Interleukin-6 inhibitors reduce mortality in coronavirus disease-2019: An individual patient data meta-analysis from randomized controlled trialsInterleukin-6 억제제는 코로나바이러스 질병-2019의 사망률을 감소시킵니다: 무작위 대조 시험의 개별 환자 데이터 메타 분석Meta-Analysis Published on 2022-07-012022-09-11 Journal: European journal of internal medicine [Category] 임상, [키워드] 95%CI age Analysis confidence confidence interval coronavirus COVID-19 COVID-19 patients data extraction database death discharge discharge rate Efficacy eligible hazard hazard ratio hospitalized COVID-19 patient hospitalized COVID-19 patients IL-6 IL-6 inhibitor IL-6 inhibitors individual inhibitor inhibitors Inteleukin-6 intubation Kaplan-Meier curve meta-analyses Meta-analysis outcome Patient patient data patients Randomized control trials Randomized controlled trial randomized trial randomized trials Ratio RCTs reduce reduce mortality risk risk of death significantly SOC. Standard of care synthesis systematic review the mean the MEDLINE Trial two group two groups was performed [DOI] 10.1016/j.ejim.2022.04.004 PMC 바로가기 [Article Type] Meta-Analysis
Can nebulised HepArin Reduce morTality and time to Extubation in patients with COVID-19 Requiring invasive ventilation Meta-Trial (CHARTER-MT): Protocol and statistical analysis plan for an investigator-initiated international meta-trial of prospective randomised clinical studies분무형 HepArin이 침습적 인공호흡이 필요한 COVID-19 환자의 사망률과 발관까지의 시간을 줄일 수 있습니까?Article Published on 2022-07-012022-09-11 Journal: British Journal of Clinical Pharmacology [Category] COVID19(2023년), SARS, 임상, [키워드] Activation alveolar fibrin Analysis Anti-inflammatory ARDS blinded Can clinical study clinical trial Coagulation controlled clinical trials country COVID-19 COVID-19 pneumonia dataset days alive defined Effect endpoints Evidence extubation FIBRIN FIVE heparin hypoxaemic respiratory failure Infection Inhaled International invasive ventilation investigator-initiated Laboratory limit lung Lung injury mammalian cells meta-trial Microvascular thrombosis nebulised heparin open label pandemic patient data patients with COVID-19 Placebo placebo-controlled Pneumonia Prevent Primary outcome progression randomised randomised controlled randomised study RCT receive Respiratory failure resulting SARS SARS-CoV-2 SARS-CoV-2 virus standard care Statistical analysis plan the SARS-CoV-2 virus therapy thrombosis unfractionated heparin unfractionated heparin. ventilator-free day Ventilator-free days with COVID-19 [DOI] 10.1111/bcp.15253 PMC 바로가기 [Article Type] Article
Data-driven quality improvement program to prevent hospitalisation and improve care of people living with coronary heart disease: Protocol for a process evaluation관상 동맥 심장 질환 환자의 입원을 예방하고 치료를 개선하기 위한 데이터 기반 품질 개선 프로그램: 프로세스 평가 프로토콜Article Published on 2022-07-012022-09-11 Journal: Contemporary clinical trials [Category] 임상, [키워드] acceptability approach cardiovascular cardiovascular disease Care change clinical Cluster collected commitment complex components Controlled trial COVID-19 pandemic data data-driven determine Efficiency element ENhance feasibility finding heart disease hospitalisation hospitalisations identify implementation IMPROVE Intervention knowledge Mixed-method research multidimensional New offer patient data Prevent primary care Process process evaluation protocol Qualitative qualitative data Quality Quality improvement Quantitative data randomised controlled trial reduce registry Satisfaction secondary prevention Secondary prevention. utility [DOI] 10.1016/j.cct.2022.106794 PMC 바로가기 [Article Type] Article
Clinical variants of myocardial involvement in COVID-19-positive patients: a cumulative experience of 2020COVID-19 양성 환자에서 심근 침범의 임상적 변이: 2020년 누적 경험Review Published on 2022-07-012022-09-11 Journal: Heart failure reviews [Category] 변종, [키워드] age analyzed Aortic pulsatility index appear Cardiac tamponade Cardiogenic shock Cardiomyopathy caused clinical clinical manifestation clinical manifestations Combination coronavirus COVID-19 COVID-19 patient COVID-19 patients cumulative decrease develop diagnosed died effusion Google Scholar heart heart failure Injury involvement with less LVEF males moderate Mortality myocardial injury myocardial involvement myocarditis occur Older outcome Patient patient data patients pericardial effusion proportion reported searched Shock survived syndrome Takotsubo. tamponade troponin variant [DOI] 10.1007/s10741-021-10129-2 PMC 바로가기 [Article Type] Review
Effects of SARS-CoV‑2 infections on inpatient mortality of geriatric patients after proximal femoral fracture surgerySARS-CoV-2 감염이 근위 대퇴골 골절 수술 후 노인 환자의 입원 사망률에 미치는 영향Article Published on 2022-07-012022-09-11 Journal: Orthopädie (Heidelberg, Germany) [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition age Alter caused clinic Combination conducted coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 Critical Data analysis death Deceased demonstrated died disease Disease progression Effect English evaluated Femoral neck fracture Fracture fractures geriatric patients Geriatrics greater Healthcare system Hospitalization immune increasingly infected patients information Mann-Whitney U test Mortality mortality rate older patient Patient patient data patients PCR test performed Pertrochanteric femoral fracture positive positive correlation positive test result proximal Proximal femoral fracture rehabilitation Retrospective analysis SARS-CoV‑2 SARS-CoV‑2 infection SARS-CoV‑2. severe acute respiratory syndrome Coronavirus significant difference skilled nursing facility student Student's t test survivor T Test Tage test result tested the patient transfer trauma Trauma Center treated two group two groups vaccination was performed [DOI] 10.1007/s00132-022-04268-z PMC 바로가기 [Article Type] Article
Preparing for the next pandemic via transfer learning from existing diseases with hierarchical multi-modal BERT: a study on COVID-19 outcome prediction Research Published on 2022-06-242022-10-05 Journal: Scientific Reports [Category] 바이오마커, 치료법, [키워드] Admission Analysis approach baseline Biomarker Clinical characteristics clinical note COVID-19 Critical Developing diagnostic disease disorder early response electronic healthcare record Hierarchical Infectious disease information knowledge Laboratory tests methodology outcome outcomes pandemic Pandemics Patient patient data Predictive model Preparing prevalent risk factor sub-cohort transfer [DOI] 10.1038/s41598-022-13072-w [Article Type] Research
An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran Research Published on 2022-06-222022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료법, [키워드] affected age alcohol alcohol poisoning all age group Analysis children COVID-19 COVID-19 epidemic COVID-19 outbreak COVID-19 pandemic COVID‐19 diagnosed ethyl alcohol evaluate evaluated hospital Hospital admission Hospitalized incidence increases in Interrupted Iran mental health methanol methyl alcohol Mortality non-toxic occurred outbreak pandemic Patient patient data patients resulting significant increase significantly higher Tehran Toxicity Treatment trend was increased [DOI] 10.1038/s41598-022-14799-2 [Article Type] Research
Protocol for a sequential, prospective meta-analysis to describe coronavirus disease 2019 (COVID-19) in the pregnancy and postpartum periods임신 및 산후 기간에 코로나바이러스 질병 2019(COVID-19)를 설명하기 위한 순차적, 전향적 메타 분석을 위한 프로토콜Article Published on 2022-06-162022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, meta-analysis, SARS, [키워드] Adolescent age aggregate Analysis approach best Child contribute coronavirus disease country COVID-19 epidemiological estimates generate group Health health facilities Health Organization include investigator investigators knowledge Local Maternal meta-analyses meta-analysis Meta-analysis National outcomes pandemic patient data PMA pregnancies Pregnancy pregnant primary analysis protocols question reproductive Research Result SARS-COV-2 infection steering committee systematic review These data threshold while WHO with COVID-19 women working World Health Organization [DOI] 10.1371/journal.pone.0270150 PMC 바로가기 [Article Type] Article
Outcomes of acute limb ischemia in COVID-19Research article Published on 2022-06-012022-10-05 Journal: Journal of vascular surgery [Category] 진단, [키워드] Acute limb ischemia acute renal failure acute respiratory syndrome analyses arterial thromboembolism assisted ventilation baseline Care caused classification cohort characteristics collected Comorbidities Comorbidity complications Consequences coronavirus coronavirus disease COVID-19 defined demographics determine develop diagnostic event events exacerbate Health hospitalized patient identify Infection inflammatory cascade Ischemia less limb mental health Mortality Myocardial infarction objective organization outcome Patient patient data patients with COVID-19 provide Respiratory failure Result SARS-CoV-2 Sepsis significantly significantly higher significantly more stroke the United State thrombosis variables was performed were used with COVID-19 worse prognosis [DOI] 10.1016/j.jvs.2022.04.038 [Article Type] Research article
Endodontic Specialists’ Practice During the Coronavirus Disease 2019 Pandemic: 1 Year after the Initial OutbreakObservational Study Published on 2022-06-012022-10-04 Journal: Journal of endodontics [Category] 임상, [키워드] 95% CI 95% confidence interval analysis change changes in Characteristics comparable coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic demographic determine diagnostic disease Endodontic Endodontics female increase in initial less logistic regression model management multiple logistic regression nonsurgical root canal treatment Odds ratio older patient outbreak Pain parameters Patient patient data Practice practice management. reported returned reversed root canal specialist Treatment were used Year [DOI] 10.1016/j.joen.2022.03.004 PMC 바로가기 [Article Type] Observational Study