Impact of tenofovir on SARS-CoV-2 infection and severe outcomes among people living with HIV: a propensity score-matched studySARS-CoV-2 감염 및 HIV 감염자의 심각한 결과에 대한 테노포비르의 영향: 성향 점수 일치 연구Article Published on 2022-07-282022-09-11 Journal: Journal of Antimicrobial Chemotherapy [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Analysis antiretroviral association baseline characteristics Clinical outcome Cohort conducted Cox regression model Diagnosis disease severity emtricitabine evaluated Hospitalization Impact intrinsically logistic regression models management modify Odds ratio outcome outcomes PLWH Propensity score recipient recipients reduced report SARS-CoV-2 SARS-COV-2 infection Spain TDF/FTC tenofovir Tenofovir alafenamide tenofovir disoproxil tenofovir disoproxil fumarate therapeutic with HIV [DOI] 10.1093/jac/dkac177 PMC 바로가기 [Article Type] Article
Six-month sequelae of post-vaccination SARS-CoV-2 infection: A retrospective cohort study of 10,024 breakthrough infections백신 접종 후 SARS-CoV-2 감염의 6개월 후유증: 10,024명의 돌발 감염에 대한 후향적 코호트 연구Article Published on 2022-07-012022-09-11 Journal: Brain, behavior, and immunity [Category] COVID19(2023년), SARS, 변종, [키워드] age Anxiety approved association Bonferroni-corrected Bonferroni-corrected p Breakthrough infection Cohort studies competing composite endpoint contribute controls COVID-19 COVID-19 illness COVID-19 outcomes COVID-19 vaccination COVID-19 vaccine death disease disorder dose effective Electronic health record Electronic health records Features Hair loss Health highlight hospitalisation hypoxaemia ICD-10 ICU admission identify Impact incidence individual infection with SARS-CoV-2 Influenza influenza vaccine Intervention intubation long-COVID lower risk mood omicron Omicron variant outcome outcomes oxygen Oxygen requirement Patient Propensity score psychotic disorder public health recorded renal renal disease representing Respiratory failure retrospective cohort study risk robust SARS-CoV-2 SARS-COV-2 infection Seizures significantly lower sleep disorders Thromboembolism time-to-event analysis USA vaccinated individual vaccination Vaccine vaccine dose vaccine doses variant Venous Thromboembolism Ventilation were assessed [DOI] 10.1016/j.bbi.2022.04.013 PMC 바로가기 [Article Type] Article
Early dexamethasone use as a protective measure in non-mechanically ventilated critically ill patients with COVID-19: a multicenter, cohort study Research Published on 2022-06-132022-10-05 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 1:1 24 hour benefit cohort study consequence COVID-19 COVID19 Critically ill patient debatable Dexamethasone higher odd hospital ICU admission ICUs in-hospital mortality initiated intensive care unit LOS mechanical ventilation Mortality multicenter multicenter cohort study outcome Patient patients with COVID-19 Prevent primary endpoint Propensity score Protective required Respiratory failure SOFA score statistically significant the timing Tocilizumab two group Ventilated ventilated patients was used with COVID-19 [DOI] 10.1038/s41598-022-13239-5 [Article Type] Research
Real-world clinical outcomes of treatment with casirivimab-imdevimab among patients with mild-to-moderate coronavirus disease 2019 during the Delta variant pandemic델타 변이형 대유행 기간 동안 경증에서 중등도의 코로나바이러스 질환 환자를 대상으로 한 카시리비맙-임데비맙 치료의 실제 임상 결과Article Published on 2022-05-092022-09-11 Journal: International Journal of Medical Sciences [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission body temperature Casirivimab casirivimab-imdevimab cigarette smoking clinical Clinical deterioration Clinical outcome contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Delta delta variant demonstrated Deterioration dyslipidemia Effectiveness Efficacy enrolled evaluated Fukushima greater hospital Hospitalization hypertension Imdevimab independent Japan Logistic regression analysis Mild-to-moderate monoclonal antibody monoclonal antibody therapy multivariate multivariate logistic regression analysis Neutralizing obesity Odds ratio Older pandemic Patient Propensity score real-world effectiveness. receiving reduce respiratory SARS-CoV-2 selected severe acute respiratory syndrome Coronavirus significantly lower smoking therapy Treatment [DOI] 10.7150/ijms.71132 PMC 바로가기 [Article Type] Article
Is Telerehabilitation a Viable Option for People With Low Back Pain? Associations Between Telerehabilitation and Outcomes During the COVID-19 PandemicObservational Study Published on 2022-05-052022-10-05 Journal: Physical therapy [Category] 임상, [키워드] 95% CI age association back back pain Care clinics COVID-19 effective Effectiveness episode Frequency functional individual involved low back pain majority no significant difference option outcome outcomes Patient satisfaction physical Physical therapy positive Probability Propensity score proportion receiving rehabilitation reported representing Satisfaction significantly synchronous telerehabilitation therapy Treatment Viable was used were used [DOI] 10.1093/ptj/pzac020 PMC 바로가기 [Article Type] Observational Study
Use of combined treatment of 3rd-generation cephalosporin, azithromycin and antiviral agents on moderate SARs-CoV-2 patients in South Korea: A retrospective cohort study한국에서 중등도 SARs-CoV-2 환자에 대한 3세대 세팔로스포린, 아지트로마이신 및 항바이러스제 병용 치료: 후향적 코호트 연구Article Published on 2022-05-042022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료제, [키워드] adjust administration adverse event Analysis analyzed Antibiotics antiviral agent Antiviral agents association Azithromycin baseline characteristics cephalosporin Clinical outcome Cohort cohorts Combined combined treatment conducted confounding factors COVID-19 COVID-19 patient Cox regression analysis Cox regression method death Efficacy and safety Endpoint endpoints Evidence groups hazard ratio hazard ratios Hospital stay Hydroxychloroquine inclusion criteria Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves laboratory-confirmed Lopinavir Lopinavir/ritonavir low-dose mild to moderate Mild to moderate COVID-19 moderate Moderate COVID-19 moderate COVID-19 patients no significant difference no significant differences not significant Patient performed Prevent Propensity score propensity score matching PSM retrospective cohort study Ritonavir SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients significant differences South South Korea Standard standard supportive care statistical significance Supportive treatment symptom resolution Time to symptom resolution Treatment treatment arm treatment group viral clearance were used [DOI] 10.1371/journal.pone.0267645 PMC 바로가기 [Article Type] Article
Regdanvimab in patients with mild-to-moderate SARS-CoV-2 infection: A propensity score-matched retrospective cohort study경증에서 중등도의 SARS-CoV-2 감염 환자의 레그단비맙: 성향 점수 일치 후향적 코호트 연구Article Published on 2022-05-012022-09-12 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 진단, [키워드] age analyses Analysis applied Clinical efficacy Comorbidities Control control groups COVID-19 CT-P59 Day death disease disease severity Efficacy evaluated high risk Mild-to-moderate neutralizing antibody outcome Patient patients with COVID-19 patients with moderate Pneumonia potential benefit primary endpoint Propensity score proportion PSM reduced reducing reduction regdanvimab required retrospective cohort study risk Safety SARS-CoV-2 SARS-COV-2 infection severe disease significantly significantly lower supplemental oxygen Therapies therapy treated Treatment utility [DOI] 10.1016/j.intimp.2022.108570 PMC 바로가기 [Article Type] Article
Does admission acetylsalicylic acid uptake in hospitalized COVID-19 patients have a protective role? Data from the Spanish SEMI-COVID-19 RegistryObservational Study Published on 2022-04-012022-10-04 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] Acetylsalicylic acid Admission affected Analysis analyzed Cardiovascular disorders collected coronavirus COVID-19 COVID-19 patients determine evaluate evaluated group Health Hospital admission hospitalized COVID-19 patient hospitalized COVID-19 patients ICU ICU admission in-hospital mortality Inflammation intensive care large sample Mortality no difference outcome Patient patients with COVID-19 Pneumonia Propensity score Protective protective role PSM receiving registry retrospective cohort study Spanish symptomatic thrombosis Treatment was performed [DOI] 10.1007/s11739-021-02870-1 PMC 바로가기 [Article Type] Observational Study
Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study암 환자 치료에서 PD-1 억제제의 사용에 대한 COVID-19 백신 접종의 영향 : 실제 연구Observational Study Published on 2022-03-012022-08-31 Journal: Journal for immunotherapy of cancer [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] Adverse adverse event adverse events age All participants Analysis Aside BBIBP-CorV Cancer Chinese hospital Clinical efficacy Common Terminology Criteria Comorbidities Comorbidity conducted conjunction COVID-19 COVID-19 vaccination COVID-19 vaccine criteria defined determine disease disease control Efficacy Efficacy and safety eligible patient enrolled evaluate event female first dose Frequency functional Gender GRADE Grade 1 grade 3 greater immune Immunotherapy Impact implication inhibitor intestinal tract irAE irAEs less liver lung median age median interval metastatic cancer Mild Most patient Most patients multicenter observational study no significant difference no significant differences observational study Participants Patient Patients with cancer PD-1 performance status Propensity score receive receiving recruited reduce reduced reported response response rate screened selected Side effect significant differences Solid statistically status subgroup subgroups the median Therapies therapy Treatment Tumor vaccination Vaccine was used were used [DOI] 10.1136/jitc-2021-004157 PMC 바로가기 [Article Type] Observational Study
Signals were broadly positive for months, but never definitive: the tocilizumab story신호는 몇 달 동안 대체로 긍정적이었지만 결코 확정적이지 않았습니다: tocilizumab 이야기Review Published on 2022-03-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] SARS, 신약개발, 진단, [키워드] accounted analysed appear cohorts Combination conducted confidence interval coronavirus disease COVID COVID-19 COVID-19 disease Critical Critically ill patient death Dexamethasone discrepant results dosage effect size Effectiveness Efficacy Evidence Evidence-based medicine exhibiting Factors heterogeneous Hypothesis in vitro Inclusion inclusion criteria information Invasive mechanical ventilation large sample Meta-analysis MOST observation observational studies observational study occurred pandemic pathway patients treated positive prevented Propensity score Propensity score methods randomized trial RCT RCTs recommendations reduction in risk signal small sample size Standard of care TESEO Tocilizumab treat Treatment treatment guideline [DOI] 10.1016/j.cmi.2021.10.018 PMC 바로가기 [Article Type] Review