other treatment – Page 2 – Communicable Diseases Research

Serologic response to COVID-19 infection and/or vaccine in cancer patients on active treatment

활성 치료 중인 암 환자의 COVID-19 감염 및/또는 백신에 대한 혈청학적 반응

Article

Published on 2021-12-012022-09-11
Journal: ESMO open [Category] SARS, 변종, 치료법,

Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial

중증 코로나19 폐렴으로 입원한 환자를 대상으로 한 토실리주맙과 렘데시비르: 무작위 임상시험

Randomized Controlled Trial

Published on 2021-11-012022-09-11
Journal: Intensive care medicine [Category] 임상, 진단, 치료제,

[키워드] 7-category ordinal scale 95% CI adverse event assigned benefit clinical status Combination Corticosteroid Corticosteroids COVID-19 COVID-19 pneumonia Cox proportional hazard defined demonstrated died double-blind enrolled evaluated greater hospital discharge hospitalized patient intravenously investigator median time Multicenter trial occurred Ordinal Scale other treatment other treatments oxygen Patient patients patients hospitalized Placebo placebo-controlled Pneumonia Primary outcome provide randomization Randomized randomized clinical trial Randomly receive Remdesivir Serious Adverse Events severe COVID-19 Severe COVID-19 pneumonia supplemental oxygen Tocilizumab Trial
[DOI] 10.1007/s00134-021-06507-x PMC 바로가기 [Article Type] Randomized Controlled Trial

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

영국 지역 사회에서 합병증의 위험이 높은 사람들의 Covid-19에 대한 흡입 부데소니드 (원칙) : 무작위, 제어, 오픈 라벨, 적응 형 플랫폼 시험

Randomized Controlled Trial

Published on 2021-09-042022-08-13
Journal: Lancet (London, England) [Category] MERS, SARS, 임상,

[키워드] absolute difference Adaptive platform trial Admission analysed assigned Bayesian credible interval Bayesian models BCI benefit Budesonide chance Community Comorbidities Complication complications COVID-19 COVID-19 in patient credible interval death Effectiveness Efficacy eligible Eligible participants Endpoint enrolment estimated rate finding funding greater hazard ratio high risk higher risk hospital Hospital admission Hospital admissions IMPROVE include individual inhaled budesonide inhaled budesonide reduce Innovation ISRCTN ISRCTN registry multi-arm multicentre Odds ratio Older Open-label other treatment other treatments outcome participant people with COVID-19 Platform trial primary analysis primary analysis population primary care Probability randomisation randomised Randomly receiving reducing Registered SARS-CoV-2-positive participant SARS-CoV-2-positive participants Serious Adverse Event Serious Adverse Events superiority criterion threshold Time to recovery Trial United Kingdom usual care usual care alone usual care group
[DOI] 10.1016/S0140-6736(21)01744-X PMC 바로가기 [Article Type] Randomized Controlled Trial

Arbidol is associated with increased in-hospital mortality among 109 patients with severe COVID-19: A multicenter, retrospective study

Research Theme 1: COVID-19 Pandemic

Published on 2021-07-172022-10-31
Journal: Journal of Global Health [Category] COVID-19,

[키워드] 95% confidence interval addition adjusted age Analysis analyzed antiviral agent antiviral therapy antiviral treatments Arbidol association co-morbidities Combination complications COVID-19 patients demographics determine died discharged Effect Effectiveness enrolled hospital Hospitalization IFN-α in-hospital mortality indicated interferon-alpha Intervention Laboratory Logistic regression monotherapy multicenter Odds ratio oseltamivir other treatment Patient Prognosis Result Retrospective study ribavirin severe COVID-19 patient severe COVID-19 patients survival Treatment variables Wuhan, China
[DOI] 10.7189/jogh.11.05017 PMC 바로가기 [Article Type] Research Theme 1: COVID-19 Pandemic

Use of Remdesivir in the treatment of Coronavirus Disease 2019 (COVID-19) infection among Sudanese patients: a case series

수단 환자의 코로나바이러스 질병 2019(COVID-19) 감염 치료에 렘데시비르 사용: 사례 시리즈

Case Reports

Published on 2021-06-292022-09-11
Journal: F1000Research [Category] SARS, 치료제,

[키워드] adverse event adverse events affecting association broad spectrum case sery conducted coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 infection determine died Frequency Hypoalbuminemia Hypotension ICU Imperial Hospital in vitro in vivo increased liver enzyme increased liver enzymes Infection intensive care intensive care unit liver liver enzymes male other treatment other treatments pandemic Patient Population Remdesivir Severe case severe cases Side effect Side effects steroid Steroids Sudan Sudanese patients. supportive therapy therapy treating COVID-19 Treatment treatment for COVID-19 Usage
[DOI] 10.12688/f1000research.51375.2 PMC 바로가기 [Article Type] Case Reports

Matched cohort study on the efficacy of tocilizumab in patients with COVID-19

Research article

Published on 2021-06-012022-10-05
Journal: One Health [Category] 유전자 메커니즘,

Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods

SARS-CoV-2 간접 및 직접 RT-qPCR 검출 방법 비교

Comparative Study

Published on 2021-05-172022-09-01
Journal: Virology Journal [Category] SARS, 진단, 치료기술,

[키워드] 2019-nCoV Analysis approach best BGI boiling caused Clinical diagnosis comparable Cost analysis COVID-19 COVID-19 pandemic Critical Ct values Detection limit detection system diagnostic diagnostics Direct detection evaluated exhibited extracted RNA gold gold standard handling initial Invitrogen isolation procedures less lysis buffer methodology MOST NEB other treatment Patient performed Primers provided purified viral RNA Qiagen reagents reduced Result RNA extraction RNA extraction kit RNA isolation RNase RNase inhibitor RT-qPCR SARS-CoV-2 SARS-CoV-2 virus sensitive sensitivity specificity supplementary material SYBR Green TaqMan tested the SARS-CoV-2 virus Universal Viral viral genome Viral RNA virus
[DOI] 10.1186/s12985-021-01574-4 PMC 바로가기 [Article Type] Comparative Study

Characteristics of systematic reviews evaluating treatments for COVID-19 registered in PROSPERO

PROSPERO에 등록된 코로나19 치료제를 평가하는 체계적인 리뷰의 특징

Original Paper

Published on 2021-04-232022-09-11
Journal: Epidemiology and Infection [Category] MERS, SARS, 치료제,

[키워드] (traditional Chinese medicine analysed Analysis anti-inflammatory treatment antiviral agent Antiviral agents antiviral therapy China Chinese Chloroquine chloroquine/hydroxychloroquine completion rate convalescent patient Convalescent patients cooperation coronavirus coronavirus disease coronavirus disease-2019 country COVID-19 COVID-19 treatment COVID-19 treatments deficiencies deficiency Descriptive analyses exhibited expression Favipiravir followed by generate highest Hospital stay Hydroxychloroquine Immunotherapy institution interferon International Intervention Medicine mortality rate other treatment other treatments outcome outcome measure outcome measures plasma plasma therapy problems PROSPERO Registered rehabilitation Remdesivir Research research collaboration respiratory Respiratory Support ribavirin Ritonavir searched secondary outcome Support systematic review systematic reviews TCM therapy Traditional Traditional Chinese medicine Treatment treatments for COVID-19 university was used
[DOI] 10.1017/S0950268821001321 PMC 바로가기 [Article Type] Original Paper

Efficacy and safety outcomes of proposed randomized controlled trials investigating hydroxychloroquine and chloroquine during the early stages of the COVID-19 pandemic

COVID-19 전염병의 초기 단계에서 하이드록시클로로퀸과 클로로퀸을 조사하는 제안된 무작위 대조 시험의 효능 및 안전성 결과

Review

Published on 2021-04-012022-09-11
Journal: British Journal of Clinical Pharmacology [Category] 임상, 치료제,

[키워드] accounted adverse events approach Chloroquine clinical Clinical improvement Clinical outcome Clinical practice clinical trials Combination COVID-19 COVID-19 pandemic database diagnosed with COVID-19 domain early stage early stages Efficacy evaluate Final Health Organization heterogeneous Hydroxychloroquine interquartile interquartile range median Mortality other treatment other treatments outcome outcome measure outcomes pandemic Patient patients with COVID-19 primary clinical outcome primary endpoints randomized clinical trial Randomized controlled trial RCT RCTs Registered registry Regulatory reported Research Sample size searched Serious Adverse Events translate Treatment Trial unique was performed World Health Organization
[DOI] 10.1111/bcp.14598 PMC 바로가기 [Article Type] Review

Influence of the COVID-19 Pandemic on Dental Emergency Admissions in an Urgent Dental Care Service in North Italy

Article

Published on 2021-02-122022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, MERS,