Overcoming COVID-19 disruptions: Innovations in product provision in a multi-national clinical trial among cisgender men, transgender men and transgender women in five countriesShort communication Published on 2022-08-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 임상, [키워드] administration affected Alternative dispensing method alternative method clinical clinical trial Compliance country COVID-19 COVID-19 pandemic FIVE handling Innovation men pandemic participant Participants preferences preserved procedure protocol Randomized receive receiving rectal Research sequence Standard study participant Study product provision Trial women [DOI] 10.1016/j.conctc.2022.100930 [Article Type] Short communication
Twenty years of investigation with the case of prosopagnosia PS to understand human face identity recognition. Part I: FunctionResearch article Published on 2022-08-012022-10-05 Journal: Neuropsychologia [Category] 비임상, [키워드] Brain build cause cortical diagnostic disorder Face identity recognition facial function Holistic perception identity impairment include individual information Injury mandatory memory Part performed preserved Prosopagnosia Prosopdysgnosia PS recognize Single case specificity tested to define unique Visual recognition [DOI] 10.1016/j.neuropsychologia.2022.108278 [Article Type] Research article
Characterization of compliance phenotypes in COVID-19 acute respiratory distress syndromeObservational Study Published on 2022-08-012022-10-05 Journal: BMC Pulmonary Medicine [Category] 임상, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome ARDS association characterization Cohort collected Compliance compliant lungs coronavirus COVID-19 COVID-19 disease criteria dependent on diagnosis of COVID-19 disease distress driving End-Expiratory Pressure enrolled evaluated Evolution four group greater group groups Hypothesis Hypoxemia ICU ICUs identify IMPROVE initial intensive care lower quartile lung Lung compliance mechanically ventilated patient median Oxygenation PaO parameter Patient patients with COVID-19 PEEP phenotype preserved prone prone positioning prospective observational study quartile relationship respiratory Respiratory mechanics Respiratory system SARS Coronavirus significantly single-center static compliance syndrome tested the disease [DOI] 10.1186/s12890-022-02087-8 PMC 바로가기 [Article Type] Observational Study
Six-Month Follow-Up of Immune Responses after a Rapid Mass Vaccination against SARS-CoV-2 with BNT162b2 in the District of Schwaz/AustriaSchwaz/Austria 지역에서 BNT162b2를 사용한 SARS-CoV-2에 대한 신속한 대량 백신 접종 후 면역 반응의 6개월 추적Article Published on 2022-07-272022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] age Analysis antibody Antibody Response B-cell response B.1.351 Beta BNT162b2 carried correlated COVID-19 detect District enrolment evaluate immune response immune responses Infection mass mass vaccination natural infection new SARS-CoV-2 no correlation outbreak participant participated preserved provide Rapid reduction in response robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections second dose Seropositivity Serum level serum levels specific antibodies spring study participant subject Support T cell T cell response T cell responses T-cell Response the District the SARS-CoV-2 vaccination variant waned was measured [DOI] 10.3390/v14081642 PMC 바로가기 [Article Type] Article
Post-vaccination T cell immunity to omicron오미크론에 대한 백신 접종 후 T 세포 면역Review Published on 2022-07-262022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] Antibody neutralization Antigen caused Clinical studies clinical study COVID-19 COVID-19 vaccine COVID-19 vaccines disease dominant Effect Effectiveness Evidence Heterologous homologous Immunity memory response Memory responses omicron Omicron variant parental Population Post-vaccine Predictive preserved Protective reactivity regimens replaced robust SARS Coronavirus SARS coronavirus 2 SARS-CoV-2 specimen T cell Vaccine [DOI] 10.3389/fimmu.2022.944713 PMC 바로가기 [Article Type] Review
COVID-19 related acute necrotizing encephalopathy with extremely high interleukin-6 and RANBP2 mutation in a patient with recently immunized inactivated virus vaccine and no pulmonary involvement최근 면역 불활화 바이러스 백신을 접종하고 폐 침범이 없는 환자에서 매우 높은 인터루킨-6 및 RANBP2 돌연변이를 갖는 COVID-19 관련 급성 괴사성 뇌병증Case Reports Published on 2022-07-232022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Acute kidney injury Acute necrotizing encephalopathy ADE affecting alteration Analysis antibody blood pressure blood-brain barrier body temperature bpm Brain caused Celsius characteristic Chest Chest radiograph Clinical course Coma Computerized tomography consciousness COVID-19 COVID-19 vaccine cytokine cytokine signaling Cytokine storm Cytokines delta variant Encephalopathy examination Factor gene analysis heart rate hemorrhage hepatic failure heterozygous Hypothesis IL-6 immune response immunized inactivated Inactivated vaccine incidence of COVID-19 infiltration interleukin-6 lesion minute Missense mutation mitochondrial Mitochondrial function Mutation Necrosis oxygen oxygen saturation Pathogenesis Patient Potential treatment predictor preserved Previous studies Prognostic factor pulmonary disease pulmonary involvement pyelonephritis Ranbp2 RANBP2. reported respiratory respiratory rate role SARS-CoV-2 SARS-CoV2 infection Seizure Septic shock Sequencing Serum IL-6 Sinopharm Stupor Vaccine viral entry virus whole genome Whole genome sequencing [DOI] 10.1186/s12879-022-07610-0 PMC 바로가기 [Article Type] Case Reports
Omicron BA.1 Mutations in SARS-CoV-2 Spike Lead to Reduced T-Cell Response in Vaccinated and Convalescent IndividualsSARS-CoV-2 스파이크의 Omicron BA.1 돌연변이는 백신 접종 및 회복기 개인의 T-세포 반응 감소로 이어집니다Article Published on 2022-07-192022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] alleles BNT162b2 BNT162b2 vaccine CD4 CD4+ T-cell CD4+ T-cell epitopes cellular immunity circulating cross-reactive cross-reactivity elicited Epitopes escape facilitated help HLA HLA class II HLA class II alleles HLA motif prediction immune Immune escape immunodominant epitope immunodominant epitopes individual infect loss of memory memory monitoring motif mRNA mRNA-based Mutation mutations natural infection Neutralizing antibodies omicron Omicron BA.1 variant predict predicted preserved reactivity response SARS-CoV-2 SARS-CoV-2 immunity selected spike Spike protein spike-protein strain T cell T cells T-cell T-cell epitope T-cell epitopes T-cell Response T-cell responses the spike protein vaccination variant virus variant virus variants [DOI] 10.3390/v14071570 PMC 바로가기 [Article Type] Article
Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273SARS-CoV-2의 면역 역학은 면역 억제된 류마티스 관절염 또는 mRNA-1273 예방 접종을 받은 다발성 경화증 환자를 경험했습니다.Article Published on 2022-07-152022-09-12 Journal: eLife [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] absence acute respiratory syndrome affected analyzed anti-CD20 antibody Autoimmune Autoimmune disease Autoimmune diseases B cell response benefit CD4 CD8 Cell cellular cellular immunity central memory circulating condition coronavirus COVID-19 COVID-19 mRNA vaccine development disease Disease activity European European Commission first vaccination flow cytometry follicular HCs healthy control Horizon Human humanized humoral Humoral immunity IgG immune immune response Immunity immunology Immunosuppressant immunosuppressants Immunosuppressed increased risk Infection Inflammation leadership longitudinal marker Medicine methotrexate Moderna monoclonal antibody monotherapy mRNA mRNA-1273 MTX multiple sclerosis Netherland organization outcome Patient patients treated preserved recall Research resulting rheumatoid arthritis SARS-CoV-2 second vaccination shielding significantly supported suppress sustained T cell T cell response T cells T helper the SARS-CoV-2 treated Treatment union vaccination Vaccine vulnerable patients whole blood sample [DOI] 10.7554/eLife.77969 PMC 바로가기 [Article Type] Article
Cardiovascular subphenotypes in patients with COVID-19 pneumonitis whose lungs are mechanically ventilated: a single-centre retrospective observational studyObservational Study Published on 2022-07-012022-10-04 Journal: Anaesthesia [Category] 임상, [키워드] acute respiratory distress acute respiratory distress syndrome age aligned Analysis cardiovascular Clinical characteristics clinical outcomes cohort study conducted echocardiographic ICU patient impairment IQR Latent latent class lung male mechanically ventilated mechanism median moderate mortality rate mortality rates outcomes parameters pathophysiology Patient patients with COVID-19 performed preserved Prone ventilation retrospective right ventricular dysfunction right ventricular failure syndrome transthoracic echocardiography Treatment response Unsupervised clustering variable variables ventricular ventricular dysfunction with COVID-19 [DOI] 10.1111/anae.15700 PMC 바로가기 [Article Type] Observational Study
Impact of breakthrough COVID-19 cases during the omicron wave on vascular health and cardiac autonomic function in young adults오미크론파 중 획기적인 COVID-19 사례가 젊은 성인의 혈관 건강 및 심장 자율 기능에 미치는 영향Article Published on 2022-07-012022-09-11 Journal: American journal of physiology. Heart and circulat [Category] COVID19(2023년), SARS, 변종, [키워드] Adults age appear arterial Arterial stiffness autonomic Breakthrough infection cardiac baroreflex sensitivity Cardiovascular health Control COVID-19 COVID-19 case detrimental Diagnosis endothelial endothelial function females flow-mediated dilation group Health healthy heart rate heart rate variability hyperemia Impact impairment investigated less macro measure not different omicron Omicron variant preserved pulse Pulse wave pulse wave velocity reactive reactive hyperemia Research sensitivity severe complications shown These data Variability variant Vascular was determined were assessed with COVID-19 [DOI] 10.1152/ajpheart.00189.2022 PMC 바로가기 [Article Type] Article