Renin-angiotensin system blocker and the COVID-19 aggravation in patients with hypertension, diabetes, renal failure, Cerebro-cardiovascular disease, or pulmonary disease: Report by the COVID-19 Registry JapanObservational Study Published on 2022-10-012022-10-05 Journal: Journal of cardiology [Category] 임상, [키워드] ACEi/ARB acute respiratory syndrome Admission Analysis angiotensin-converting enzyme inhibitor ARB Associated factors association blocker chronic obstructive COPD coronavirus coronavirus disease correlation COVID-19 diabetes Diabetes Mellitus disease Disease outcome. Diseases enrolled extracorporeal membrane oxygenation Factor Female patients healthcare healthcare facility hypertension In-hospital death increased risk information intensive care Japan lower risk male Male sex outcome pandemic Patient patients positive Primary outcome Primary outcomes pulmonary disease receptor registry registry data renal renal impairment report risk severe COVID-19 severe renal impairment severity Support Treatment ventilator with COVID-19 [DOI] 10.1016/j.jjcc.2022.04.001 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 spike IgG titres up to 137 days following Comirnaty mRNA COVID-19 vaccination, Israel, February to May 2021Article Published on 2022-10-012022-11-15 Journal: Eurosurveillance [Category] COVID19(2023년), SARS, 진단, [키워드] antibody antibody level baseline characteristics body mass cardiovascular disease Chronic kidney disease chronic obstructive Comorbidity Concentration conducted congestive heart failure coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine cut-off diabete dose Factor female first dose geometric mean GFR glomerular filtration rate GMC GMCs IgG IgG antibodies IgG antibody Immunosuppression Infection Inflammatory bowel disease levels of antibody male mRNA Patient peaked pulmonary disease remained repeated reported resource retrospective cohort study SARS-CoV-2 SARS-CoV-2 spike serological serology solid malignancy the antibody the SARS-CoV-2 titre vaccination were used [DOI] 10.2807/1560-7917.ES.2022.27.40.2100703 PMC 바로가기
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in miceArticle Published on 2022-09-282022-11-15 Journal: Science Translational Medicine [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory syndrome alveolar Antiviral cells chronic disease chronic inflammation clinical recovery collagen composed coronavirus coronavirus disease COVID-19 develop disease severity dysfunction dysregulated EIDD-2801 epithelial fibroblasts fibrosis histologic finding humans identify Immune cell individual Intervention lack lesion longitudinal lung abnormality lymphoid mice mouse-adapted SARS-CoV-2 murine model Nintedanib PASC Pathogenesis pathway Population proliferative provide pulmonary disease reduced regions SARS-CoV-2 SARS-COV-2 infection structures subpleural subset syndrome tissue samples transcriptional virus clearance [DOI] 10.1126/scitranslmed.abo5070 PMC 바로가기
The Variation of Transcriptomic Perturbations is Associated with the Development and Progression of Various DiseasesArticle Published on 2022-09-262022-11-16 Journal: Disease Markers [Category] 유전자 메커니즘, [키워드] activities AIDS AIDS patient Algorithm analyzed applied association atrophic gastritis cardiovascular diseases caused cellular chronic obstructive clinical implication clinically controls COPD correlated correlation COVID-19 patient deficiency defined development digestive disease Disease diagnosis Disease progression Diseases Ejection fraction Endocrine diseases expiratory expression greater Health status heterogeneity ICU immune Infection intensive care investigated involved Kidney diseases liver diseases LVEF malaria mechanical ventilatory support negative correlation Neurological disorders non-ICU patients pathway patients Perturbation presymptomatic Prognosis pulmonary disease pulmonary tuberculosis Regulation respiratory diseases severity significantly syndrome the disease Therapies transcriptome datasets transcriptomic transcriptomic data treated upregulated upregulation Variation variety ventricular Viral load Volume [DOI] 10.1155/2022/2148627 PMC 바로가기
Two-Year Health Outcomes in Hospitalized COVID-19 Survivors in ChinaArticle Published on 2022-09-012022-11-16 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI acute illness Admission age Analysis Anxiety change Chest China chronic obstructive cohort study conducted COVID-19 decrease defined discharge Dyspnea Factor fatigue Follow-up follow-up study follow-up visits Health higher risk hospital hospital discharge Hospitalization hospitalized COVID-19 identify incidence increased risk Infection intensive care IQR longitudinal cohort study male median MOST myalgia Odds ratio omicron outcome Patient patients who survived patients with COVID-19 persistence pulmonary disease questionnaire required resolved severe disease Severity of disease survivor Survivors Symptom symptom burden Symptoms total score variant virus World Health Organization worsening Wuhan, China [DOI] 10.1001/jamanetworkopen.2022.31790 PMC 바로가기
COVID-19 prophylaxis with doxycycline and zinc in health care workers: a prospective, randomized, double-blind clinical trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 치료기술, 치료제, [키워드] Asthma Care chronic obstructive clinical trial Combination combination treatment conducted control groups COVID-19 COVID-19 infection Cycle threshold value decrease demonstrated determine diabete dose double-blind doxycycline Effectiveness Efficacy Health Health care worker hypertension indicated Infection Participants patients with SARS-CoV-2 Placebo polymerase chain prevention of COVID-19 Prophylactic Prophylaxis protective effect pulmonary disease Randomized reduced reverse transcription risk SARS-CoV-2 SARS-COV-2 infection significant decrease therapy Treatment Viral load was measured Zinc [DOI] 10.1016/j.ijid.2022.06.016 PMC 바로가기 [Article Type] Randomized Controlled Trial
An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: The Lancet. Respiratory Medicine [Category] Fulltext, MERS, 임상, [키워드] 1:1 adverse event Analysis Anxiety approach approaches assigned Block randomisation breathlessness chronic obstructive clinically clinics complementary computer-generated conducted COVID COVID-19 eight element English Generalised anxiety disorder groups Health Imperial College London IMPROVE improvement individual intention-to-treat population Intervention Mental mental health MHC outcome measure parallel-group participant participated Patient physical potential participant Primary outcome pulmonary disease qualitative data randomisation randomised controlled trial Randomly recovering from COVID-19 recruited Registered reported Research researcher responses responsible secondary secondary outcome single-blind statistically significant Symptom thematic analysis treatment group Trial unique usual care usual care group Visual Analogue Scale was done were excluded were given [DOI] 10.1016/S2213-2600(22)00125-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Epstein-Barr Virus and Human Herpesvirus-6 Reactivation in Acute COVID-19 PatientsArticle Published on 2022-08-252022-11-15 Journal: Viruses [Category] 치료기술, [키워드] Activation association Autoimmune disorders blood donor Characteristics Coagulopathies Cohort cohorts complex contribute COVID-19 COVID-19 patient detectable disease EBV Epstein-Barr virus Epstein–Barr virus feature fraction Frequency healthy healthy control herpesvirus HHV-6 Hospitalization Hospitalized Human Human Herpesvirus-6 hyperinflammatory responses Infection Inflammation Inflammatory inflammatory disease Inflammatory mediators marker occurred Pathogenesis Patient patients plasma pulmonary disease quantitative PCR Reactivation reported SARS-CoV-2 subset syndrome tested virus with COVID-19 [DOI] 10.3390/v14091872 PMC 바로가기
Testing for coronarvirus disease 2019 before cardiac surgery-safe outcome of infected patients감염된 환자의 심장 수술 안전한 결과 전에 코로나바이러스 질병 2019에 대한 테스트Article Published on 2022-08-242022-09-11 Journal: Journal of Cardiothoracic Surgery [Category] SARS, 치료기술, [키워드] airway Body body mass body mass index cardiac Cardiac surgery chronic obstructive chronic obstructive pulmonary disease coronavirus disease Coronavirus disease 2019 COVID-19 diabetes Diabetes Mellitus diagnosed disease Ejection fraction female gender hospital Hospital staff index infected patient less mass nasopharynx negative test not differ obstructive pulmonary disease operation outbreak outcome pandemic Patient patients patients with COVID-19 PCR PCR testing performed positive COVID-19 positive PCR test postoperative preoperative Preoperative PCR testing. pulmonary disease reduced significantly surgery surgical swabs Symptom Testing Transmission undergo ventricular ventricular ejection virus was recorded with COVID-19 [DOI] 10.1186/s13019-022-01960-1 PMC 바로가기 [Article Type] Article
Database and AI Diagnostic Tools Improve Understanding of Lung Damage, Correlation of Pulmonary Disease and Brain Damage in COVID-19데이터베이스 및 AI 진단 도구는 COVID-19의 폐 손상, 폐 질환 및 뇌 손상의 상관 관계에 대한 이해를 향상시킵니다.Review Published on 2022-08-222022-09-11 Journal: Sensors (Basel, Switzerland) [Category] SARS, 치료기술, [키워드] AI diagnostic Algorithm Algorithms applied article artificial intelligence Brain brain damage caused condition coronavirus disease correlation COVID-19 COVID-19 pandemic damage database databases Diagnosis downloaded Early detection EEG EEGs electroencephalogram evaluated Google Scholar healthcare implication increase in lung lung damage Lung disease Lung diseases Patient pulmonary pulmonary disease recent resource Respiratory system SARS-CoV-2 searched shown systematic review the disease understanding [DOI] 10.3390/s22166312 PMC 바로가기 [Article Type] Review