CRISPR-cas13 enzymology rapidly detects SARS-CoV-2 fragments in a clinical settingCRISPR-cas13 효소는 임상 환경에서 SARS-CoV-2 단편을 빠르게 감지합니다.Article Published on 2021-12-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 변종, 치료기술, 치료제, [키워드] 95% CI Accuracy approach Cas13 enzymology Clinical diagnosis clinical samples clinical setting conserved consumables controls COVID-19 COVID-19 patient CRISPR CRISPR technology CRISPR-Ca detect diagnosed diagnostics EUA evaluate evaluated expected Fluorescence Fluorescence readout form Genome highlight Increased Infectious disease isolates N gene nucleic acid Nucleic acid detection nucleic acids ORF1 ORF1ab gene positive protocol RNase P RT-LAMP RT-PCR assay RT-PCR assays SARS-CoV-2 selected Specific target thresholds triggered Vaccine variant viral loads [DOI] 10.1016/j.jcv.2021.105019 PMC 바로가기 [Article Type] Article
Comparison of COVID-19 mitigation and decompression strategies among homeless shelters: a prospective cohort study노숙자 보호소의 COVID-19 완화 및 감압 전략 비교: 전향적 코호트 연구Article Published on 2021-12-012022-09-11 Journal: Annals of epidemiology [Category] SARS, 치료기술, [키워드] 95% CI adopted age assays Community intervention conducted COVID-19 COVID-19 mitigation COVID-19 symptom Daily Daily temperature Effectiveness Follow-up Gender Health disparities higher odd higher odds highlight Homeless population hotel Infection Massachusett Massachusetts Mitigation Mitigation strategies. Odds ratio Odds ratios outcome pandemic Parking lot PCR assays performed positive Prevent prospective cohort study rising RT-PCR assays SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 transmission Support Symptom temperature [DOI] 10.1016/j.annepidem.2021.08.023 PMC 바로가기 [Article Type] Article
CAN IgG ANTIBODIES DIRECTED AGAINST DIFFERENT TARGETS SOLVE THE PROBLEM OF FALSE-POSITIVE RESULTS IN SARS-CoV-2 SEROLOGY?다른 표적에 대한 IgG 항체가 SARS-CoV-2 혈청학에서 위양성 결과의 문제를 해결할 수 있습니까?Article Published on 2021-12-012022-09-12 Journal: Acta clinica Croatica [Category] SARS, 진단, [키워드] addition Anti- SARS-CoV-2 IgG antigens cross-reactivity ELFA ELISA False-positive results France global pandemic IgG Infection Italy medium observation offer other coronavirus Patient positive Positive predictive value positive result RT-PCR assays SARS-CoV SARS-CoV 2 SARS-CoV-2 SARS-COV-2 infection serologic test serologic tests serology serology test serology testing Spread tested [DOI] 10.20471/acc.2021.60.04.25 PMC 바로가기 [Article Type] Article
Clinical evaluation of SARS-CoV-2 antigen-based rapid diagnostic test kit for detection of COVID-19 cases in BangladeshResearch article Published on 2021-11-222022-10-05 Journal: Heliyon [Category] 변종, 진단, 치료기술, [키워드] acute respiratory syndrome age Bangladesh clinical clinical evaluation clinically conducted coronavirus Coronavirus disease 2019 COVID-19 COVID-19 case detectable diagnosed diagnostic disease onset evaluate FIVE indicated Infection management MOST Negative predictive value NPV pandemic positive Positive predictive value PPV rapid antigen test Rapid diagnostic test RDT real-time RT-PCR RT-PCR RT-PCR assay RT-PCR assays SARS-CoV-2 SARS-CoV-2 variants sensitivity Sensitivity and specificity Sex Standard Q suspected patients Swab Test [DOI] 10.1016/j.heliyon.2021.e08455 [Article Type] Research article
Clinical evaluation of the automated Abbott RealTi m e SARS-CoV-2, Alinity m SARS-CoV-2, and Alinity m Resp-4-Plex assaysArticle Published on 2021-10-222022-10-04 Journal: Journal of virological methods [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] Abbott Alinity m assays automated Beta clinical clinical samples cross-reactivity detection infected with SARS-CoV-2 influenza A influenza B multiplex objective positive Precision RdRP Real-time PCR respiratory pathogen Result RSV RT-PCR assays SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA specimen turnaround time variants [DOI] 10.1016/j.jviromet.2021.114338 PMC 바로가기 [Article Type] Article
A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity역동적인 뮤신 mRNA 시그니처는 COVID-19 질병 표현 및 중증도와 관련이 있습니다Clinical Medicine Published on 2021-10-082022-09-10 Journal: JCI Insight [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료제, [키워드] analyzed Antwerp association AUC Baricitinib Blood Clinical outcome component correlated Course COVID-19 COVID-19 patient COVID-19 symptoms COVID-19 treatment Critical Critical case critical cases Critically ill critically ill COVID-19 patients diagnosing difference disease drug ENhance epithelial cells expression expression profile Favipiravir foundation healthy control healthy controls induce Innate immunity investigated lung tissue management Mild mild case mild cases Molecular biology Mortality mRNA mRNA expression MUC1 MUC13 MUC16 MUC2 MUC20 MUC21 MUC4 MUC6 mucin mucins Organ failure overexpression parameters Patient patients with COVID-19 patients without COVID-19 pulmonary epithelial cells Remdesivir respiratory Respiratory Support ROC RT-PCR assays SARS-COV-2 infection secondary infections Sensitivity and specificity severity suppress symptomatic symptomatic COVID-19 symptomatic patient Symptomatic patients Symptoms Tocilizumab transcriptional Treatment university with COVID-19 [DOI] 10.1172/jci.insight.151777 PMC 바로가기 [Article Type] Clinical Medicine
Mild SARS-CoV-2 Illness Is Not Associated with Reinfections and Provides Persistent Spike, Nucleocapsid, and Virus-Neutralizing Antibodies가벼운 SARS-CoV-2 질병은 재감염과 관련이 없으며 지속적인 스파이크, 뉴클레오캡시드 및 바이러스 중화 항체를 제공합니다Research Article Published on 2021-09-012022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료법, [키워드] antibodies antibody antibody assay Antibody assays Antibody Response assays clinical conducted correlated COVID-19 COVID-19 antibody COVID-19 infection COVID-19 testing decrease disease Enrollment Evidence evidence of exposure to FDA Follow-up Hospitalization illness Immunity immunoassay immunoassays immunoserology individual Infection infection rates Mild Mild disease mild infection MOST neutralization activity nucleocapsid nucleocapsid responses Participants persistence persistent produced prospective cohort study pseudoviral neutralization Reinfection risk RT-PCR RT-PCR assays SARS-CoV-2 SARS-CoV-2 RT-PCR screened Seroconversion serology seronegative seropositive subject spike study duration subject subsequent Symptoms Uncertainty vaccination Vaccine Viral viral neutralization widespread [DOI] 10.1128/Spectrum.00087-21 PMC 바로가기 [Article Type] Research Article
Molecular Diagnosis of SARS-CoV-2: Assessing and Interpreting Nucleic Acid and Antigen TestsResearch Article Published on 2021-07-192022-10-28 Journal: Pathogens and Immunity [Category] COVID-19, [키워드] accelerated acid amplification Antigen antigen-detection Assessing breadth clinical setting Clinical symptoms COVID-19 disease COVID-19 pandemic Defense diagnosing diagnostic tests disease early stage Epidemiology expression Government impacts infected individuals information Interpreting NAAT Novel coronavirus nucleic acid organization outbreak pandemic pathogen Patient care patient triage POC point-of-care Population populations PROTECT provided public health recommendation required Result risk RT-PCR assays RT-PCR testing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 variants sequence Sequencing specimen Stage Test Transmission transmission patterns Treatment strategies vaccine production [DOI] 10.20411/pai.v6i1.422 PMC 바로가기 [Article Type] Research Article
Rapid Isothermal Amplification for the Buccal Detection SARS-CoV-2 in the Context of Out-Patient COVID-19 ScreeningCommunication Published on 2021-06-162022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] applied Buccal Context COVID-19 detection Diagnosis exhibited indicated isothermal amplification less nasopharyngeal swabs performed point of care positive positive result protocol Rapid reported RT-PCR RT-PCR assay RT-PCR assays Saliva SARS-CoV-2 SARS-CoV-2 RNA Screening supervision Support Swab [DOI] 10.3390/jcm10122643 PMC 바로가기 [Article Type] Communication
Resource-efficient internally controlled in-house real-time PCR detection of SARS-CoV-2SARS-COV-2의 자원 효율 내부적으로 내부 제어 사내 실시간 PCR 검출Research Published on 2021-06-022022-09-01 Journal: Virology Journal [Category] MERS, SARS, 진단, 치료기술, [키워드] addition approach assays COVID-19 COVID-19 crisis crisis management diagnostic diagnostics Genome genomic house indicate information Internal control management market nucleic acid Patient PCR PCR assay PCR assays protocol reaction reagent reagents Real-time PCR real-time RT-PCR regions Result RNA RT-PCR assays SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 RNA sequence specimen supplementary material [DOI] 10.1186/s12985-021-01559-3 PMC 바로가기 [Article Type] Research