Corrected QT interval in hospitalized patients with coronavirus disease 2019: Focus on drugs therapy2019년 코로나바이러스 감염증 입원환자 교정 QT 간격: 약물치료를 중심으로Observational Study Published on 2021-07-162022-09-11 Journal: Medicine [Category] SARS, 임상, 치료제, [키워드] 95% CI 95% confidence interval administration Antiviral agents Arbidol Biomarker Campus cardiac injury Chloroquine chloroquine/hydroxychloroquine confirmed COVID-19 case coronavirus disease Coronavirus disease 2019 COVID-19 severity creatine creatine kinase Creatine kinase-MB drug Drug administration Effect exhibited focus fraction hospitalized patient Hydroxychloroquine increased the risk Injury interferon less Lopinavir Lopinavir/ritonavir Mortality Odds ratio Patient patients treated peptide positively correlated Prognosis QT interval QTc QTc interval QTC prolongation receiving risk Ritonavir severity significant effect study cohort therapy treated Treatment troponin I Union Hospital West with COVID-19 Wuhan [DOI] 10.1097/MD.0000000000026538 PMC 바로가기 [Article Type] Observational Study
Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey교정 QT 간격 및 Torsade de Pointes 유도에 대한 COVID-19 약물의 영향: 다기관 국가 조사 결과Multicenter Study Published on 2021-07-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 치료제, [키워드] addressed administration Amiodarone arrhythmia Atazanavir Azithromycin Chloroquine Cohort Combination combination therapy coronavirus coronavirus disease COVID-19 COVID-19 patient Critical death demonstrated during treatment Effect Favipiravir female gender furosemide heart failure hepatic dysfunction hospital hospitalised Hydroxychloroquine hypokalaemia incidence inclusion criteria Iran life-threatening Lopinavir Lopinavir-ritonavir Lopinavir/ritonavir medication medications multicenter National occurred oseltamivir Patient patients predicted Primary outcome Prospective Study QT interval QT prolongation QTc QTC prolongation Remdesivir renal reported Repurposed drug Repurposed drugs Result risk Ritonavir secondary outcome Secondary outcomes Side effect therapy Torsade de Pointes treated Treatment [DOI] 10.1111/ijcp.14182 PMC 바로가기 [Article Type] Multicenter Study
Drug–drug interactions between treatment specific pharmacotherapy and concomitant medication in patients with COVID-19 in the first wave in Spain스페인의 첫 번째 물결에서 COVID-19 환자의 치료 특이 적 약물 요법과 동반 약물 간의 약물 연체 상호 작용Article Published on 2021-06-142022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 임상, 치료기술, 치료법, [키워드] 105 patient 105 patients Admission adverse effects analyzed binomial logistic regression carried Charlson index checked Chemical clinically cohort study Comorbidity Concomitant Concomitant medication concomitant medications conducted COVID-19 drug drug therapy drug–drug interaction drugs during admission Factor First wave hospital Hospital stay hospitalized patient hospitalized patients Hydroxychloroquine identify Infectious diseases Interaction involved Lopinavir Lopinavir/ritonavir mechanism medication Patient patients patients with COVID-19 polypharmacy Prevalence prolongation QTC prolongation resource risk factor Risk factors Ritonavir SARS-COV-2 infection severity single center Spain therapy Treatment University of Liverpool [DOI] 10.1038/s41598-021-91953-2 PMC 바로가기 [Article Type] Article
QT Interval Monitoring with Handheld Heart Rhythm ECG Device in COVID-19 PatientsCOVID-19 환자에서 휴대용 심장 리듬 ECG 장치를 사용한 QT 간격 모니터링Observational Study Published on 2021-06-082022-09-11 Journal: Global Heart [Category] SARS, 임상, 진단, 치료제, [키워드] 6-lead ECG addressed adverse effect Azithromycin baseline Cohort control group COVID-19 COVID-19 patient Device displaying dissemination ECG evaluate evaluated feasibility feasible Follow-up groups handheld ECG healthcare providers healthy heart Hospitalization Hydroxychloroquine ICC increase in interval KardiaMobile KardiaMobile-6L Lopinavir Lopinavir-ritonavir moderate monitoring no differences not differ offer patients Prospective Prospective Study QTc QTC prolongation receiving reliability rhythm Ritonavir significantly significantly lower smart device Therapies time treated ventricular arrhythmia virus was performed [DOI] 10.5334/gh.916 PMC 바로가기 [Article Type] Observational Study
Effect of Hydroxychloroquine on QTc in Patients Diagnosed with COVID-19: A Systematic Review and Meta-AnalysisSystematic Review Published on 2021-05-132022-10-30 Journal: Journal of Cardiovascular Development and Disease [Category] COVID-19, [키워드] addition Chloroquine Combination combination therapy concomitant use coronavirus COVID-19 database Effect heterogeneity hospitalized patient Hydroxychloroquine hydroxychloroquine plus azithromycin In vitro studies inclusion criteria increase in increases in Infection management material medRxiv Meta-analysis numbers of patient Patient patients patients with SARS-CoV-2 prespecified endpoint QTc QTc interval QTC prolongation random effect model review SARS-CoV-2 SARS-COV-2 infection statistically significant systematic review torsades de pointes treat use of hydroxychloroquine was used with COVID-19 ΔQTc [DOI] 10.3390/jcdd8050055 PMC 바로가기 [Article Type] Systematic Review
Longitudinal study based on a safety registry for malaria patients treated with artenimol–piperaquine in six European countries말라리아 환자를 대상으로 아르테니몰-피페라퀸으로 치료한 안전성 등록부를 기반으로 한 종단적 연구, 6개 유럽 국가에서Research Published on 2021-05-082024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] adverse events Artemisinin Artenimol Eurartesim Imported malaria Piperaquine Plasmodium falciparum QTC prolongation Safety [DOI] 10.1186/s12936-021-03750-x PMC 바로가기 [Article Type] Research
What are the risk factors for admission to the pediatric intensive unit among pediatric patients with COVID-19?Commentary Published on 2021-05-032022-10-29 Journal: Italian Journal of Pediatrics [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Admission affected alteration Arrhythmias Asymptomatic Care changes children clinical manifestations Comorbidity coronavirus COVID-19 COVID-19 cases death develop diastolic disease disease severity effective Ejection fraction enzyme Evidence greater highlight Infection Intensive intensive care manifestation manuscript marker mechanical ventilation Mild occur outcome pediatric Pediatric case Pediatric intensive care unit Pediatric patient Predictive Premature QTC prolongation required Respiratory Support risk risk factor SARS-CoV-2 Serum level severe COVID-19 substantial risk susceptibility Treatment ventricular with COVID-19 [DOI] 10.1186/s13052-021-01057-w PMC 바로가기 [Article Type] Commentary
Cardiac Corrected QT Interval Changes Among Patients Treated for COVID-19 Infection During the Early Phase of the Pandemic팬데믹 초기 단계에서 COVID-19 감염 치료를 받은 환자의 심장 교정 QT 간격 변화Research Published on 2021-04-232022-09-12 Journal: JAMA Network Open [Category] MERS, SARS, 진단, [키워드] 12-lead electrocardiogram 95% CI age Analysis analyzed association Azithromycin baseline Black patients cardiac center change Chronic kidney disease clinical factor cohort study Columbia University Columbia University Irving Medical Center COVID-19 COVID-19 infection Critical illness ECG ECGs electrocardiogram elevated elevated lactate dehydrogenase evaluate evaluated exposure finding greater had more Hospitalization Hospitalized hospitalized patients Hydroxychloroquine Importance incidence increase in independent independent of Infection infection with COVID-19 Inflammatory response interval Kidney disease Lactate lactate dehydrogenase mean difference measure men multivariable multivariable analysis multivariable model Multivariable models objective observation period occurred Older participant Patient patients with COVID-19 patients without COVID-19 phase Point prolonged corrected QT interval proportion QT interval QTc QTc interval QTC prolongation receiving Relevance Result SARS-CoV-2 SARS-CoV-2 testing setting torsades de pointes treatment group troponin level virus with COVID-19 [DOI] 10.1001/jamanetworkopen.2021.6842 PMC 바로가기 [Article Type] Research
Coronavirus disease 2019 (COVID-19) and QTc prolongationObservational Study Published on 2021-03-302022-10-27 Journal: BMC Public Health [Category] COVID-19, [키워드] age angiotensin-converting enzyme inhibitor arrhythmia baseline cardiovascular disease Chronic kidney disease Combination comparable congestive heart failure contribute Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients develop diagnosis of COVID-19 drug Ejection fraction End-stage renal disease ESRD hospital Hospitalization Hospitalized Hydroxychloroquine Infection Injury ischemic heart disease less Mortality objective Older Patient preserved QT prolongation QTc QTc interval QTC prolongation Result retrospective two groups USA ventricular virus [DOI] 10.1186/s12872-021-01963-1 PMC 바로가기 [Article Type] Observational Study
Coronavirus disease 2019 (COVID-19) and QTc prolongationObservational Study Published on 2021-03-302022-10-27 Journal: BMC Public Health [Category] Coronavirus, COVID-19, SARS, [키워드] age angiotensin-converting enzyme inhibitor arrhythmia baseline cardiovascular disease Chronic kidney disease Combination comparable congestive heart failure contribute Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients develop diagnosis of COVID-19 drug Ejection fraction End-stage renal disease ESRD hospital Hospitalization Hospitalized Hydroxychloroquine Infection Injury ischemic heart disease less Mortality objective Older Patient preserved QT prolongation QTc QTc interval QTC prolongation Result retrospective two groups USA ventricular virus [DOI] 10.1186/s12872-021-01963-1 PMC 바로가기 [Article Type] Observational Study