Nicotine – Page 2 – Communicable Diseases Research

Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial

Randomized Controlled Trial

Published on 2022-07-012022-10-04
Journal: Intensive care medicine [Category] COVID19(2023년), SARS, 임상,

Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping

COVID-19의 신경 전달 및 흡연 및 전자담배에 의한 신경염증 상태에서 성상교세포 안지오텐신 전환 효소 2의 잠재적 역할

Article

Published on 2022-06-072022-09-11
Journal: Fluids and Barriers of the CNS [Category] COVID19(2023년), SARS, 치료기술,

[키워드] ACE2 ACE2 expression affecting Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 Astrocyte astrocytes Brain Cell cell type cells characterized Choroid plexus conducted COVID-19 COVID-19 patients COVID-19 severity cultured cells cytokine distribution domain endothelial cells entry receptor enzyme epithelial cell epithelial cells evaluate the effect exacerbate exacerbated expressed expression glial cell help highlight hypothalamus IL-5 IL-6 Immunocompromised immunohistochemistry immunomodulatory Inflammation manifestation marker Medulla oblongata meninges neural transmission Neurogenesis Neuron neurons Nicotine oblongata Pathogenesis pathogenesis of COVID-19 pericytes Post-infection Potential proinflammatory Real-time PCR responsible risk factor SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection shown significantly Smokers smoking stroma systemically third ventricle Transmission understanding ventricular were used western blot zone
[DOI] 10.1186/s12987-022-00339-7 PMC 바로가기 [Article Type] Article

Disorders of the Cholinergic System in COVID-19 Era—A Review of the Latest Research

Review

Published on 2022-01-082022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

[키워드] ACE Acetylcholine acetylcholinesterase agonist angiotensin-converting enzyme 2 antiviral drug antiviral drugs binding can be used cause caused change cholinergic cholinergic system complex conducted connection COVID-19 COVID-19 virus cytokine production Cytokine storm demonstrated develop disorder disrupt dysregulation Effect epitope example in vitro in vivo inhibit initiated Morphological negative influence nervous system Nicotine nicotinic receptors Non-invasive physiological Prevent receptor reduce Research review SARS-CoV-2 SARS-CoV-2 spike protein sequence Structure System the SARS-CoV-2 virus therapy these compound virus
[DOI] 10.3390/ijms23020672 PMC 바로가기 [Article Type] Review

Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression

SARS-CoV-2 감염과 관련된 분자 과정의 위험 중심적 차이: DNA 메틸화 및 유전자 발현의 결과

Research

Published on 2021-12-112022-09-11
Journal: Epigenetics & Chromatin [Category] SARS, 유전자 메커니즘,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Air pollutants airway epithelia Analysis ARRB2 association Asthma autosomal Bronchoalveolar lavage CA5B candidate gene changes in chronic conditions chronic obstructive COMT conducted COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 susceptibility CpG data set Diagnosis diesel exhaust DNA methylation downloaded epithelia exaggerated immune response exhibited explain Exploratory analysis exposure to Factor female Gene Expression gene expression patterns Genes GEO GPX1 Health highlight HS6ST2 immune genes imperative implicated inactivation increased risk individual Infection infections investigated involved loci lung magnitude male molecular molecular association molecular associations molecular basis molecular pattern molecular patterns mRNA expression nasal Nicotine nicotine dependence nitrogen nitrogen dioxide NLRP2 outcomes portal PRIM2 profile Repository respiratory Respiratory conditions Respiratory disease respiratory tissue Result risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection second severe acute respiratory syndrome Coronavirus Sex Sex difference Smokers smoking suggested supplementary material susceptibility TATDN1 the disease TLE1 understanding Variation while Whole blood X-linked X-linked gene
[DOI] 10.1186/s13072-021-00428-1 PMC 바로가기 [Article Type] Research

Association of Substance Use With Behavioral Adherence to Centers for Disease Control and Prevention Guidelines for COVID-19 Mitigation: Cross-sectional Web-Based Survey

Original Paper

Published on 2021-11-092022-10-31
Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, SARS,

[키워드] 95% CI accounted Addiction adherence Administered adverse outcomes age alcohol alcohol drinking Alcohol use Amazon’s Mechanical Turk Analysis black CDC center Connecticut Control covariate COVID-19 COVID-19 infection COVID-19 mitigation COVID-19 testing cross-sectional Daily determine drug elevated eligible evaluate finding Gender greater guideline Hispanic Hypothesis identity individual individuals likelihood Massachusetts men mental health New New York Nicotine Novel coronavirus objective Older Opioid use outcome pandemic platform positive COVID-19 prevention Primary outcome recruited reduce reported Result Rhode Island risk risk factor Risk factors SARS-CoV-2 secondary smoking Sociodemographic Sociodemographic characteristics spread of COVID-19 statistically stimulant use substance substance abuse Substance use Support survey tested vaccination variables was related white women
[DOI] 10.2196/29319 PMC 바로가기 [Article Type] Original Paper

Association of Health Status and Nicotine Consumption with SARS-CoV-2 positivity rates

Research

Published on 2021-10-032022-10-28
Journal: BMC Public Health [Category] COVID-19, MERS, SARS,

E-cigarette vape and lung ACE2 expression: Implications for coronavirus vulnerability

전자담배와 폐 ACE2 발현: 코로나바이러스 취약성에 대한 시사점

Article

Published on 2021-08-012022-09-11
Journal: Environmental toxicology and pharmacology [Category] 유전자 메커니즘,

[키워드] ACE2 ACE2 expression ACE2 mRNA Acetylcholine acetylcholine receptor Alter angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 appear Blood blood sampling both sexes changes cigarette coronavirus Coronavirus infection correlation COVID-19 COVID-19 infection downregulated E-cigarette expression female females Human individual Individual differences Infection investigated lung lung tissue male mechanism mice Nicotine Nicotine. not differ Protein receptor respiratory symptoms reveal severe respiratory symptom severe respiratory symptoms significant increase smoking subunit These data underlie viral entry with COVID-19
[DOI] 10.1016/j.etap.2021.103656 PMC 바로가기 [Article Type] Article

Circumvention of COVID-19-related restrictions on tobacco sales by the e-cigarette industry in South Africa and comparative analyses of heated tobacco product vs combustible cigarette volume sales during 2018-2020

Comparative Study

Published on 2021-07-012022-10-04
Journal: Preventive medicine [Category] SARS, 신약개발,

[키워드] activity African Analysis analyzed cannabidiol close monitoring company COVID-19 E-cigarettes examined Heated tobacco products highest lifting Nicotine promoted public health measure required South South Africa Tobacco vaping Volume
[DOI] 10.1016/j.ypmed.2021.106526 PMC 바로가기 [Article Type] Comparative Study

SARS-Co-V2 infection in never, former, and current tobacco/nicotine users: a cohort study of 4040 Egyptian healthcare workers

Research

Published on 2021-06-282022-10-28
Journal: BMC Public Health [Category] COVID-19, MERS, SARS,

[키워드] adjusted adverse outcomes Analysis analyzed association baseline Cairo Characteristics co-morbidities Cohort cohort study confounder country COVID-19 COVID-19 case COVID-19 severity demographics Egypt Evidence examined Follow-up Frequency HCW HCWs healthcare facility healthcare worker Healthcare workers Impact Infection multivariable logistic regression Nicotine performed positive Positive test Prevalence Previous studies proportion prospective cohort study Result risk SARS-Co-V2 SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 tests significantly smoker smoking Study design supplementary material Symptom Symptoms Tobacco took place
[DOI] 10.1186/s12889-021-11290-x PMC 바로가기 [Article Type] Research

Temporal proteomic changes induced by nicotine in human cells: A quantitative proteomics approach

인간 세포에서 니코틴에 의해 유발된 시간적 단백질체 변화: 정량적 단백질체학 접근법

Article

Published on 2021-06-152022-09-11
Journal: Journal of proteomics [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] A549 A549 cell line A549 cell lines affected alteration approach association biological processe Cancer cell line change changes in complement complement system complex compounds concerning COVID19 dataset decrease diabetes disease Diseases Effect event FAIMS heart disease host protein immune pathways implication in vitro in vivo Infection mitochondrial Nicotine Phosphorylation Protein protein-protein interactions proteome proteomes proteomic proteomics public health quantified Quantitative Real time search reported RTS SARS-CoV2 SH-SY5Y smoke smoking smoking cessation stroke susceptibility susceptibility to infection Temporal TMTpro. Tobacco Treatment type 2 diabetes Viral protein Viral proteins
[DOI] 10.1016/j.jprot.2021.104244 PMC 바로가기 [Article Type] Article