Histopathological Evaluation of Deceased Persons in Lusaka, Zambia With or Without Coronavirus Disease 2019 (COVID-19) Infection: Results Obtained From Minimally Invasive Tissue Sampling코로나바이러스 감염증 2019(COVID-19) 감염 여부에 관계없이 잠비아 루사카에서 사망한 사람의 조직병리학적 평가: 최소 침습적 조직 샘플링에서 얻은 결과Supplement Articles Published on 2021-12-152022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] 48 hour 48 hours abnormality Acute kidney injury age AIDS alveolar damage Analysis Autopsy Chain Reaction collected Community coronavirus disease Coronavirus disease 2019 country COVID-19 cycle threshold death Deceased diabete diabetes Diagnosis died diffuse Diffuse alveolar damage eligible enrolled hepatic steatosis Human Human immunodeficiency virus immunodeficiency virus individual individuals infections information interstitial invasive kidney kidneys limitation liver lung lung abnormalities male median age minimally invasive tissue sampling Morgue MOST Nasopharyngeal swab nasopharyngeal swab specimen nonspecific occurred offer open pathologic pathological change pathological changes pathology pathophysiology Patient PCR performed Person pneumonias polymerase chain polymerase chain reaction Postmortem prevalent pulmonary Quantitative respiratory Result reverse transcriptase reverse transcriptase PCR Sample sampling subject Surveillance syndrome Teaching threshold thrombi tissue tissue biopsy Tuberculosis university Vascular Viral Viral pneumonia viral pneumonias [DOI] 10.1093/cid/ciab858 PMC 바로가기 [Article Type] Supplement Articles
Development of a rapid viability RT-PCR (RV-RT-PCR) method to detect infectious SARS-CoV-2 from swabs면봉에서 감염성 SARS-CoV-2를 검출하는 신속한 생존력 RT-PCR(RV-RT-PCR) 방법 개발Article Published on 2021-11-012022-09-11 Journal: Journal of virological methods [Category] SARS, 치료기술, [키워드] 96-well plate acute respiratory syndrome coronavirus Algorithm Analysis antiviral drug COVID-19 COVID-19 pandemic Culture cycle threshold detect determine development enrichment epidemiological include increase in Incubation period Infectious SARS-CoV-2 Infectious virus PCR method Post-infection potential surface Rapid Rapid viability representing required respiratory resulting reverse transcriptase reverse transcriptase PCR RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virion SARS-CoV-2 virions Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Spread Swab swab sample swab samples swabs Transmission Ultrafiltration viability Viral detection viral infection virions virus [DOI] 10.1016/j.jviromet.2021.114251 PMC 바로가기 [Article Type] Article
Diagnostic Efficacy and Tolerability of Molded Plastic Nasopharyngeal Swab (FinSwab) Compared to Flocked Nylon Swab in Detection of SARS-CoV-2 and Other Respiratory VirusesSARS-CoV-2 및 기타 호흡기 바이러스의 검출에서 플록 나일론 면봉과 비교한 성형 플라스틱 비인두 면봉(FinSwab)의 진단 효능 및 내약성Comparative Study Published on 2021-10-202022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, [키워드] age analyzed assays clinical setting collected comparable Copan coronavirus COVID-19 COVID-19 infection cycle threshold detection deviation diagnostic diagnostics discomfort Efficacy equipment evaluate Italy mRNA nasopharyngeal nasopharyngeal sample nasopharyngeal sampling Nasopharyngeal swab nasopharyngeal swabs no difference nostril Nylon OC43 Other Other respiratory viruses Patient patients plastic plastic injection molding positive Randomized respiratory respiratory virus respiratory viruses reverse transcriptase reverse transcriptase PCR rhinovirus RT-PCR sampling SARS-CoV-2 Spread subset supply Swab swabs symptomatic Tolerability virus β-actin [DOI] 10.1128/Spectrum.00736-21 PMC 바로가기 [Article Type] Comparative Study
Shared Mutations in Emerging SARS-CoV-2 Circulating Variants May Lead to Reverse Transcription-PCR (RT-PCR)-Based Misidentification of B.1.351 and P.1 Variants of Concern신종 SARS-CoV-2 순환 변이체의 공유 돌연변이로 인해 우려되는 B.1.351 및 P.1 변이체의 역전사-PCR(RT-PCR) 기반 오식으로 이어질 수 있음Observation Published on 2021-10-132022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, [키워드] B.1.351 Candidates concern COVID-19 E484K evaluated identify misidentification Mutation mutations N501Y P.1 PCRs reverse transcriptase PCR RT-PCR RT-PCRs SARS-CoV-2 SARS-CoV-2 variant Sequencing variants VoC WGS whole-genome sequencing [DOI] 10.1128/Spectrum.00816-21 PMC 바로가기 [Article Type] Observation
Genomic Characterization of Diverse Bat Coronavirus HKU10 in Hipposideros BatsArticle Published on 2021-09-292022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Accessory genes addition Alpha alphacoronavirus Aselliscus bat bat coronavirus bat coronavirus HKU10 bats betacoronaviruses Cell cell tropism characterization China circulating collected Continuous coronavirus Coronaviruses correlated defined demonstrated distribution Evolution expand fecal samples full-length genome Genes genetic diversity Genotype Guangxi Hainan Hipposidero interspecies transmission investigated lentivirus lineages much higher New novel lineage Phylogenetic analysis polyproteins positive reported reservoir reverse transcriptase PCR Rousettus screened selective sequenced spike gene strain variant variety virus zoonotic disease [DOI] 10.3390/v13101962 PMC 바로가기 [Article Type] Article
A Simple Reverse Transcriptase PCR Melting-Temperature Assay To Rapidly Screen for Widely Circulating SARS-CoV-2 Variants광범위하게 순환하는 SARS-CoV-2 변이체를 신속하게 스크리닝하기 위한 간단한 역전사효소 PCR 용융 온도 분석Article Published on 2021-09-202022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 변종, 치료기술, [키워드] Alpha amplify assays B.1.1.7 B.1.351 B.1.351 variant Brazil can be used characteristic clinical samples cultured virus detect E484K E484K mutation Epsilon Genome sequencing genomic gold gold standard identify India limit of detection melting melting temperature molecular Mutation N501Y Patient PCR primer probe public health reverse transcriptase reverse transcriptase PCR RNA RT-PCR Sanger sequencing SARS-CoV-2 SARS-CoV-2 variants Screen screening test simple sloppy molecular beacon South Africa Spread Strains Surveillance temperature the SARS-CoV-2 the United State time-consuming transmission of SARS-CoV-2 United Kingdom United States USA variant variants variants of concern VoC VOCs WA1/2020 was performed wild type wild-type [DOI] 10.1128/JCM.00845-21 PMC 바로가기 [Article Type] Article
Clinical progression of patients with COVID-19 in Lagos State, NigeriaResearch Published on 2021-09-042022-10-29 Journal: Translational Medicine Communications [Category] COVID-19, [키워드] adhere Admission age antiviral medicine average Care clearance clinical clinical progression confidential interval confirmed COVID-19 case cough COVID-19 COVID-19 patients COVID-19 research Deterioration Dexamethasone duration of fever enrolled Epidemiology female ICU ICU patient Infection intensive care unit Lago Lagos majority male median Mortality NCDC Nigeria non-ICU patient occurred onset of symptoms Patient patients patients with COVID-19 progression radiological radiological improvement reduce Result reverse transcriptase PCR risk SARS-CoV-2 spread of COVID-19 state supplementary oxygen Support Symptom Symptomatic patients test negative the median Treatment upper respiratory tract virus were given [DOI] 10.1186/s41231-021-00099-w PMC 바로가기 [Article Type] Research
Saliva for molecular detection of SARS-CoV-2 in school-age children학령기 아동의 SARS-CoV-2 분자 검출용 타액Observational Study Published on 2021-09-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age carried children Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cycle cycle threshold demonstrated determine diagnostic Diagnostic accuracy Dubai Gender Kappa coefficient male molecular nasopharyngeal Nasopharyngeal swab Negative predictive value not differ NP swab participant positive predictive values presenting provided RdRP RdRp gene recruited reported respiratory reverse transcriptase reverse transcriptase PCR RT-PCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 RT-PCR significantly higher specificity specimen Standard deviation Swab tested threshold United Arab Emirates virus detection [DOI] 10.1016/j.cmi.2021.02.009 PMC 바로가기 [Article Type] Observational Study
Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2중증 급성 호흡기 증후군 코로나바이러스 2에 의한 기간 태반 감염에 대한 임상 및 시험관 내 증거Clinical Trial Published on 2021-09-012022-09-11 Journal: The American journal of pathology [Category] SARS, 유전자 메커니즘, 임상, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Cell clinical consequence coronavirus coronavirus 2 coronavirus disease Defense demise during pregnancy enzyme expression fetus Host immunohistochemistry In situ hybridization Infection mechanism membrane mother Newborn not express Placenta Placental infection Placentas positive control Pregnancy Pregnancy confirmed protease Protein quantification question raise receptor Replication respiratory reverse transcriptase reverse transcriptase PCR SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 virions Serine serine 2 severe acute respiratory syndrome Coronavirus supernatant syncytium term TMPRSS2 transmembrane transmembrane protease serine 2 Transmission undetectable Vero E6 vertical transmission virus [DOI] 10.1016/j.ajpath.2021.05.009 PMC 바로가기 [Article Type] Clinical Trial
Molecular Mirror Technology Facilitates High-Throughput, Accurate SARS-CoV-2 TestingMolecular Mirror 기술은 높은 처리량의 정확한 SARS-CoV-2 테스트를 용이하게 합니다.Research Article Published on 2021-08-252022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI acute SARS-CoV-2 infection analyzed Antigen approved Automation benefit can be used center Characteristics comparable confidence interval country COVID-19 COVID-19 pandemic Critical detect determine diagnose diagnostic diagnostic testing diagnostics Efficacy Emergency use authorization EUA evaluated extraction extraction-free method identify individual landscape limitation Mirror Molecular Mirror nasal NMR nuclear nuclear magnetic resonance nucleic acid nucleic acid amplification nucleic acid extraction offer PCR test PCR tests PCR-based assays positive proof proof of concept protocol Rapid Rapid tests reverse transcriptase reverse transcriptase PCR RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleic acid SARS-CoV-2 testing sensitivity specimen subject Supply chain supply chains TaqPath technology Test Testing virus detection [DOI] 10.1128/Spectrum.00392-21 PMC 바로가기 [Article Type] Research Article