The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA virusesArticle Published on 2022-11-072022-11-16 Journal: EMBO Reports [Category] SARS, 변종, [키워드] Antiviral approach cell line Complexes CRISPR DDX42 DDX42 DEAD-box RNA helicase Depletion DNA dominant-negative elements expression Helicase HIV-1 HIV-1 infection identify immunoprecipitation in vitro increase Infection inhibit inhibitor Interaction intrinsic intrinsic immunity LINE-1 mutant overexpression Perspective primary cells Replication restrict reverse transcription ribonucleoprotein RNA RNA virus RNA viruses RNA-seq analysis SARS-CoV-2 target cells viral infections viral inhibition. viruses [DOI] 10.15252/embr.202154061 PMC 바로가기
Hepatitis B virus (HBV) codon adapts well to the gene expression profile of liver cancer: an evolutionary explanation for HBV’s oncogenic roleArticle Published on 2022-11-012022-11-16 Journal: Journal of microbiology (Seoul, Korea) [Category] B형 간염, COVID19(2023년), SARS, 유전자 메커니즘, [키워드] addition Arm association CAI calculated cells codon adaptation index codon adaptation index (CAI) codon usage correlation evolutionary arms race expressed gene gene expression profile HAV HBV HCC HCV Hepatitis hepatitis viruses Hepatocellular carcinoma hepatocellular carcinoma (HCC) highest Host human genes human tissues initial liver liver cell Lungs oncogenesis oncogenic Perspective relative synonymous codon usage (RSCU). Replication RNA SARS-CoV-2 synonymous translation tRNA Viral proteins Viral RNA virus virus viruses [DOI] 10.1007/s12275-022-2371-x PMC 바로가기
Cov-Net: A computer-aided diagnosis method for recognizing COVID-19 from chest X-ray images via machine visionResearch article Published on 2022-11-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 진단, 치료기술, [키워드] Accuracy Algorithms applied asymmetric backbone build CAD Chest X-ray image Computer aided diagnosis (CAD) conditions Convolution Coronavirus disease 2019 COVID-19 database demonstrated Diagnosis Experimental result feature Feature learning global pandemic Image recognition information machine vision mechanism methodology outperform Perspective practicality recognizing robust selected Symptomatic patients [DOI] 10.1016/j.eswa.2022.118029 [Article Type] Research article
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
Evolution and control of the COVID-19 pandemic: A global perspectiveResearch article Published on 2022-11-012022-10-05 Journal: Cities [Category] 치료기술, [키워드] addition affecting city Combination confirmed case correlation Correlation analysis COVID-19 COVID-19 pandemic Critical Effect effective Factor Factors Geodetector Global increase Influencing factors International investigated key factor Local measure Measures notable outbreak Outbreaks pandemic parameters Perspective progression risk second the epidemic [DOI] 10.1016/j.cities.2022.103907 [Article Type] Research article
Enzymes in the time of COVID-19: An overview about the effects in the human body, enzyme market, and perspectives for new drugsArticle Published on 2022-11-012022-11-15 Journal: Medicinal research reviews [Category] COVID19(2023년), SARS, 치료제, [키워드] addition alanine aminotransferase angiotensin-converting enzyme-2 Aspartate aminotransferase Biomarkers cathepsin caused cholesterol contributed coronavirus COVID-19 drug drugs Effect effective effort enzyme enzyme market Enzymes Infection JAK/STAT pathway lactate dehydrogenase M pro mechanism of action metabolism pandemic Papain-like protease pathway Perspective protease reported Research rising SARS-CoV-2 SARS-COV-2 infection Serine syndrome target enzymes. transmembrane Treatment virus [DOI] 10.1002/med.21919 PMC 바로가기
How the COVID-19 pandemic divides society: Towards a better understanding of differences between supporters and opponents of the COVID-19 pandemic lockdown in GermanyArticle Published on 2022-11-012022-11-16 Journal: Journal of psychiatric research [Category] SARS, 치료기술, [키워드] aggression Anxiety approach Containment measure containment measures Corona Corona lockdown opponents coronavirus COVID-19 COVID-19 pandemic cross-sectional demonstrated Depression depressive symptom Effect Factor GAD-7 Germany Health identify increase in irritability lockdown Mental mental health mental health. Participants Perspective Prevalence Qualitative regression analysis Research worsened [DOI] 10.1016/j.jpsychires.2022.09.001 PMC 바로가기
One-step colorimetric isothermal detection of COVID-19 with AI-assisted automated result analysis: A platform model for future emerging point-of-care RNA/DNA disease diagnosisResearch article Published on 2022-11-012022-10-05 Journal: Talanta [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Accuracy Analysis analyzed approach automated Colorimetric RT-LAMP Complete Concordance COVID-19 COVID-19 testing cycle threshold Detection limit diagnosis of COVID-19 Disease diagnosis DNA downstream ENhance exhibited faster feasibility Interpretation isothermal LAMP-DETR limit machine learning majority observation offer pandemic pathogen performed Perspective platform point-of-care RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity [DOI] 10.1016/j.talanta.2022.123375 [Article Type] Research article
Mathematical modeling to study the impact of immigration on the dynamics of the COVID-19 pandemic: A case study for VenezuelaResearch article Published on 2022-11-012022-10-05 Journal: Spatial and spatio-temporal epidemiology [Category] SARS, 변종, [키워드] Affect affected Asymptomatic carriers basic reproduction number COVID-19 COVID-19 pandemic decrease Epidemiology Evolution FIVE identify Immigration Intervention less mathematical mathematical modeling Mild number of infected outcome pandemic parameter Perspective predict public health SARS-CoV-2 SARS-CoV-2 virus Spread susceptible the disease the SARS-CoV-2 threshold transmission rate Venezuela [DOI] 10.1016/j.sste.2022.100532 [Article Type] Research article
Type D lymphomatoid papulosis with pityriasis lichenoides et varioliformis acuta-like features in a child with parvovirus infection: a controversial diagnosis in the spectrum of lymphoid proliferations: case report and literature reviewArticle Published on 2022-10-282022-11-16 Journal: Italian Journal of Pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Administered Alanine antigenic Aspartate aminotransferase Bilirubin C-reactive protein Case report CD8+/CD30+ cells children clinical response clinical suspicion Critical cytokine profile Cytokines Department Diagnosis differential diagnosis discharged disease disorder Emergency erythematous feature Fever histological history Hospitalized IFN-γ IL-10 IL-6 immunoglobulin M infectious agent infiltration introduced Laboratory test lesion lesions limits literature review lymphoid lymphomatoid Lymphomatoid papulosis lymphoproliferative Lymphoproliferative cutaneous disorders marker mechanism monoclonal morphologically necrotic Parvovirus parvovirus B19 pathogenic Perspective phenotype pityriasis lichenoides et varioliformis acuta. polymerase chain reaction positive response proliferation Rash recorded regions reported representing returned SARS-CoV-2 antigen separated skin lesions steroid Support Symptom systemic corticosteroid T-cell receptor Therapies Treatment Type Type D [DOI] 10.1186/s13052-022-01371-x PMC 바로가기