Epidemiological and genomic findings of the first documented Italian outbreak of SARS-CoV-2 Alpha variant of concern우려되는 SARS-CoV-2 Alpha 변이체의 이탈리아 최초 발병 사례에 대한 역학 및 게놈 연구 결과Article Published on 2022-06-012022-09-11 Journal: Epidemics [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Abruzzo Alpha variant Alpha VOC Analysis calculated clade Contact diffusion epidemiological data Epidemiology genomic Genomic analysis Genomic surveillance GISAID database identity Italian network outbreak random referred to reproduction Reproduction number SARS-CoV-2 SARS-CoV-2, Alpha variant. sequence sequences subset town transmission parameters VoC [DOI] 10.1016/j.epidem.2022.100578 PMC 바로가기 [Article Type] Article
Prognostic accuracy of inflammatory markers in predicting risk of ICU admission for COVID-19: application of time-dependent receiver operating characteristic curvesCOVID-19에 대한 ICU 입원 위험 예측에서 염증 표지자의 예후 정확도: 시간 종속 수신기 작동 특성 곡선의 적용Observational Study Published on 2022-06-012022-09-11 Journal: The Journal of international medical research [Category] MERS, 바이오마커, 임상, [키워드] 95% CI 95% confidence interval Accuracy Admission approach Ayatollah baseline level baseline levels C-reactive protein C-reactive protein (CRP Care characteristic COVID-19 COVID-19 infection CRP cutoff value evaluate evaluated greater hazard ratio Hospital admission Hospitalization ICU ICU admission Inflammatory marker inflammatory markers intensive care intensive care unit intensive care unit admission Iran lymphocyte Medical Sciences neutrophil Neutrophil-to-lymphocyte ratio NLR observational study occur outcome Patient patients with COVID-19 predictor reached receive receiver operating characteristic receiver operating characteristic curve referred to risk ROC ROC Curve ROC curves severe COVID-19 Severe COVID-19 Infection significantly Stratification time-dependent area under the receiver operating characteristic curve. time-dependent ROC curve university [DOI] 10.1177/03000605221102217 PMC 바로가기 [Article Type] Observational Study
Longitudinal profile of neutralizing and binding antibodies in vaccinated and convalescent COVID-19 cohorts by chemiluminescent immunoassays화학발광 면역분석에 의한 백신 접종 및 회복기 COVID-19 코호트에서 중화 및 결합 항체의 종단 프로필Article Published on 2022-06-012022-09-11 Journal: Immunity, Inflammation and Disease [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] antibodies antibody antibody profile, COVID-19 convalescent Antibody testing binding antibody booster vaccination chemiluminescent immunoassay coefficient coefficient of correlation convalescent correlation COVID-19 COVID-19 cohort diagnostic dose elicited enrolled enzyme evaluate evaluated exhibited extension humoral immune response Humoral immunity IgG Immune status Immunity immunoassay Immunoglobulin Immunoglobulin G inactive Infection Interpretation longitudinal Neutralizing neutralizing antibody no difference priming priming dose Protective RBD RBD IgG referred to risk of COVID-19 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody SARS-CoV-2 RBD SARS-CoV-2 vaccine seroconversion rate serological Serological assay serum surrogate the SARS-CoV-2 therapy threshold trajectory vaccination vaccination schedule Vaccine Volunteer was collected [DOI] 10.1002/iid3.612 PMC 바로가기 [Article Type] Article
Implementation of a Case Investigation and Contact Tracing Program at an Academic Medical Center in New York City뉴욕시 아카데믹 의료 센터에서 사례 조사 및 접촉 추적 프로그램 구현Article Published on 2022-06-012022-09-11 Journal: Academic medicine : journal of the Association of [Category] COVID19(2023년), SARS, 변종, [키워드] Brooklyn Campus center collaboration Contact Contact tracing Control COVID-19 COVID-19 case COVID-19 infections COVID-19 pandemic COVID-19 transmission COVID-19 vaccination Department disease control epicenter Guidance hospitalizations initial investigated investigation limit Mortality New York New York City prevention Program protocol protocols recruited referred to Schools Science severity Spread spring state student Surveillance tracing transitioned university variants waned [DOI] 10.1097/ACM.0000000000004624 PMC 바로가기 [Article Type] Article
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial영국에서 ChAdOx1 nCov-19 또는 BNT162b2 2회 접종 후 3차 추가 접종으로 7가지 COVID-19 백신을 투여한 후 면역원성의 지속성: COV-BOOST 시험의 3개월 분석Clinical Trial Published on 2022-06-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 임상, 진단, [키워드] Ad26 Ad26.COV2.S adenoviral vector adenoviral vector vaccine Analysis anti-Spike IgG antibody AstraZeneca BNT BNT162b2 booster booster dose cellular response Cellular responses ChAd ChAdOx1 ChAdOx1 nCoV-19 Concentration conducted COV-BOOST COVID-19 COVID-19 vaccine Critical death dose doses evaluate Fractional dose geometric mean geometric mean concentration geometric mean ratio GMR GMRs Heterologous boost highest Homologous boost humoral Humoral response immune response immune responses immunogenicity initial janssen long-lasting maintenance median age mRNA mRNA vaccine mRNA vaccines multicentre naïve no significant difference Oxford-AstraZeneca participant persistence Pfizer-BioNTech Phase 2 phase 2 trial randomised referred to response responses SARS-CoV-2 Seven severe disease significant difference significantly higher the vaccine third dose Transmission Trial Vaccine Vaccines variants of concern while [DOI] 10.1016/j.jinf.2022.04.018 PMC 바로가기 [Article Type] Clinical Trial
Characteristics and outcomes of ambulatory patients with suspected COVID-19 at a respiratory referral center호흡기추천센터에서 이동하는 코로나19 의심환자의 특징 및 결과Article Published on 2022-06-012022-09-11 Journal: Respiratory medicine [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory symptom acute respiratory symptoms ambulatory ambulatory patient Ambulatory respiratory infections analyzed Asthma baseline Care characteristics of patient chronic respiratory disease clinic clinical Clinical prediction. Comorbidities Composite COPD COVID-19 COVID-19 diagnosis COVID-19 vaccination CRD demographics diagnose Diagnosis elevated Eosinopenia expiratory febrile FEV forced expiratory volume Gender global pandemic help hospital Laboratory tests logit lymphocytosis male management medical record medications neutrophilia outcome oxygen oxygen saturation Patient patient disposition PCR Positive test predicted Pulmonary function tests R package referred to respiratory respiratory infections respiratory rate risk SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 PCR seeking SPO Symptom temperature variants Vital vital signs vitals Volume was used WBC were used with COVID-19 [DOI] 10.1016/j.rmed.2022.106832 PMC 바로가기 [Article Type] Article
A prospective evaluation of diagnostic performance of a combo rapid antigen test QuickNavi-Flu+COVID19 Ag복합 신속항원 검사 QuickNavi-Flu+COVID19 Ag의 진단 성능에 대한 전향적 평가Article Published on 2022-06-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen antigen test collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Denka detect diagnostic discrepant result discrepant results evaluated immunochromatography Influenza Influenza virus influenza viruses Japan L452R Nasal sample nasal samples nasopharyngeal sample Nasopharyngeal samples pathogen Pathogens PCR positive prevalent QuickNavi-Flu+COVID19 Ag real-time RT-PCR referred to respiratory sample reverse transcription PCR RT-PCR SARS-CoV-2 SARS-CoV-2 detection sensitivities sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity spike mutation study period Swab symptomatic cases Symptomatic patients Tokyo variant [DOI] 10.1016/j.jiac.2022.02.027 PMC 바로가기 [Article Type] Article
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-191차 진료 또는 병원 외래 환자 환경에 있는 환자가 COVID-19에 감염되었는지 확인하기 위한 징후 및 증상Review Published on 2022-05-202022-09-11 Journal: The Cochrane database of systematic reviews [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] 95% CI absence Abstract Accuracy addition Adults age Ageusia Analysis Anosmia applicability artificial intelligence assessment assessments Bern Chain Reaction characteristic checked children clinically clinically suspected clinics Cohort Combination combinations condition Consequences Contact Control coryza cough COVID-19 COVID-19 disease COVID-19 illness COVID-19 pneumonia COVID-19 testing criteria criterion Data collection database dependent on detection rate determine determined by diagnostic Diagnostic accuracy diagnostic test diagnostic tests diagnostic value disease Dyspnoea eligibility eligible emergency department enrolled Evidence excluded fatigue Fever FIVE Gender Health Service Health services help heterogeneity high risk hospital identify increase individual individual symptom Infection Infectious disease information initial investigated life-threatening likelihood ratio Local loss of sense of smell majority mechanism median Meta-analysis Mild Mild COVID-19 disease moderate MOST multivariable no symptom no symptoms nursing homes Older olfactory on children Outpatient outpatients overlapping pair parameter participant Participants Patient PCR Pneumonia polymerase chain polymerase chain reaction positive Presence presenting primary care Probability Prognosis Prospective Study QUADAS-2 random-effect reached receiver operating characteristic recruited reference standard Reference standards referred to reported Repository resolved Result reverse transcription reverse transcription polymerase chain reaction risk of bia ROC RT-PCR Sample size SARS-COV-2 infection selected Selection sense sense of smell sensitivity Sensitivity and specificity SIGN Signs and symptoms sore sore throat specific symptom Specificities specificity Support Symptom Symptoms Taste the disease the epidemic Travel treated University of Bern upper respiratory symptom upper respiratory symptoms were measured with COVID-19 [DOI] 10.1002/14651858.CD013665.pub3 PMC 바로가기 [Article Type] Review
Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 TherapySARS-CoV-2에서 돌연변이를 유발하는 원동력 이해: 돌연변이 에너지와 COVID-19 치료에서 아르기닌 차단제의 역할Article Published on 2022-05-112022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] 3CLpro accelerated ACE2 ACE2 protein Alpha Amino acid amino acids angiotensin Angiotensin receptor blockers angiotensin type1 receptor Angiotensin-converting enzyme anionic antiviral drug arginine assist association Beta binding biphenyl bisartans blocker blockers candidate drug cleavage site cleavage sites complex complexes Computational approaches conformation conformational contribute COVID-19 COVID-19 therapy Critical Delta delta variant driving drug energetics ENhance equilibrium Evolution of SARS-CoV-2 force furin furin cleavage site Gamma human clinical trials human population hydrolysis hydropathy hydrophilic hydrophobic interaction in silico Infection Interaction interactions interface investigated Lambda molecular Molecular biology molecular dynamic simulations molecular dynamics mutant mutants mutate Mutation omicron Omicron variants pharmacophores polar Protein RBD RBD binding RBD-ACE2 receptor Receptor-binding domain referred to replacement Replication Research residue residues role S-protein salt salt bridges SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 variants SARS-CoV-2 virus sartans Spread suggested target targets tetrazole the RBD the receptor-binding domain the SARS-CoV-2 virus Therapies translation Treatment treatment of COVID-19 Trigger understanding variant variants viral infection virus wild-type virus π-π interaction [DOI] 10.3390/v14051029 PMC 바로가기 [Article Type] Article
Israeli news media coverage of COVID-19 and use of cannabis and tobacco: A case study of inconsistent risk communicationCovid-19의 이스라엘 뉴스 미디어 보도 및 대마초 및 담배 사용 : 일관성없는 위험 커뮤니케이션의 사례 연구Article Published on 2022-05-012022-08-31 Journal: The International Journal on Drug Policy [Category] MERS, 치료제, [키워드] Analysis article association Behavior cannabis circulation content Content analyses Coverage COVID-19 COVID-19 infection disease severity Effect highest Inconclusive increased risk Infection information less majority mass Mass media media medical cannabis New news media positive Quantitative Recreational cannabis reduced referred to reported Research risk Risk communication risk of COVID-19 significantly more Substance use Tobacco Topic while [DOI] 10.1016/j.drugpo.2022.103648 PMC 바로가기 [Article Type] Article