Antibiotic Management of Patients with Hematologic Malignancies: From Prophylaxis to Unusual InfectionsReview Published on 2022-07-012023-07-08 Journal: Current oncology reports [Category] COVID19(2023년), [키워드] febrile neutropenia Hematologic diseases hematologic malignancies Immunocompromised infection diseases infections neutropenia Prophylaxis [DOI] 10.1007/s11912-022-01226-y PMC 바로가기 [Article Type] Review
Efficacy and harms of tocilizumab for the treatment of COVID-19 patients: A systematic review and meta-analysis코로나19 환자 치료를 위한 토실리주맙의 효능과 유해성: 체계적 고찰 및 메타분석Meta-Analysis Published on 2022-06-032022-09-11 Journal: PLoS ONE [Category] 임상, 진단, [키워드] 95%CI adverse event adverse events AEs all-cause mortality analyses antibody Arm ARMS benefit bleeding Clinical improvement Clinical outcome Cohort cohorts Controlled trial COVID-19 COVID-19 adult patient COVID-19 adult patients database disease severity Effect evaluated Evidence Hospitalized hospitalized COVID-19 patients IL-6 impacted inverse main analyses mechanical ventilation Meta-analysis methodology moderate neutropenia nine no significant difference Other outcome performed Placebo Primary outcomes Probability Quality Random-effects meta-analysis Randomized controlled trials RCT RCTs receptors reduced risk risk of bia RoB searched severe AEs significant difference significantly Standard of care Subgroup analyses subgroup analysis systematic review TCZ thrombotic thrombotic event Thrombotic events Tocilizumab Treatment Weighting worsening [DOI] 10.1371/journal.pone.0269368 PMC 바로가기 [Article Type] Meta-Analysis
Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International StudyClinical Research Published on 2022-06-012024-09-04 Journal: Journal of the American Society of Nephrology [Category] 대상포진, [키워드] biologics children Hypogammaglobulinemia nephrotic syndrome neutropenia rituximab [DOI] 10.1681/ASN.2021111472 PMC 바로가기 [Article Type] Clinical Research
Up-regulated serum levels of interleukin (IL)-17A and IL-22 in Egyptian pediatric patients with COVID-19 and MIS-C: Relation to the disease outcomeCOVID-19 및 MIS-C가 있는 이집트 소아 환자의 인터루킨(IL)-17A 및 IL-22의 상향 조절된 혈청 수준: 질병 결과와의 관계Article Published on 2022-06-012022-09-11 Journal: Cytokine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] age ALT antimicrobial peptide antimicrobial peptides ARDS cellular children contribute COVID-19 CRP D-dimer died dimer elevated ELISA epithelial cell epithelial cells ferritin healthy control IL-17A IL-22 Increased infections Inflammatory Inflammatory marker inflammatory markers Interleukins LDH Level lymphopenia MIS-C MIS–C neutropenia neutrophilia not correlated outcome pathology Pathways Patient patients patients with COVID-19 patients with SARS-CoV-2 Pediatric patient peptides Protective relation Sample size SARS-CoV-2 serum serum ferritin level Serum level serum levels signaling pathways significantly higher stimulate syndrome synergistic synergistic action the disease thrombocytopenia up-regulated were measured with COVID-19 [DOI] 10.1016/j.cyto.2022.155870 PMC 바로가기 [Article Type] Article
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran ProgramCOVID-19 중증도와 관련된 유전자에 대한 페놈 전체 협회 연구에 따르면 Million Veteran Program에서 복잡한 질병과 공유된 유전학이 밝혀졌습니다.Article Published on 2022-04-282022-09-11 Journal: PLoS Genetics [Category] 변종, [키워드] ABO Affair African Analysis ancestry association Autoimmune autoimmune conditions Autoimmunity caution classification clinically complex disease condition conducted COVID-19 COVID-19 severity CRHR1 Critical Critical illness defined demonstrated determine EHR Electronic health record European fibrosis genetic architecture Genetic variant genetic variants genetics genome-wide association Genotype genotype-phenotype associations group Health health record heterogenous highlight Hispanic Hospitalization ICD immune host response increased risk inflammatory condition initiative LMNA locus Lupus mapped medical condition Million Veteran Program MUC5B MVP neutropenia Odds ratio outcome outcomes phenotype Phenotypes psoriasis pulmonary fibrosis reduced risk required reveal risk risk factor severe COVID-19 severity shared pathway stratified targets tested thrombosis Treatment TYK2 variant variants venous veteran veterans was performed with COVID-19 [DOI] 10.1371/journal.pgen.1010113 PMC 바로가기 [Article Type] Article
Clinical and Laboratory Findings of SARS-CoV-2 Infection in Children Younger than 6 Months Old: Neutropenia is More Common Not LymphopeniaArticle Published on 2022-04-052023-07-09 Journal: Journal of tropical pediatrics [Category] COVID19(2023년), [키워드] children COVID-19 neutropenia SARS-CoV-2 [DOI] 10.1093/tropej/fmac041 PMC 바로가기
Delayed Neutropenia in Heart Transplant Recipients Following COVID-19 DiagnosisConference abstract Published on 2022-04-012022-10-05 Journal: The Journal of heart and lung transplantation : th [Category] 유전자 메커니즘, [키워드] absolute neutrophil count acute illness administration ANC Asymptomatic Bone marrow Care cause colony stimulating factor complete blood count cough Course COVID-19 Delayed described diagnosed Diagnosis diarrhea dose Effect Fever G-CSF granulocyte heart Immunosuppression liver male medication medications MMF neutropenia neutrophil nine Patient Prednisone recipient recipients regimen report required resolved SARS-CoV-2 SARS-COV-2 infection second dose subsequent Support Symptom Testing Transplant viral infection viral infections [DOI] 10.1016/j.healun.2022.01.1024 [Article Type] Conference abstract
Distinctive pattern of neutrophil count change in clozapine-associated, life-threatening agranulocytosis Research Published on 2022-03-142022-10-05 Journal: The Pan African Medical Journal [Category] 유전자 메커니즘, [키워드] association benefit criteria electronic patient record exhibited identify life-threatening Local LTA monitoring neutropenia neutrophil neutrophil count neutrophil counts nine patients proportion recorded risk searched Treatment [DOI] 10.1038/s41537-022-00232-0 [Article Type] Research
A clinico-pathological study of COVID-19 associated rhino-orbital-cerebral mucormycosisObservational Study Published on 2022-03-012022-10-05 Journal: Indian journal of ophthalmology [Category] SARS, 임상, [키워드] age Analysis Angio-invasion blood sugar clinical collected correlated COVID-19 COVID-19-associated ROCM death diabetes Diabetes Mellitus diagnosis of COVID-19 Disease progression Factor feature group histopathological feature Histopathology Hyperinflammatory Inflammation majority male management Mucormycosis NET neutropenia Neutrophil extracellular trap Neutrophil-to-lymphocyte ratio NLR occurred onset of symptom outcome outcomes Pathogenesis Patient patients patients treated Poor Prognosis prognostic indicator retrospective second wave Stage stages of ROCM. uncontrolled vision [DOI] 10.4103/ijo.IJO_2366_21 PMC 바로가기 [Article Type] Observational Study
The Effect of Neutropenia and Filgrastim (G-CSF) on Cancer Patients With Coronavirus Disease 2019 (COVID-19) InfectionObservational Study Published on 2022-03-012022-10-05 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, [키워드] 24 hour 95% confidence interval absolute neutrophil count administration affected age ANC benefit Cancer cancer diagnosis cancer patient Cancer patients clinical impact Cohort coronavirus disease COVID-19 COVID-19 infection Cox model cytokine death determine Effect exhibited Factor filgrastim G-CSF granulocyte granulocyte colony stimulating factor growth factor hazard ratio Hospitalization Infection initiate Inpatients neutropenia oncology patient outcomes oxygen supplementation Patient potential risk predictor proliferation recombinant reducing Respiratory failure susceptibility treated with COVID-19 worsening [DOI] 10.1093/cid/ciab534 PMC 바로가기 [Article Type] Observational Study