Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 InfectionsArticle Published on 2024-04-222024-09-05 Journal: Viruses [Category] update2024, [키워드] Antiviral agents coronavirus COVID-19 Drug repurposing pharmacokinetics potency potential efficacy SARS-CoV-2 [DOI] 10.3390/v16040651 PMC 바로가기 [Article Type] Article
Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic ResponsesReview Published on 2024-04-222024-09-05 Journal: Viruses [Category] update2024, [키워드] COVID-19 hemagglutination hemagglutinin esterase microvascular occlusion pharmacokinetics red blood cell SARS-CoV-2 sialic acid Spike protein [DOI] 10.3390/v16040647 PMC 바로가기 [Article Type] Review
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stabilityAntiviral Agents Published on 2024-04-212024-09-05 Journal: Med Instrum [Category] update2024, [키워드] antiretroviral resistance Antiviral agents antiviral pharmacology Drug discovery HIV pharmacokinetics preclinical drug studies protease [DOI] 10.1128/aac.01373-23 PMC 바로가기 [Article Type] Antiviral Agents
Safety, efficacy, and pharmacokinetics of nirmatrelvir and ritonavir in patients with severe COVID-19 and renal impairment: A case reportCase Report Published on 2024-03-122024-09-05 Journal: Heliyon [Category] update2024, [키워드] Nirmatrelvir/ritonavir pharmacokinetics severe COVID-19 patients severe renal impairment [DOI] 10.1016/j.heliyon.2024.e28069 PMC 바로가기 [Article Type] Case Report
SAR, Molecular Docking and Molecular Dynamic Simulation of Natural Inhibitors against SARS-CoV-2 Mpro Spike ProteinArticle Published on 2024-03-042024-09-05 Journal: Molecules [Category] update2024, [키워드] COVID-19 density functional theory (DFT) molecular docking (MD) Molecular dynamics simulation pharmacokinetics structure–activity relationship (SAR) [DOI] 10.3390/molecules29051144 PMC 바로가기 [Article Type] Article
An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular EffectsReview Published on 2024-01-182024-09-05 Journal: Molecules [Category] update2024, [키워드] Anti-inflammatory antioxidant cannabidiol CBD cellular effects pharmacokinetics [DOI] 10.3390/molecules29020473 PMC 바로가기 [Article Type] Review
A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studiesarticle Published on 2024-01-062024-09-05 Journal: European heart journal. Cardiovascular pharmacothe [Category] update2024, [키워드] furosemide heart failure intravenous Pharmacodynamics pharmacokinetics Subcutaneous [DOI] 10.1093/ehjcvp/pvad073 PMC 바로가기 [Article Type] article
Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug DeliveryReview Published on 2023-12-292024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] cell-free therapeutics Extracellular vesicles lipid bilayer vesicles nano-biocarriers pharmaceutical applications/drug delivery Pharmacodynamics pharmacokinetics [DOI] 10.3390/ijms25010485 PMC 바로가기 [Article Type] Review
Ibrutinib Efficacy, Safety, and Pharmacokinetics in Chinese Patients with Relapsed or Refractory Waldenström’s Macroglobulinemia: A Multicenter, Single-Arm, Phase 4 StudyOriginal Research Published on 2023-12-112024-09-04 Journal: Advances in therapy [Category] 대상포진, [키워드] Chinese patients Efficacy Ibrutinib pharmacokinetics Relapsed/refractory Safety Waldenström’s macroglobulinemia [DOI] 10.1007/s12325-023-02720-w PMC 바로가기 [Article Type] Original Research
Achillea millefolium : Mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerabilityReview Article Published on 2023-11-302024-09-05 Journal: Heliyon [Category] update2024, [키워드] Achillea millefolium Drug interactions mechanism of action Pharmacodynamics pharmacokinetics Toxicity [DOI] 10.1016/j.heliyon.2023.e22841 PMC 바로가기 [Article Type] Review Article