염증성 사이토카인, 사이토카인 수용체 및 톨 유사 수용체의 개별 유전적 다양성이 COVID-19 질병의 병태생리를 좌우합니다Review Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Alter B cells chemokine chemokines Clinical outcome clinical outcomes coding gene coding genes condition coronavirus coronavirus disease Coronavirus disease-19 Coronavirus-2 COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 severity cytokine Cytokine storm Cytokines determine exacerbate Gene Expression genes encoding Genetic genetic variability Genetic variation Genetic variations Host IL10 IL17 IL4 IL6 IL7 immune immune response immune responses Immunity individual Infection Inflammation Innate interferons Monocytes Mutation natural killer cell Natural killer cells Neutrophils nucleotide pathophysiology Patient polymorphism proinflammatory cytokines receptors respiratory symptoms response SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe respiratory symptoms severity of COVID-19 Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs susceptibility T cells the patient TLR TLR3 TLR7 TLR9 TLRs TNF Toll-like receptor Toll-like receptors understanding variants of concern Variation viral infection viral infections VOCs [DOI] 10.1002/jmv.27849 PMC 바로가기 [Article Type] Review
Natural killer cell exhaustion in SARS-CoV-2 infectionReview Published on 2022-08-012023-07-09 Journal: Innate immunity [Category] COVID19(2023년), [키워드] cell exhaustion. COVID-19 Natural killer cells SARS-CoV-2 Toll-like receptor [DOI] 10.1177/17534259221077750 PMC 바로가기 [Article Type] Review
NK cell dysfunction is linked with disease severity in SARS-CoV-2 patientsReview Published on 2022-08-012023-07-10 Journal: Cell biochemistry and function [Category] COVID19(2023년), [키워드] Immunotherapy Natural killer cells SARS-CoV-2 [DOI] 10.1002/cbf.3725 PMC 바로가기 [Article Type] Review
Cellular therapies for the treatment and prevention of SARS-CoV-2 infectionSARS-CoV-2 감염의 치료 및 예방을 위한 세포 요법Article Published on 2022-07-212022-09-11 Journal: Blood [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Antiviral Blood blood disorders cells cellular immunity Cellular therapies cellular therapy coronavirus described disorder Efficacy feasibility immune immune modulation include increased risk Infection Mesenchymal stromal cells modulating natural killer cell Natural killer cells PROTECT Regulatory T cell regulatory T cells Respiratory disease SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe respiratory disease stromal cells suppressed T cells therapy Treatment Trial viral shedding virus-specific T cell vulnerable patient [DOI] 10.1182/blood.2021012249 PMC 바로가기 [Article Type] Article
Plasticity of natural killer cells in pregnant patients infected with SARS-CoV-2 and their neonates during childbirthArticle Published on 2022-07-152023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] COVID-19 Natural killer cells Neonates Pregnancy SARS-CoV-2 [DOI] 10.3389/fimmu.2022.893450 PMC 바로가기
The KIR2DL2/HLA-C1C1 Gene Pairing Is Associated With an Increased Risk of SARS-CoV-2 InfectionKIR2DL2/HLA-C1C1 유전자 쌍은 SARS-CoV-2 감염 위험 증가와 관련이 있습니다Article Published on 2022-07-072022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] absence antiviral response association blood sample Blood samples causative agent Cell characterized controls COVID-19 COVID-19 infection COVID-19 pathogenesis COVID-19 patient COVID-19 patients dependent on detect DNA early phase frequencies Frequency function healthy controls healthy individuals HLA HLA-C Host in healthy individual incidence of COVID-19 Increased individual Infection Interaction Killer cell KIR KIR2DL2 KIR2DL3 KIR2DS3 Ligand Mild natural killer cell Natural killer cells NK cells no correlation Occurrence Pairing PCR primer protective effect receptor Region risk factor SARS-CoV-2 SARS-COV-2 infection severe disease Signaling significantly higher statistical analysis the healthy virus [DOI] 10.3389/fimmu.2022.919110 PMC 바로가기 [Article Type] Article