A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors출생 후 멜라닌 세포 계통의 유지와 멜라닌 세포 줄기 세포 전구체의 분화에서 SOX10의 이중 역할Research Article Published on 2013-07-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adult stem cells appear Author cause Cell cell fate cell type Critical differentiation downregulated downstream driving embryogenesis exacerbate examined Express expression Factor growth hair hair follicle haploinsufficiency idea in vivo increased expression leads Lineage maintain maintenance mechanism Melanocyte melanocytes melanogenesis MITF mitigate Mouse models negative regulation observation overexpression pigment portion precursor Premature prevented progenitor raise regulated Regulation Regulatory role Sox10 STEM stem cell stem cells survival sustained target Transcription transcription factor transcription factors [DOI] 10.1371/journal.pgen.1003644 PMC 바로가기 [Article Type] Research Article