An open-label multiyear study of sargramostim-treated Parkinson’s disease patients examining drug safety, tolerability, and immune biomarkers from limited case numbersarticle Published on 2023-05-222024-09-05 Journal: Translational Neurodegeneration [Category] update2024, [키워드] Granulocyte–macrophage colony-stimulating factor neuroprotection Parkinson’s disease regulatory T cells Sargramostim therapy Unified Parkinson’s Disease Rating Scale [DOI] 10.1186/s40035-023-00361-1 PMC 바로가기 [Article Type] article
Cerebrolysin Attenuates Exacerbation of Neuropathic Pain, Blood-spinal Cord Barrier Breakdown and Cord Pathology Following Chronic Intoxication of Engineered Ag, Cu or Al (50–60 nm) Nanoparticlesarticle Published on 2023-01-312024-09-02 Journal: Neurochemical research [Category] 대상포진, [키워드] Blood-spinal cord barrier cerebrolysin Engineered Nanoparticles Neuronal injury neuropathic pain neuroprotection [DOI] 10.1007/s11064-023-03861-8 PMC 바로가기 [Article Type] article
Natural and Semi-Synthetic Flavonoid Anti-SARS-CoV-2 Agents for the Treatment of Long COVID-19 Disease and Neurodegenerative Disorders of Cognitive DeclineReview Published on 2022-10-092023-07-11 Journal: Frontiers in bioscience (Elite edition) [Category] COVID19(2023년), [키워드] Alzheimer's disease Anti-inflammatory Anti-oxidant anti-viral phytochemicals ARDS chalcones cognition and memory flavones long COVID disease Neuroinflammation neuroprotection Nrf2 Parkinson's Disease SARS-CoV-2 [DOI] 10.31083/j.fbe1404027 [Article Type] Review
The pharmacokinetic property and pharmacological activity of acteoside: A reviewReview Published on 2022-09-012023-07-09 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), [키워드] Acteoside Anti-inflammation Anti-oxidation neuroprotection [DOI] 10.1016/j.biopha.2022.113296 PMC 바로가기 [Article Type] Review
Zinc as a Neuroprotective Nutrient for COVID-19–Related Neuropsychiatric Manifestations: A Literature ReviewArticle Published on 2022-01-112023-06-16 Journal: Advances in Nutrition [Category] COVID19(2023년), MERS, SARS, [키워드] COVID-19 Inflammation Micronutrient neuroprotection neuropsychiatry SARS-CoV-2 Supplementation Zinc [DOI] 10.1093/advances/nmab110 PMC 바로가기
Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical ViewpointCovid-19 Pandemic 동안 다발성 경화증 치료에 사용되는 약물 : 중요한 관점Article Published on 2022-01-012022-08-31 Journal: Current neuropharmacology [Category] SARS, 치료제, [키워드] Acetate activating acute respiratory distress acute respiratory distress syndrome Alemtuzumab analogue antiviral activity approved ARDS autoimmune disorder Autoimmune disorders caution cellular Cladribine concern COVID-19 COVID-19 infection COVID-19 pandemic cytokine Cytokine storm Defense depleting detrimental dimethyl fumarate disease Disease-modifying therapy drug early stage endothelial example fingolimod fumarate Glatiramer Glatiramer acetate health problem hyperinflammation Hyperinflammatory IFN IFNs immunomodulation interfere interferon Invasion lung Macrophage mechanisms Multiple multiple sclerosis Natalizumab neuroprotection Nrf-2 nucleotide nucleotides Ocrelizumab other organs overcome oxidative stress pathway potential risk Protective public health raised reinforcement respiratory distress risk risk-benefit ratio. Safe SARS-CoV-2 SARS-COV-2 infection sclerosis suggested syndrome Teriflunomide Treatment Viral viral replication [DOI] 10.2174/1570159X19666210330094017 PMC 바로가기 [Article Type] Article
Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analoguesReview Published on 2021-09-262022-10-30 Journal: Molecular Medicine [Category] COVID-19, SARS, [키워드] Abstract accumulating addressed affected analogue analogues candidate caused clinical evidence clinical trial consequence COVID-19 COVID-19 patient Critical care Darbepoetin deficiency detrimental dimension double-blind downstream Effect EPO expected gene product host responses hypoxia IMPROVE increasingly Inflammation Intensive kidney literature review lung male Manifestations microRNA Mortality multiple organ failure neuroprotection Neuropsychiatric outbreak outcome overcome pandemic Patient physiological placebo-controlled predicted Prognosis randomized clinical trial receive recent Recombinant human EPO Research SARS-CoV-2 serum severe COVID-19 Signaling Spread subject Substitution suggested Support treated Treatment [DOI] 10.1186/s10020-021-00381-5 PMC 바로가기 [Article Type] Review
Monocyte Locomotion Inhibitory Factor confers neuroprotection and prevents the development of murine cerebral malariaarticle Published on 2021-08-312024-09-01 Journal: International Immunopharmacology [Category] 말라리아, [키워드] Anti-inflammatory blood-brain barrier malaria MLIF Neuroinflammation neuroprotection [Article Type] article
Unravelling the Phytochemical Composition and the Pharmacological Properties of an Optimized Extract from the Fruit from Prunus mahaleb L.: From Traditional Liqueur Market to the Pharmacy ShelfArticle Published on 2021-07-222022-10-30 Journal: Molecules [Category] Coronavirus, SARS, [키워드] Prunus mahaleb L. ACE2 anti-bacterial effects anti-COVID-19 effects antimicrobial Bacterial blunting cells chicoric acid clinical symptom Colon downregulation Effect Effects Extract fruit Gene Expression gram H1299 human host in vitro indicate inhibit SARS-CoV-2 investigated Liqueur Local lung adenocarcinoma neuroprotection Pharmacy phenolic profile phytochemical property Protective effects Prunus mahaleb reducing scavenging shelf Strains Support tested TMPRSS2 TNFα Traditional Treatment ulcerative colitis VEGFA virus entry was measured [DOI] 10.3390/molecules26154422 PMC 바로가기 [Article Type] Article
Neurocritical Care Updates in Cerebrovascular Disease뇌혈관 질환의 신경 중환자 치료 업데이트Review Published on 2021-07-012022-09-11 Journal: Stroke [Category] 임상, [키워드] Abstract Blood blood pressure cerebral hemorrhage cerebrovascular cerebrovascular disorders Critical Critical care intensive care intensive care units Ischemic Stroke neuroprotection [DOI] 10.1161/STROKEAHA.121.033291 PMC 바로가기 [Article Type] Review