Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings Research Published on 2022-06-142022-10-05 Journal: Molecular Psychiatry [Category] 바이오마커, 임상, [키워드] activity affected Brain caused change changes in cognitive Cognitive impairment Complication consequence correlated correlation correlations COVID-19 COVID-19 cases debatable described dysfunction Evidence expected Follow-up fraction immune marker immune markers impairment implication individuals Inflammatory majority Mild moderate molecular MRI neurological Neuropsychiatric occur ocular persistence persistent Psychiatric recorded rehabilitation required Severe case Severe infection Symptom upregulation vascular lesion viral infections were assessed while [DOI] 10.1038/s41380-022-01632-5 [Article Type] Research
Effects of delay in anti-vascular endothelial growth factor intravitreal injections for neovascular age-related macular degeneration신생혈관 연령관련 황반변성에 대한 항혈관내피성장인자 유리체내 주사 지연 효과Article Published on 2022-06-012022-09-12 Journal: Graefe's Archive for Clinical and Experimental Oph [Category] MERS, 진단, [키워드] Age-related macular degeneration AMD Anatomic anti-vascular Anti-VEGF bleeding Care Clinical data COVID-19 defined Delay Disruption Effect endothelial eye eyes feature First wave growth factor hemorrhage injection interval intravitreal injection OCT. ocular Odds ratio outcomes Patient patients patients treated Standard deviation tomographic image visual acuity worsened worsening [DOI] 10.1007/s00417-021-05505-5 PMC 바로가기 [Article Type] Article
CRVO associated with COVID-19 and MTHFR mutation in a 15-year-old maleCase report Published on 2022-06-012022-10-05 Journal: American Journal of Ophthalmology Case Reports [Category] 변종, 진단, [키워드] anterior chamber Cell Central retinal vein occlusion children complications of COVID-19 COVID-19 diagnostic edema etiologies excluded expand Extensive Gene Genetic hemorrhages hospital hypercoagulable Importance Infection Inflammatory initial knowledge Laboratory macular star male MTHFR Mutation Nasopharyngeal swab neuroretinitis observation ocular Patient positive provide retinal vein Viral load vitreous with COVID-19 [DOI] 10.1016/j.ajoc.2022.101522 [Article Type] Case report
Hemi- and Central Retinal Vein Occlusion Associated with COVID-19 Infection in Young Patients without Known Risk FactorsResearch article Published on 2022-06-012022-10-05 Journal: Ophthalmology. Retina [Category] 바이오마커, 변종, [키워드] age Anti-VEGF association Case series case sery Clinical course Complete Confirmed COVID-19 infection coronavirus disease counting fingers COVID-19 COVID-19 diagnosis COVID-19 infection diabetes edema event exclusion criteria eye Factor Final Follow-up follow-up period Hemi Hospitalization Hospitalized hypercoagulable states hypertension Infection Injections Intubated intubation macular edema measure median median age median time multicenter obesity ocular ophthalmic Patient potential risk presenting raise raised ranged reported Result Retinal vascular disease retinal vein retinal vein occlusion retrospective Symptom thromboembolic complication treated Vascular Venous Thromboembolism visual acuity with COVID-19 [DOI] 10.1016/j.oret.2022.02.004 [Article Type] Research article
Dexamethasone: Insights into Pharmacological Aspects, Therapeutic Mechanisms, and Delivery SystemsReview Published on 2022-05-092022-10-04 Journal: ACS Biomaterials Science & Engineering [Category] 신약개발, [키워드] Administered allergies approach Autoimmune diseases Cancer Cell COVID-19 delivery Dexamethasone disease Diseases disorders drug drug delivery Drug repurposing Effect elicit healthy hyperglycemia hypertension inhibiting insight nanomaterials ocular organ phosphate polymers provide Research Side effects System tissue tissue engineering. treat variety [DOI] 10.1021/acsbiomaterials.2c00026 PMC 바로가기 [Article Type] Review
Increased proinflammatory cytokines in tears correspond with conjunctival SARS-CoV-2 positivity in symptomatic COVID-19 patients눈물의 증가된 전염증성 사이토카인은 증상이 있는 COVID-19 환자의 결막 SARS-CoV-2 양성과 일치합니다Article Published on 2022-05-042022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료법, [키워드] Biomarker Biomarkers collected Concentration conjunctival conjunctival sac Conjunctival secretion Conjunctival secretions COVID-19 patient COVID-19 patients cytokine level Cytokines determined by GM-CSF greater IFN-γ IL-10 IL-12 IL-1B IL-2 IL-4 IL-5 IL-6 IL-8 Increased Infection Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators innate immune system magnetic bead ocular ophthalmic pathology Patient PCR testing positive Proinflammatory cytokine RNA RT-PCR testing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity SARS-CoV-2 viral load selected significantly Swab Symptom symptomatic Tear tear film tears TNF-α Viral RNA [DOI] 10.1038/s41598-022-11285-7 PMC 바로가기 [Article Type] Article
Retinal Findings of Hospitalized Neonates Recovered from COVID-19 Infection: A Prospective, Observational, Descriptive StudyObservational Study Published on 2022-04-052022-10-04 Journal: Journal of tropical pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome age alteration caused change Complication coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection duration of hospitalization Effect evaluated female Hospitalization indirect ophthalmoscopy initial male multiple tissue Neonatal Neonate Neonates ocular organs Patient performed Prospective recovered reported Retina retinal damage Retinal Finding retinal findings. the mean [DOI] 10.1093/tropej/fmac036 PMC 바로가기 [Article Type] Observational Study
Tracing the SARS-CoV-2 infection on the ocular surface: Overview and preliminary corneoscleral transcriptome sequencing안구 표면의 SARS-CoV-2 감염 추적: 개요 및 예비 각막 공막 전사체 시퀀싱Article Published on 2022-04-012022-09-11 Journal: Experimental eye research [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] absence ADAMTS4 Analysis AQP5 associable caused Cluster Clusters component Cornea Corneal Corneoscleral ring COVID-19 CTRL Cytokines DEGs differentially expressed gene Differentially expressed genes Donor down-regulated gene down-regulated genes enrichment analysis Eye bank gene expression profile Gene ontology Genes genomic genomic RNA GO analysis GO term IL6 Illumina inactive indicated infected individual infected individuals Infection interferon interferon pathway ISG ISG15 ISGs Local Manifestations MMP1 modulation molecular mechanism molecular mechanisms ocular Ocular surface pathway PCA PCA analysis performed Perturbation positive Post-mortem principal Principal component principal component analysis proinflammatory cytokines Protective qRT-PCR RNA RNA-sequencing RSAD2 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2. several gene several genes Support tears the interferon the SARS-CoV-2 tissue tracing transcriptional Transcriptome transcriptome analysis transcriptome sequencing virus was performed [DOI] 10.1016/j.exer.2022.108975 PMC 바로가기 [Article Type] Article
Self-reported symptoms of mask-associated dry eye: A survey study of 3,605 peopleObservational Study Published on 2022-04-012022-10-05 Journal: Contact lens & anterior eye : the journal of the British Contact Lens [Category] COVID19(2023년), SARS, 임상, [키워드] age analysed association Clinical sign COVID-19 COVID-19 pandemic cross-sectional described Dry Dry eye exacerbated eye care face Face mask Factor female form General population Google identify increase in mitigate ocular Ocular discomfort. participant Patient positive Prevalence professional proportion reported SARS-CoV-2 self-reported symptom Sex social media platforms Spread spread of COVID-19 Symptom Symptoms widespread [DOI] 10.1016/j.clae.2021.01.003 PMC 바로가기 [Article Type] Observational Study
Reactivation of Herpes Simplex Keratitis on a Corneal Graft Following SARS-CoV-2 mRNA VaccinationSARS-CoV-2 mRNA 백신 접종 후 각막 이식편에서 단순 포진 각막염의 재활성화Case Reports Published on 2022-04-012022-09-11 Journal: Medical archives (Sarajevo, Bosnia and Herzegovina [Category] COVID19(2023년), SARS, 치료제, [키워드] acyclovir Antiviral Antiviral treatment artificial tears blepharitis cause caused causes colonization conjunctivitis Cornea Corneal corneal opacity COVID-19 COVID-19 vaccine COVID-19 vaccines epithelial Graft Herpe herpes herpes simplex herpes simplex keratitis herpes simplex virus herpes simplex virus type 1 herpes viruses herpetic keratitis HSV-1 include keratitis less loss of vision manifestation morbidity moxifloxacin mRNA mRNA vaccine occurred ocular Patient patients Penetrating Penetrating keratoplasty Prophylactic Reactivation receiving reported SARS-CoV-2 simplex the vaccine these viruses treated Treatment Uveitis vaccination vaccination. virus virus vision [DOI] 10.5455/medarh.2022.76.146-148 PMC 바로가기 [Article Type] Case Reports