Risk of vertical transmission of SARS CoV-2 infection to neonates born to covid positive mothers: A pilot study from a tertiary care hospital of North India코로나 바이러스 양성 산모에게서 태어난 신생아에게 SARS CoV-2 감염의 수직 전파 위험: 북인도의 3차 병원에서 실시한 파일럿 연구Article Published on 2022-10-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] amniotic Amniotic fluid Analysis anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody anti-SARS-CoV-2 IgM antibody biological sample Blood Breast breast milk Care Cervicovaginal secretion clinical implication conducted Cord blood Cord blood IgG-IGM COVID-19 demonstrated disease disease severity fetal fetal membrane greater hospital IgG IgM antibodies Immunoglobulin India Infection material mechanism membrane mother Nasopharyngeal swab Neonatal Neonate Neonates North passive immunity performed pilot study positive positive correlation pregnant women Presence Prospective Study risk RT-PCR SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection secretion shown tested Transmission unlikely vertical transmission virus women [DOI] 10.1016/j.jiac.2022.06.004 PMC 바로가기 [Article Type] Article
Durable antibody and effector memory T cell responses in breastmilk from women with SARS-CoV-2Article Published on 2022-09-122022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] antibody asked B.1.1.7 B.1.351 Beta binding Blood breast milk breast permeability breastmilk CCR7 CD4 CD45RO CD8 T cell Cell complex COVID-19 COVID-19 vaccine D614G domain dried blood spot effector memory elect enrolled expressed first COVID-19 symptom flow cytometry Gamma IgA IgA response IgG IgM Immunity Immunoglobulin indicated Infant lactating memory memory T memory T cells milk mother mucosal mucosal immunity neutralize neutralized Neutralizing P.1 participant passive immunity permeability positive potassium ion pregnant women Protective reactivity receive robust SARS-CoV-2 SARS-COV-2 infection second set significantly higher sodium Stool T cell T cell response tested the spike protein timepoint was collected were assessed women [DOI] 10.3389/fimmu.2022.985226 PMC 바로가기
Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort studyArticle Published on 2022-09-012022-11-15 Journal: Journal of reproductive immunology [Category] SARS, 변종, 진단, [키워드] 1.26 anti-SARS-CoV-2 antibodies antibody Antibody titer antibody transfer booster vaccination Breast breast milk Breastfeeding cohort study Concentration conducted Confirmed COVID-19 infection COVID-19 evaluated group highlight humoral immune response immune Infection IQR lactation moderate mother neutralization capacity Newborn omicron pandemic Passive passive immunity positive correlation Pregnancy prenatal Prospective Study RBD SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination serum significantly higher single dose spike IgA the median transfer Vaccine variant women [DOI] 10.1016/j.jri.2022.103685 PMC 바로가기
Decreased Passive Immunity to Respiratory Viruses through Human Milk during the COVID-19 PandemicArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] 진단, [키워드] antibodies antibody association binding breast milk circulation consequence Coronaviruses COVID-19 COVID-19 pandemic decrease Decreased develop explain HCoV-HKU1 HCoV-NL63 HCoV-OC43 help Hospital admission Hospitalization Human human milk Humoral immunity hygiene IgA IgG IgG level immune system Immunity Infant Infants Infection infections Influenza lifted lockdown Luminex assay measure milk mother pandemic Passive passive immunity predict Prevent preventative measure preventative measures provide reduced respiratory respiratory infections respiratory syncytial virus respiratory virus resulting RSV seasonal coronavirus serum subsequent viral respiratory virus viruses was reduced [DOI] 10.1128/spectrum.00405-22 PMC 바로가기
Survival of Vaccine-Induced Human Milk SARS-CoV-2 IgG, IgA and SIgA Immunoglobulins across Simulated Human Infant Gastrointestinal Digestion인간 유아 위장 소화를 통한 백신 유도 모유 SARS-CoV-2 IgG, IgA 및 SIgA 면역글로불린의 생존Article Published on 2022-08-172022-09-12 Journal: Nutrients [Category] SARS, 진단, [키워드] adenovirus-based antibody Breastfeeding breastmilk COVID-19 COVID-19 pandemic Degradation digestion dose evaluated Evidence Gastrointestinal GI Tract help Human human milk IgA IgA antibody IgG Immunoglobulin immunoglobulins in vitro Inconclusive Infant information intestinal lactating milk mother mRNA-based vaccine natural infection passive immunity persistence Pfizer/BioNTech produced PROTECT protective role protocol recent reduced reduction SARS-CoV-2 SARS-CoV-2 IgG secretory IgA SIgA the SARS-CoV-2 virus the spike protein the vaccine transfer vaccination Vaccine women [DOI] 10.3390/nu14163368 PMC 바로가기 [Article Type] Article
Antibodies in the breastmilk of COVID-19 recovered women코로나19 회복된 여성의 모유에 있는 항체Article Published on 2022-08-112022-09-11 Journal: BMC Pregnancy and Childbirth [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome coronavirus anti-RBD IgA anti-SARS-CoV-2 IgG antibodies antibody antibody levels Asymptomatic benefit Breast breast milk Breastfeeding breastmilk characterized clinical symptom Clinical symptoms collected Concentration control group coronavirus coronavirus 2 COVID-19 COVID-19 disease enzyme enzyme-linked immunosorbent assay Human human milk IgA IgG IgG antibodies IgG antibody immunization immunoglobulins Immunoglobulins, passive immunity Infant Infants lactating mother no statistically significant difference passive immunity passive immunization positive protective factor RBD IgA respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test serum serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity statistically significant difference symptomatic and asymptomatic symptomatic infection test result virus transmission was performed with COVID-19 women [DOI] 10.1186/s12884-022-04945-z PMC 바로가기 [Article Type] Article
Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milkArticle Published on 2022-08-102022-11-15 Journal: Clinics [Category] 진단, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody Antibody Response approach B lymphocyte bacterial antigen Bioactive factors Breast breast milk Breastfeeding chemokines complement component cytokine elevated Factors fatty acids function Growth factors hormone Human IgA IgA antibodies IgA antibody IgG antibody IMPROVE inactivated induce lactation lactoferrin leukocyte mammary Maternal maternal immunization MicroRNAs nucleic acids oligosaccharides pandemic passive immunity performed Placenta Plasma cell plethora polysaccharide Pregnancy produced Proteins respiratory infections respiratory tracts secretion secretory secretory IgA Secretory IgA antibodies. Specific specific antibody unique vaccination Vaccine Vaccines virus virus-neutralizing viruses [DOI] 10.1016/j.clinsp.2022.100093 PMC 바로가기
Neutralizing SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Give Patients with X-Linked Agammaglobulinemia Limited Passive Immunity to the Omicron VariantArticle Published on 2022-08-012022-11-15 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] agammaglobulinemia antibody appear collected Concentration COVID-19 Donor Immunity Immunoglobulin immunoglobulin replacement therapy in vitro individual infections Karolinska University Hospital Limited neutralize neutralizing capacity observation omicron original virus strain pandemic Passive passive immunity Patient plasma plasma concentration Prevent Primary Immunodeficiency product Protective reflect remained Sample SARS-CoV-2 SARS-CoV-2 antibody symptomatic the SARS-CoV-2 therapy unit variant were assessed X-linked agammaglobulinemia X-linked agammaglobulinemia. XLA [DOI] 10.1007/s10875-022-01283-9 PMC 바로가기
Evidence of Maternal Antibodies Elicited by COVID-19 Vaccination in Amniotic Fluid: Report of Two Cases in Italy양수에서 COVID-19 백신 접종으로 유도된 모체 항체의 증거: 이탈리아의 2건의 사례 보고Case Reports Published on 2022-07-212022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] administration amniotic Amniotic fluid Antenatal anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibodies antibody Birth center collected COVID-19 COVID-19 vaccination Critical cross Efficiency elicited evidence of fetus gestation high risk highlighting IgG immunization Infant Infants Infectious disease Infectious diseases Italy Kinetics Maternal mechanism Newborn offer outcomes passive immunity persistence Placenta Pregnancy pregnant women prevention regimens report response to vaccination SARS-COV-2 infection second dose serum severe disease tested titer titers transfer vaccination women [DOI] 10.3390/v14071592 PMC 바로가기 [Article Type] Case Reports
Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled TrialRandomized Controlled Trial Published on 2022-07-012022-10-05 Journal: Chest [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 28-day mortality activity acute respiratory symptom adjusted odds ratio adults hospitalized analyzed anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody assigned blinded clinical clinical status clinical trial convalescent plasma convalescent plasma group COVID-19 death died discharged Efficacy groups highest hospital Illness severity improve clinical outcomes lowest multicenter multivariable Neutralizing not differ outcome outcomes passive immunity Patient Placebo placebo group placebo-controlled plasma primary analysis Primary outcome randomization randomized clinical trial randomized patients Randomly receive Registration Regression model Result SARS-CoV-2 SARS-COV-2 infection Secondary analyses selected seronegative seven-category ordinal scale stratified supported the placebo group Treatment treatments for COVID-19 Trial trial participant with COVID-19 [DOI] 10.1016/j.chest.2022.06.029 [Article Type] Randomized Controlled Trial