Integrating in silico and in vivo approach for investigating the role of polyherbal oil in prevention and treatment of COVID-19 infectionArticle Published on 2022-11-012022-11-15 Journal: Chemico-biological interactions [Category] SARS, 변종, 치료제, [키워드] ACE2 Analysis angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory activity antiviral drug approach approved combating Compound contribute Control COVID-19 COVID-19 infection COVID-19 patients cytokine Efficacy ELIXIR entry of SARS-CoV-2 expression FDA GC-MS group groups hamster hamsters human host in silico in vivo in-silico Infection inhibiting inhibitory effect investigated Lung injury male membrane molecular docking molecular docking studies new SARS-CoV-2 PCR Polyherbal oil Prophylactic Protective real time receptor reduced respiratory diseases SARS-CoV-2 selected significantly Spike protein the SARS-CoV-2 Therapeutics Therapeutics. these compound treat Treatment treatment groups Vaccine variants viral envelope Viral load [DOI] 10.1016/j.cbi.2022.110179 PMC 바로가기
Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promiseReview article Published on 2022-11-012022-10-05 Journal: Nitric oxide : biology and chemistry [Category] SARS, 바이오마커, 변종, 치료제, [키워드] addition anti-inflammatory property Antiviral antiviral action antiviral therapies changes Complication COVID-19 COVID-19 pandemic current Cytokine storm death direct infection endothelial damage Endothelium Evidence function host cell Hydrogen sulfide Hyperinflammatory Infection Inflammation iNOS limit nitric oxide occur platform Protective pulmonary damage rationale reduce Respiratory failure Respiratory system resulting SARS-CoV-2 signaling molecule supportive therapy therapeutic approaches thrombosis Treatment Vascular vasculature viral infection viral infections [DOI] 10.1016/j.niox.2022.08.003 [Article Type] Review article
COVID-19: Vaccines and therapeuticsArticle Published on 2022-11-012022-11-16 Journal: Bioorganic & medicinal chemistry letters [Category] SARS, 변종, [키워드] acute respiratory syndrome approved communicable coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 therapeutics COVID-19 vaccines death deaths disease effective Health highlight Infection Measures New New variants of SARS-CoV-2 Protective reported Research SARS-CoV-2 SARS-CoV-2. Therapeutic strategies Treatment triggered Vaccine variant virus [DOI] 10.1016/j.bmcl.2022.128987 PMC 바로가기
Differential avidity determination of IgG directed towards the receptor-binding domain (RBD) of SARS-CoV-2 wild-type and its variants in one assay: Rational tool for the assessment of protective immunityArticle Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome avidity binding coronavirus IgG IgG RBD Infection LINE mandatory marker mRNA much lower Omicron variant Protective protective immunity RBD reached Receptor-binding domain recom Line SARS-CoV-2 IgG. SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection serology Spike protein the receptor-binding domain vaccination variant wild-type WT SARS-CoV-2 [DOI] 10.1002/jmv.28006 PMC 바로가기
The immune response as a double-edged sword: The lesson learnt during the COVID-19 pandemicArticle Published on 2022-11-012022-11-16 Journal: Immunology [Category] SARS, 변종, [키워드] Asymptomatic breadth cellular Clinical severity COVID-19 COVID-19 pandemic Critical Cross-immunity cytokine Cytokine storm detrimental disease disease severity effort events Evidence feature highlighting immune response Immunopathogenesis Infection Innate immunity pathogen pathogenic processes Protective protective immunity protective immunity. protective role provided public health reducing resulting T-cell immunity the SARS-CoV-2 therapeutic approaches tissue injury Vaccine Viral variants [DOI] 10.1111/imm.13564 PMC 바로가기
Pandemic management requires exposure scienceArticle Published on 2022-11-012022-11-15 Journal: Environment international [Category] SARS, 치료기술, 치료제, [키워드] aerosol aerosol exposure applied Combination COVID-19 COVID-19 transmission effective Environmental and individual exposure control evaluated FFP2 and N95 respirators health care systems Infection Intervention less management Measures Misconception Non-pharmaceutical interventions North opportunity pandemic Pandemics pathway Personal protective equipment Protective public health authority reduce reduction regions risk reduction Spread suppress transmitted Vaccine Ventilation Ventilation and air cleaning Viral aerosol exposure prevention and reduction. virus WHO Wuhan, China [DOI] 10.1016/j.envint.2022.107470 PMC 바로가기
Assessment of dental health care personnel protocol deviations and self-contamination during personal protective equipment donning and doffingArticle Published on 2022-11-012022-11-15 Journal: Journal of the American Dental Association (1939) [Category] SARS, 치료기술, [키워드] abdomen acute respiratory syndrome analysis applied assessment Care cause clinically coronavirus COVID-19 dental Dental health Dental infection control description deviation doffing donning enrolled eye protective devices Face mask Factor Fluorescence fluorescent Frequency gloves, protective Health health, occupational. highest hygiene increased risk Infection involved marker Masks observation participant pathogen transmission Pathogens performed Personal protective equipment PPE PPE donning Protective protocol recorded reduce significantly virus were assessed [DOI] 10.1016/j.adaj.2022.08.004 PMC 바로가기
Hydrothermal deconstruction of single-use personal protective equipment during the COVID-19 pandemicArticle Published on 2022-11-012022-11-15 Journal: Waste management (New York, N.Y.) [Category] SARS, 치료기술, [키워드] acetic adopted ammonia carbon dioxide Concentration Contamination COVID-19 COVID-19 pandemic Fatty acid Hydrothermal deconstruction increase in initial Isolation lowest Masks oxygen Personal protective equipment PPE produced Protective Regulation selected surgical temperature the SARS-CoV-2 virus Transmission TSS was reduced waste waste management Wet Wet oxidation. [DOI] 10.1016/j.wasman.2022.09.006 PMC 바로가기
Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish populationArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] ACE2 ACE2 variant allele frequency Analysis analyzed calculated coding coding variant Cohort conducted contribute COVID-19 database defined filtered Frequency functional Genetic Genome host cell increase infected patient Intronic lack majority National nonsynonymous variant Population populations Protective retrospective risk factor SARS-CoV-2 SARS-COV-2 infection susceptibility Symptom These data TMPRSS2 variant Variant. variants Variation whole-exome sequencing with COVID-19 [DOI] 10.1002/jmv.27976 PMC 바로가기
Immunogenic properties of SARS-CoV-2 inactivated by ultraviolet lightArticle Published on 2022-11-012022-11-15 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Antigen antigenic antigenic variant can be used COVID-19 diagnostic disease effective Effectiveness immunization immunogenic inactivated Inactivated vaccine inactivation induce mice morphology physical Protective reducing mortality SARS-CoV-2 Spread Treatment ultraviolet ultraviolet light Vaccine virus inactivation virus stock virus-neutralizing antibody [DOI] 10.1007/s00705-022-05530-7 PMC 바로가기