Heart up! RCT protocol to increase physical activity in cardiac patients who report hopelessness: Amended for the COVID-19 pandemic마음을 위로! 절망감을 호소하는 심장병 환자의 신체 활동을 증가시키는 RCT 프로토콜: COVID-19 범유행을 위해 수정됨Article Published on 2021-04-012022-09-11 Journal: Research in nursing & health [Category] 임상, [키워드] adverse event adverse events aims cardiac Cardiac rehabilitation Care contribute COVID-19 COVID-19 pandemic death determine Effect Effectiveness enrolled finding Health heart heart disease hopelessness IHD Intervention investigated ischemic heart disease maintain moderate Nurse outcomes participant Patient per day physical physical activity promote protocol Randomized Randomized controlled trial Rate RCT rehabilitation Research Research protocol research protocol. researcher Self-management Significant other Social support SOS Support three groups while [DOI] 10.1002/nur.22106 PMC 바로가기 [Article Type] Article
A systematic review and meta-analysis protocol examining the clinical characteristics and epidemiological features of olfactory dysfunction (OD) in coronavirus disease 2019 (COVID-19)Protocol Published on 2021-03-112022-10-28 Journal: Systematic Reviews [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Analysis Anosmia article caused China Chinese CINAHL Clinical characteristics Clinical data clinical evidence Clinical outcome clinical presentation CNKI Comprehensive conducted coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 patients database demographics described disease dysfunction epidemiological exclusion criteria feature human population identify IMPROVE include Inclusion Infrastructure item knowledge Meta-analysis olfactory olfactory dysfunction outbreak outcome pandemic Patient peer-reviewed performed plethora Prospective protocol Registered Reporting Research Research protocol review robust SARS-CoV-2 screened screening process searched Smell loss statistical analysis supplementary material systematic review VIP [DOI] 10.1186/s13643-021-01624-6 PMC 바로가기 [Article Type] Protocol
Pride and Prejudice during the COVID-19 Pandemic: The Misfortune of Inappropriate Clinical Trial DesignCOVID-19 전염병 동안의 오만과 편견: 부적절한 임상 시험 설계의 불행Article Published on 2021-03-012022-09-11 Journal: Journal of Epidemiology and Global Health [Category] SARS, 임상, [키워드] anticipated antivirals classic clinical Clinical outcome clinical trial clinical trials collaboration complications conducted controlled trials coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Effectiveness Emergency evaluate example global pandemic Health Organization Intervention management MOST multi-center non-randomized studies non-randomized study pandemic Placebo Placebo effect practicality precedence Pride and Prejudice primary endpoint randomization Randomized controlled trials randomized trials Registered Research protocol secure several limitation several limitations Simultaneous single-arm single-arm. single-center therapeutic Treatment Trial World Health Organization [DOI] 10.2991/jegh.k.200729.001 PMC 바로가기 [Article Type] Article
The Large Action of Chlorpromazine: Translational and Transdisciplinary Considerations in the Face of COVID-19Pharmacology Published on 2020-12-162022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Action activity acute respiratory syndrome addition anti-SARS-CoV-2 activities Antipsychotics Antiviral antiviral activity antiviral medication antiviral properties Care caused Cell cell entry chlorpromazine clathrin Clathrin-mediated endocytosis clinical trial clinical trials coronavirus Coronavirus disease 2019 Course COVID-19 COVID-19 patient CPZ Critical defined described dosage drug early stage Efficacy evaluated event face good quality Health Human Infection information Interaction Largactil maintain mechanism of action medication Neuropsychiatric pandemic phenothiazine professional provided psychiatrist psychiatry psychotropic drug regimen Research protocol SARS-CoV-2 second wave Side effects Spread treat Treatment viral entry virus [DOI] 10.3389/fphar.2020.577678 PMC 바로가기 [Article Type] Pharmacology
The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 OutbreakMedicine Published on 2020-09-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Affect Antiviral antivirals clinical clinical trials clinicians and researcher compassionate use condition coronavirus disease COVID-19 COVID-19 pandemic database described disease Drug development effective Efficacy effort Emergency Epidemiology European feature Healthcare system identify immunomodulators investigated management nine off-label outbreak pandemic pharmacological intervention phase Phase 3 profile provide Research Research protocol research protocols SARS-CoV-2 SARS-COV-2 infection significant effect supportive care syndrome Testing therapeutic Therapeutics Treatment union vaccination with COVID-19 [DOI] 10.3389/fmed.2020.552991 PMC 바로가기 [Article Type] Medicine
The burden, admission, and outcomes of COVID-19 among asthmatic patients in Africa: protocol for a systematic review and meta-analysisResearch Published on 2020-09-042022-10-28 Journal: Asthma Research and Practice [Category] COVID-19, [키워드] Admission Africa applied Asthma asthmatic asthmatic patient Asthmatic patients burden Care carried Characteristics Clinical practice Cochrane Library Control coronavirus disease Coronavirus disease 2019 COVID COVID-19 data extraction database deaths distribution Egger’s test European Evidence Health HINARI improvement independent item Meta-analysis observational study outbreak outcome Patient prevention professional Prospective protocol random-effect Registered reported Reporting Research protocol risk of bia systematic review variable Web of Science World Health Organization Wuhan, China [DOI] 10.1186/s40733-020-00061-x PMC 바로가기 [Article Type] Research
Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19) A research protocol3900 Published on 2020-08-212022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] addition Adult patient build caused Clinical deterioration cohort study contagious Coronavirus disease 2019 COVID-19 COVID-19 patients Critical Critical care Critically ill Critically ill patient detect deteriorate Deterioration determine development diagnosed with COVID-19 disease disease severity driven by early warning example excluded hospital Hypothesis ICU immunosuppression state implementation include increase increased risk Intensive intensive care interval Intervention lactating medical resource mortality rate Novel coronavirus Nurses outcome Patient patient self-reporting patients Physicians Pneumonia pregnant Primary outcome problems proportion prospective cohort study provide public health rapid response recommendations recruited required Research Research protocol risk secondary significantly transfer Treatment Vaccine [DOI] 10.1097/MD.0000000000021874 PMC 바로가기 [Article Type] 3900
Effectiveness of extracorporeal blood purification (hemoadsorption) in patients with severe coronavirus disease 2019 (COVID-19)중증 코로나바이러스감염증-19(COVID-19) 환자의 체외 혈액 정화(혈액흡착) 효과Research Article Published on 2020-08-202022-08-13 Journal: BMC Nephrology [Category] MERS, 임상, [키워드] age Antiviral blindness Blood purification C-reactive protein changed clinical clinical trials conducted Continuous renal replacement therapy continuous venovenous hemofiltration Controlled trial coronavirus coronavirus disease Coronavirus infection COVID-19 COVID-19 patient COVID-19 patients Critical illness Critically ill critically ill COVID-19 patients Cytokines drugs Efficacy Elimination enrolled evaluate extracorporeal blood purification Extracorporeal dialysis Extracorporeal hemoadsorption FIVE general condition hemoadsorption Hemoperfusion IL-6 IMPROVE Inflammatory cytokines Intervention Iran IRCT20150704023055N2 large prospective multicenter trials Mean SpO2 Medical Sciences men mode Multicenter trial oxygen oxygen saturation participant Patient peripheral Peripheral capillary oxygen saturation positive clinical improvement Protein randomization randomization and blindness recruited reduction reference number Registered registry renal replacement therapy replacement therapy Research protocol respiratory Result selected Serum IL-6 severe coronavirus disease SpO2 state hospital Therapeutic approach therapeutic approaches Treatment Trial registration university website women [DOI] 10.1186/s12882-020-02020-3 PMC 바로가기 [Article Type] Research Article
The Strategic Alliance between Clinical and Molecular Science in the War against SARS-CoV-2, with the Rapid-Diagnostics Test as an Indispensable Weapon for Front Line DoctorsProtocol Published on 2020-06-222022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] Accuracy Alliance antibody clinical colloidal gold rapid test detect Diagnosis diagnostic diagnostics doctor Efficacy epidemiological evaluate IgM and IgG immunoassay immunochromatographic immunochromatographic rapid test imperative LINE methodology outbreak point-of-care Rapid test Research protocol SARS- CoV-2 SARS-CoV-2 Science sensitivity Serological assay serological assays specificity Spread Test weapon [DOI] 10.3390/ijms21124446 PMC 바로가기 [Article Type] Protocol