Potential protective effect against SARS-CoV-2 infection by APOE rs7412 polymorphismAPOE rs7412 다형성에 의한 SARS-CoV-2 감염에 대한 잠재적 보호 효과Article Published on 2022-05-042022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] age allele anthropometry ApoE association caused characterized Clinical outcome concerning coronavirus correction Course COVID-19 COVID-19 infection environmental factor Factor Genetic genetic determinant genetic factors Genetic variant genotyped global public health global public health emergency Increasing Infection Inflammation men metabolism multiple comparisons obesity pandemic polymorphism Potential priority protective effect resulting SARS-CoV-2 coronavirus SARS-COV-2 infection severity severity of COVID-19 statistically significant the SARS-CoV-2 Volunteer women [DOI] 10.1038/s41598-022-10923-4 PMC 바로가기 [Article Type] Article
Effective Reduction of SARS-CoV-2 RNA Levels Using a Tailor-Made Oligonucleotide-Based RNA Inhibitor맞춤형 올리고뉴클레오티드 기반 RNA 억제제를 사용한 SARS-CoV-2 RNA 수준의 효과적인 감소Article Published on 2022-03-252022-09-11 Journal: Viruses [Category] SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral agents caused cellular coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Efficiency inhibitor lack Level lung cell lines management oligonucleotide oligonucleotide-based RNA inhibitor. pandemic patients hospitalized priority public health RdRP reducing RNA RNA levels RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus therapeutic with COVID-19 [DOI] 10.3390/v14040685 PMC 바로가기 [Article Type] Article
COVID-19 mortality in Italy varies by patient age, sex and pandemic wave이탈리아의 COVID-19 사망률은 환자의 연령, 성별 및 유행성 유행에 따라 다릅니다.Article Published on 2022-03-172022-09-11 Journal: Scientific Reports [Category] SARS, 바이오마커, 치료기술, [키워드] affected age Analysis analyzed caused coronavirus disease Coronavirus disease-19 country COVID-19 COVID-19 mortality database death Deceased diagnosed Diagnosis Epidemic European Factor female First wave group higher risk Hospitalization Hospitalized Infection Italian Italy lower risk Male sex management Mortality mortality rate National Older pandemic Patient priority proportions risk factor SARS-CoV-2 Sex variable with COVID-19 [DOI] 10.1038/s41598-022-08573-7 PMC 바로가기 [Article Type] Article
Risk of Reinfection After Seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Population-based Propensity-score Matched Cohort Study중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)로의 혈청전환 후 재감염 위험: 인구 기반 성향 점수 일치 코호트 연구Article Published on 2022-03-012022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age antibody BMI body mass body mass index Clinical practice conducted controls coronavirus coronavirus 2 COVID-19 Effectiveness Follow-up follow-up period Gender hazard health authorities Health authority help immune response immunodeficiency incidence individual Infection infection rate Matched pandemic participant Participants positive Primary outcome priority protection reduction in Reinfection respiratory retrospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 test selected Seroconversion serological serological assays seronegative seropositive individual seropositive individuals seropositive participants seropositive subject seropositive subjects seroprevalence survey Serosurvey smoking status Standard deviation Switzerland Vaccine [DOI] 10.1093/cid/ciab495 PMC 바로가기 [Article Type] Article
BEMD-3DCNN-based method for COVID-19 detectionBEMD-3DCNN 기반 COVID-19 탐지 방법Article Published on 2022-03-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] 3DCNN analyzed backbone BEMD block can not classification Context-aware attention. coronavirus COVID-19 COVID-19 virus current dataset decomposition deep learning detect detection system diagnostic effective experiment experiments followed by help include information information processing input Medical imaging mode outbreak patients pneumonia cases positive priority PROTECT Research robust selected Spread virus Wuhan Wuhan, China X-ray [DOI] 10.1016/j.compbiomed.2021.105188 PMC 바로가기 [Article Type] Article
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmissionSARS-CoV-2 유입 및 전파 방지를 위한 검역 조치의 게놈 평가Article Published on 2022-02-232022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] Clusters Contact country Effectiveness England evaluated event explained Genome identify index case index cases International measure Mitigation onward transmission Prevent priority quarantine Quarantine period reduces required return returned SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 transmission summer Transmission Travel unique [DOI] 10.1038/s41467-022-28371-z PMC 바로가기 [Article Type] Article
A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in miceThermothelomyces heterothallica의 조작된 곰팡이 균주에서 발현된 재조합 SARS-CoV-2 수용체 결합 도메인은 마우스에서 기능적 면역 반응을 유도합니다Article Published on 2022-02-162022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] C1 Cellular immune response core protein COVID COVID-19 pandemic domain effective vaccine Effective vaccines expressed expression functional immune response fungal HBV hepatitis B Hepatitis B virus humoral immune immune responses immunogenicity induce intrinsic knowledge mice Neutralizing antibodies pathogen platform priority Protein RBD RBD domain Receptor-binding domain S protein S1 subunit SARS CoV SARS CoV-2 SARS-CoV-2 Scientific community Support target the S1 subunit Vaccine Viral Viral protein [DOI] 10.1016/j.vaccine.2022.01.007 PMC 바로가기 [Article Type] Article
Risk Factors for Severe COVID-19 in Children: A Systematic Review and Meta-Analysis소아에서 심각한 COVID-19의 위험 요소: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-072022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval achievement acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Adults age article Asthma children children with COVID-19 chronic lung disease chronic lung diseases Clinical course Comorbidities Comorbidity contagious coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria Critical illness database death Decision making diabete diabetes disease disorder disorders Enrollment Factor heart disease help high risk Hospital admission Hospitalization hospitalizations Immunocompromised immunocompromised status Infant infected with SARS-CoV-2 intensive care intensive care unit admission Invasive mechanical ventilation Lung disease Meta-analysis Neonate neurologic obesity outcome Premature Prematurity Prevalence priority review risk risk factor Risk factors risk ratio risk stratification SARS-CoV-2 SARS-COV-2 infection screened Seizure severe COVID-19 subgroup analysis systematic review vaccination vaccination rate variant variants was performed [DOI] 10.3346/jkms.2022.37.e35 PMC 바로가기 [Article Type] Meta-Analysis
Rationing of a scarce life-saving resource: Public preferences for prioritizing COVID-19 vaccinationArticle Published on 2022-02-012023-07-07 Journal: Health Economics [Category] COVID19(2023년), [키워드] COVID-19 discrete choice experiment distribution Efficiency equity Justice priority public preferences scarcity Vaccine [DOI] 10.1002/hec.4450 PMC 바로가기
Epidemiology of emergency ambulance service calls related to COVID-19 in Scotland: a national record linkage studyOriginal Research Published on 2022-01-282022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] COVID-19, SARS, [키워드] Ambulance ambulance service benefit change clinical care Clinical guidelines clinician cohort study collected COVID-19 COVID-19 in patient COVID-19 negative COVID-19 positive patient death diagnosed dispatch exceeded Health Service identify introduced Mortality mortality rate National NHS outcome pathway Patient positive Positive predictive value PPE presenting priority Result retrospective SAS Scottish service supplementary material Support Symptom System with COVID-19 [DOI] 10.1186/s13049-022-00995-6 PMC 바로가기 [Article Type] Original Research