Aptasensors for the detection of infectious pathogens: design strategies and point-of-care testingArticle Published on 2022-11-092022-11-15 Journal: Mikrochimica Acta [Category] 치료기술, 치료제, [키워드] approaches aptasensors Bacteria caused contagious coronavirus disease COVID-19 Critical Diagnosis diagnostics Diseases employment Epidemic highlighting implementation Infectious disease infectious pathogens life-threatening mechanisms Nanomaterial-based biosensors nucleic acid pathogen Perspective platform POCT point-of-care Point-of-care testing. Pressing prevalent provided target pathogen viruses [DOI] 10.1007/s00604-022-05533-w PMC 바로가기
Neutralizing response elicited by homologous and heterologous prime booster vaccination against ancestral SARS-CoV-2 B.1, P.1, C.37 and B.1.617.2 variantsArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] analysed B.1 B.1.617.2 BBIBP-CorV booster vaccination ChAdOx1-S Combination country COVID-19 elicited exhibited Gam-COVID-Vac greater Heterologous heterologous vaccination homologous immunized information mRNA-1273 mRNA-1273 vaccines Neutralizing Neutralizing antibodies non-replicative P.1 participant percentage Population protocol protocols provided SARS-CoV-2 second dose serum shortage significantly significantly lower vaccination Vaccination strategies Vaccination strategy Vaccine variant variants of concern. viral vector-based [DOI] 10.1016/j.vaccine.2022.10.021 PMC 바로가기
The human host response to monkeypox infection: a proteomic case series studyArticle Published on 2022-11-082022-11-16 Journal: EMBO Molecular Medicine [Category] 유전자 메커니즘, [키워드] acute phase response Applying Biomarker case sery CFHR1 complement correlation COVID-19 disease severity Diseases endemic area healthy controls Host host response human host Infection Monkeypox virus outbreak overlap Patient plasma plasma protein Protein Proteins proteome proteomic proteomics provided Research similarities suggested suppressed the disease viral infection Viral infection. [DOI] 10.15252/emmm.202216643 PMC 바로가기
COVID-19 vaccine hesitancy in periconceptional and lactating women: a systematic review and meta-analysis protocolArticle Published on 2022-11-072022-11-16 Journal: BMJ Open [Category] meta-analysis, [키워드] Analysis appear approval article caused CNKI Cochrane Library COVID-19 COVID-19 vaccine criteria data extraction determinant discrepancy disease effective Embryology Epidemiology Ethics Evidence gestation heterogeneity higher risk homogeneous indicated lack lactating lactating women lactation Meta-analysis meta-regression observational study outcome outcomes pandemic pandemic of COVID-19 peer-reviewed Pregnancy pregnant pregnant women Prevalence PROSPERO protocol provided receive reproductive Reproductive medicine. required Research resolved subject systematic review vaccination Vaccine hesitancy Web of Science WHO with COVID-19 women [DOI] 10.1136/bmjopen-2021-059514 PMC 바로가기
Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasiaArticle Published on 2022-11-072022-11-16 Journal: Orphanet Journal of Rare Diseases [Category] 유전자 메커니즘, [키워드] analysis Angiogenesis assigned Biomarkers bleeding Blood center double-blind doxycycline Effectiveness ENG Epistaxis Frequency heart failure help hemorrhage Hemorrhagic Hereditary Hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia. HHT IL-6 Inflammatory intravenous limitations Liver disease malformation marker mechanism Michael morbidity no significant difference not significantly different observation pathway Patient Placebo placebo-controlled provided Quality of life Randomized controlled trial Randomly RBC recruited Registered Registration secondary significantly higher stroke telangiectasia therapy Toronto Treatment treatment period Trial VEGF [DOI] 10.1186/s13023-022-02539-8 PMC 바로가기
Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronavirusesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 신약개발, 치료제, [키워드] Analysis common cold Coronaviruses Compound COVID-19 COVID-19 therapeutics cytotoxicity effective gene expression profile globe Heat shock homoharringtonine host cell response host response in silico in vitro modulating other coronavirus pandemic pathway Prevent provided reported SARS-CoV-2 SARS-CoV-2 biology screened severe symptoms tanespimycin target tested unique Vaccine viral infection [DOI] 10.1038/s41598-022-21984-w PMC 바로가기
Novel approach based on GQD-PHB as anchoring platform for the development of SARS-CoV-2 electrochemical immunosensorArticle Published on 2022-11-012022-11-15 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] addition analyzed antibodies antibody approach Blood carbon Carbon nanomaterial Concentration conditions coronavirus spike protein decrease develop domain Dot DPV Electrochemical devices Fever functional Graphene human serum Immunosensors construction. Interaction investigated matrix effect Modification novel PBS performed platform probe Protein provided pulse quantum RBD SARS-CoV-2 selective SEM serum shown was tested was used [DOI] 10.1016/j.aca.2022.340442 PMC 바로가기
Potential intestinal infection and faecal-oral transmission of human coronavirusesArticle Published on 2022-11-012022-11-15 Journal: Reviews in Medical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome circulating close contact common cold coronavirus coronavirus disease COVID-19 described detectable develop Evidence faecal-oral transmission highlight Human human coronavirus human coronaviruses in vitro in vivo Infection intestinal intestinal infection. manifestation MERS MERS-CoV Middle East occur Occurrence Patient Potential proportion provided Respiratory disease respiratory droplet SARS-CoV SARS-CoV-2 shown Spread Symptoms syndrome Transmission Viral RNA [DOI] 10.1002/rmv.2363 PMC 바로가기
Incidence of Guillain-Barré syndrome following SARS-CoV-2 immunization: Analysis of a nationwide registry of recipients of 81 million doses of seven vaccinesArticle Published on 2022-11-012022-11-15 Journal: European journal of neurology [Category] SARS, 변종, 진단, [키워드] 95% CI 95% confidence interval Ad26.COV2-S Administered Admission adverse event adverse events adverse events. age analyzed anti-SARS-CoV-2 vaccine BNT162b2 calculated Campylobacter jejuni ChAdOx1 collected CoronaVac COVID-19 diarrhea died dose doses epidemiological Guillain-barrè syndrome immunization inactivated incidence interquartile range Intravenous immunoglobulin male median Mild mRNA-1273 mRNA-based Patient performed plasma positive provided recipient reported risk SARS-CoV-2 Seven Surveillance survivor symptom onset syndrome tested treated vaccination Vaccine Vaccines variant [DOI] 10.1111/ene.15504 PMC 바로가기
Smartphone-Based Electrochemical Immunoassay for Point-of-Care Detection of SARS-CoV-2 Nucleocapsid ProteinArticle Published on 2022-11-012022-11-15 Journal: Analytical Chemistry [Category] COVID19(2023년), SARS, 치료기술, [키워드] antibody bovine calculated coated with Concentration detection detection efficiency diagnose Diagnosis effective electron transfer facilitate immunoassay lack less limit of detection linear N protein nucleocapsid protein offer point-of-care provided R 2 reduced reducing reported resulting SARS-CoV-2 SARS-CoV-2 N protein serological serum albumin the SARS-CoV-2 transmitted virus transmission [DOI] 10.1021/acs.analchem.2c03606 PMC 바로가기