Covariance predicts conserved protein residue interactions important for the emergence and continued evolution of SARS-CoV-2 as a human pathogen공분산은 인간 병원체로서 SARS-CoV-2의 출현과 지속적인 진화에 중요한 보존된 단백질 잔기 상호작용을 예측합니다Article Published on 2022-07-272022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] allele alleles Amino acid amino acid residue amino acid residues Analysis approach caused change Combination comprehensive analysis conserved coronavirus CoV CoV genome covariance CoVs difference dominant Epidemics Evolution Evolution of SARS-CoV-2 exhibited followed by Frequency Genome host adaptation human pathogen implicated incrementally independent Interaction Lineage lineages nucleotide occurred Pandemics Pathogens predict Protein protein sequence Region reservoirs residue SARS-CoV-2 SARS-CoV-2 variants statistically unique Viral protein Viral proteins β-coronavirus β-Coronaviruses [DOI] 10.1371/journal.pone.0270276 PMC 바로가기 [Article Type] Article
Targeting TFH cells in human diseases and vaccination: rationale and practice Reviews Published on 2022-07-112022-10-05 Journal: Nature Immunology [Category] 바이오마커, 유전자 메커니즘, [키워드] allergens antibody antibody affinity Antigen approach Autoantigens B cell B cells boost CD4+ T cell Cell cytokine disease disease pathogenesis Efficacy facilitate human disease Humoral immunity Infection knowledge lymphomagenesis maturation mechanisms memory pathogen clearance pathogenic protective antibody response receptor regulate Regulation reservoirs response Support survival T cell targeting TCR therapy Vaccine [DOI] 10.1038/s41590-022-01253-8 [Article Type] Reviews
The concept of one health applied to the problem of zoonotic diseasesReview Published on 2022-07-012023-06-22 Journal: Reviews in Medical Virology [Category] 조류인플루엔자, [키워드] Diseases One Health concept reservoirs viral zoonoses [DOI] 10.1002/rmv.2326 [Article Type] Review
Discovery of a Novel Coronavirus in Swedish Bank Voles ( Myodes glareolus)스웨덴 은행 들쥐(Myodes glareolus)에서 신종 코로나바이러스 발견Article Published on 2022-06-012022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Bank bank voles bat bats Betacoronavirus caused circulating coronavirus COVID-19 disease Europe Health interface Lineage mammalian novel novel Betacoronavirus occur pandemic phylogenetic analyses Phylogenetic analysis Prevalence reservoirs RNA-sequencing rodents SARS-CoV-2 severe acute respiratory syndrome Coronavirus Surveillance Swedish virus vole [DOI] 10.3390/v14061205 PMC 바로가기 [Article Type] Article
Can periodontal pockets and caries lesions act as reservoirs for coronavirus?치주낭과 충치 병변이 코로나바이러스의 저장소 역할을 할 수 있습니까?Article Published on 2022-04-012022-09-11 Journal: Molecular oral microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplify approach Asymptomatic Can caries Chain Reaction coronavirus cross-sectional cross-sectional study Ct value detect dissemination evaluate Genes infections information knowledge lesion lesions negative control participant Patient patients periodontal pocket polymerase chain polymerase chain reaction positive positive control positive COVID-19 real-time polymerase chain reaction reservoir reservoirs RT-PCR S gene SARS-CoV-2 SARS-CoV-2 detection sensitivity severe acute respiratory syndrome Coronavirus specificity symptomatic the mean the SARS-CoV-2 virus while [DOI] 10.1111/omi.12362 PMC 바로가기 [Article Type] Article
Alphacoronavirus in a Daubenton’s Myotis Bat ( Myotis daubentonii) in Sweden스웨덴의 Daubenton's Myotis 박쥐( Myotis daubentonii)의 알파 코로나바이러스Article Published on 2022-03-082022-09-11 Journal: Viruses [Category] 치료기술, 치료제, [키워드] alphacoronavirus Analysis bat bats Complete coronavirus CoV COVID-19 pandemic CoVs Europe feces female Finnish involved Myotis Myotis daubentonii Next-generation sequencing Phylogenetic analysis Pipistrellus Pipistrellus pygmaeus processed protocol public health required reservoir reservoirs Saliva sequenced species stimulated Strains summer Surveillance Sweden tested Transmission virus virus genome [DOI] 10.3390/v14030556 PMC 바로가기 [Article Type] Article
Impact of SARS-CoV-2 Alpha variant (B.1.1.7) on prisons, EnglandSARS-CoV-2 알파 변종(B.1.1.7)이 영국 교도소에 미치는 영향Article Published on 2022-03-012022-09-11 Journal: Public health [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alpha Alpha variant attack rate B.1.1.7 COG-UK coronavirus COVID-19 COVID-19 case COVID-19 infection COVID-19 outbreak England FIVE genomic information hospitalisation hospitalisations Impact Infectious disease infectious disease outbreak interquartile range IQR Laboratory likelihood outbreak Outbreaks prison prisons required reservoir reservoirs SARS-CoV-2 second wave Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 the median vaccination variant variants variants of concern whole-genome sequencing [DOI] 10.1016/j.puhe.2021.12.018 PMC 바로가기 [Article Type] Article
SARS‐CoV‐2 Omicron variant: A next phase of the COVID‐19 pandemic and a call to arms for system sciences and precision medicinePerspective Published on 2022-02-112022-10-30 Journal: MedComm [Category] COVID-19, [키워드] 3D models Arm artificial B.1.1.529 continuous variation coronavirus disease correlated COVID‐19 COVID‐19 infection Defense delta variant diagnose diagnostics Efficiency exhibited Health health systems high mortality Hospitalization in vitro Infection intelligence introduced mechanism mutated Mutation mutations nanomedicine natural immunity omicron pandemic Pathogenesis Perspective Precision precision medicine provided receptor‐binding domain recommendation reservoirs Respiratory Coronavirus SARS‐CoV‐2 SARS‐CoV‐2 mutations severity Spread Structure subtype System the spike protein Vaccines variant variants viral infection virus VOCs World Health Organization [DOI] 10.1002/mco2.119 PMC 바로가기 [Article Type] Perspective
An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde traffickingSARS-CoV-2 스파이크의 확장된 모티프는 역행 인신매매에서 숙주 코토머의 결합 및 방출을 조절합니다Article Published on 2022-02-082022-09-10 Journal: Communications Biology [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] bats binding Binding assays Biophysical methods canonical complex conserved COPI Critical Crystallography cytosolic determinant dibasic ERGIC Host humans identify implication in silico analysis interact modulate motif Mutagenesis pangolins progeny Protein structure predictions proteome released reservoirs residue SARS-CoV-2 selectivity sequence Spike protein Spike proteins subunit the SARS-CoV-2 Viral X-ray crystallography zoonotic β-coronavirus β-Coronaviruses [DOI] 10.1038/s42003-022-03063-y PMC 바로가기 [Article Type] Article
Pathological sequelae of long-haul COVID장거리 코로나의 병적 후유증Review Published on 2022-02-012022-09-11 Journal: Nature Immunology [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] Autoimmunity clinical Concentration convalescent individuals coronavirus disease Coronavirus disease 2019 COVID COVID-19 diagnostic Diagnostic strategies disorder Dyspnea fatigue heterogeneous include increasingly Inflammation involved malaise Manifestations memory Neuropsychiatric organ system organ-specific pathological pathophysiological mechanism present reservoirs review successive wave successive waves syndrome variety Viral variants [DOI] 10.1038/s41590-021-01104-y PMC 바로가기 [Article Type] Review