SARS-CoV-2 immunity – Page 2 – Communicable Diseases Research

Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2

BNT162b2 백신을 접종한 노인의 21개 SARS-CoV-2 변이체에 대한 항체 활성 중화

Article

Published on 2022-08-012022-09-11
Journal: Nature Microbiology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술,

COVID-19 in the 47 countries of the WHO African region: a modelling analysis of past trends and future patterns

WHO 아프리카 지역 47개국의 COVID-19: 과거 동향 및 미래 패턴의 모델링 분석

Article

Published on 2022-08-012022-09-11
Journal: The Lancet. Global health [Category] COVID19(2023년), SARS, 변종,

[키워드] 95% CI affected African Analysis approach build Comorbidities country Coverage COVID-19 COVID-19 infection COVID-19 infections dead death deaths estimate Fourier series Fourier sery generate hospitalisations Immunity immunogenicity Infection infections information introduced Markov decision process New pandemic public health Public health interventions reduce reported robust SARS-CoV-2 immunity SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 testing sequenced severity Statistics Surveillance susceptible the WHO Transmissibility Transmission dynamics vaccination variant variants variants of concern WHO
[DOI] 10.1016/S2214-109X(22)00233-9 PMC 바로가기 [Article Type] Article

Omicron BA.1 Mutations in SARS-CoV-2 Spike Lead to Reduced T-Cell Response in Vaccinated and Convalescent Individuals

SARS-CoV-2 스파이크의 Omicron BA.1 돌연변이는 백신 접종 및 회복기 개인의 T-세포 반응 감소로 이어집니다

Article

Published on 2022-07-192022-09-11
Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] alleles BNT162b2 BNT162b2 vaccine CD4 CD4+ T-cell CD4+ T-cell epitopes cellular immunity circulating cross-reactive cross-reactivity elicited Epitopes escape facilitated help HLA HLA class II HLA class II alleles HLA motif prediction immune Immune escape immunodominant epitope immunodominant epitopes individual infect loss of memory memory monitoring motif mRNA mRNA-based Mutation mutations natural infection Neutralizing antibodies omicron Omicron BA.1 variant predict predicted preserved reactivity response SARS-CoV-2 SARS-CoV-2 immunity selected spike Spike protein spike-protein strain T cell T cells T-cell T-cell epitope T-cell epitopes T-cell Response T-cell responses the spike protein vaccination variant virus variant virus variants
[DOI] 10.3390/v14071570 PMC 바로가기 [Article Type] Article

Study authors don’t consider waning SARS-CoV-2 immunity after vaccination in their model

연구 저자는 그들의 모델에서 백신 접종 후 SARS-CoV-2 면역 약화를 고려하지 않습니다.

Comment

Published on 2022-06-202022-09-12
Journal: CMAJ : Canadian Medical Association journal = jour [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] SARS-CoV-2 immunity vaccination
[DOI] 10.1503/cmaj.127321-l PMC 바로가기 [Article Type] Comment

Immunogenic epitope panel for accurate detection of non-cross-reactive T cell response to SARS-CoV-2

SARS-CoV-2에 대한 비교차 반응성 T 세포 반응의 정확한 검출을 위한 면역원성 에피토프 패널

Article

Published on 2022-05-092022-09-11
Journal: JCI Insight [Category] COVID19(2023년), SARS, 치료기술,

[키워드] absence Accuracy Antigen antigens association Asymptomatic clinical clinical trial clinical trials Cohort collected Combination Complete contributing to convalescent COVID-19 COVID-19 pandemic cross-reactive described diagnostic Diagnostic accuracy diagnostic specificity donors effective epitope Epitopes exclusion full-length healthy HLA HLA allele Immune cell immune cells immunodominant immunogenic immunogenicity in vitro independent individual individuals offered peptides PROTECT reactivity robust SARS-CoV-2 SARS-CoV-2 immunity sensitivity seronegative specificity T cell T cell response T cells
[DOI] 10.1172/jci.insight.157699 PMC 바로가기 [Article Type] Article

Quantitative serology for SARS-CoV-2 using self-collected saliva and finger-stick blood

자가 채취한 타액과 손가락 채혈을 이용한 SARS-CoV-2의 정량적 혈청학

Article

Published on 2022-04-212022-09-12
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단,

Predictors of impaired SARS-CoV-2 immunity in healthcare workers after vaccination with BNT162b2

BNT162b2 백신 접종 후 의료 종사자의 SARS-CoV-2 면역 장애 예측자

Article

Published on 2022-04-142022-09-11
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, 치료기술,

[키워드] antibody Antibody titers BNT162b2 CD4 CD8 Cellular immune response cellular immune responses cellular immunity comparable Concentration convalescent detectable did not produce effective frequencies Frequency healthcare healthcare worker Healthcare workers hospital humoral humoral immune response IgG immune response immune responses Immunosuppression increased risk individual infection with SARS-CoV-2 median organ pandemic post vaccination PROTECT recipients reduced required Responder risk factor Risk factors SARS-CoV-2 SARS-CoV-2 immunity seroconversion rate significantly higher solid organ spike IgG Standard of care subject T cell T cell response T cell responses vaccination Vaccine was measured yielding
[DOI] 10.1038/s41598-022-10307-8 PMC 바로가기 [Article Type] Article

A third dose of mRNA-1273 vaccine improves SARS-CoV-2 immunity in HCT recipients with low antibody response after 2 doses

mRNA-1273 백신의 3차 접종은 2차 접종 후 항체 반응이 낮은 HCT 수혜자의 SARS-CoV-2 면역을 개선합니다

Article

Published on 2022-04-122022-09-12
Journal: Blood advances [Category] COVID19(2023년), SARS, 진단,

[키워드] Antibody Response dose HCT IMPROVE mRNA-1273 vaccine recipient SARS-CoV-2 immunity
[DOI] 10.1182/bloodadvances.2021006599 PMC 바로가기 [Article Type] Article

Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine

경구 랍도바이러스 백신을 사용한 비인간 영장류의 SARS-CoV-2 면역 강화

Article

Published on 2022-04-012022-09-12
Journal: Vaccine [Category] COVID19(2023년), SARS, 비임상, 진단,

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity

특정 체액 면역이 없는 1차 항체 결핍 환자의 중증 및 치명적인 COVID-19에서 SARS-CoV-2 T 세포 반응

Article

Published on 2022-03-102022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료법,

[키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Analysis analyzed antibody autoantibodies autoantibody Blood CD169 CD4 cellular characterized clearance clinical disease Comorbidities Comorbidity convalescent convalescent plasma Convalescent plasma (CP) coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 cytokine deficiency detectable elevated examined excluded expression fatal COVID-19 flow cytometry healthy individuals heterogeneous humoral humoral immune response IgG Immunity immunodeficiency immunological immunological mechanism Inborn errors indicate innate immune response Innate immunity interferon interferons lack marker median monoclonal antibody Monocytes morbidity Mortality mucosal naïve nucleocapsid outcome Patient patients peptide peptide pool Peripheral blood persistence phenotype primary antibody primary antibody deficiency (PAD) Primary immunodeficiencies primary immunodeficiencies (PID) producing Prophylactic respiratory response Risk factors robust SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 RNA SARS-CoV-2 spike SARS-CoV-2 viral shedding seronegative severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Severe case severe cases severe COVID-19 patient SIGLEC1 Specific T cell T cell response T cells Treatment type I interferon type I interferon response type I interferons undetectable Viral viral clearance viral shedding with COVID-19
[DOI] 10.3389/fimmu.2022.840126 PMC 바로가기 [Article Type] Article