Incubation Period of COVID-19 Caused by Unique SARS-CoV-2 Strains: A Systematic Review and Meta-analysisArticle Published on 2022-08-012022-11-16 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI Alpha variant average Beta caused conducted COVID-19 COVID-19 pandemic defined Delta delta variant described eligible facilitate identifying Incubation Incubation period infected children Infection information Isolation item key factor mean incubation period Meta-analysis mutated older patient omicron original outcome parameters Patient patients Period producing random-effect ranged reported Reporting review SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant searched Symptoms Transmission variant virulence [DOI] 10.1001/jamanetworkopen.2022.28008 PMC 바로가기
Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infectionOmicron BA.1 돌발성 감염 후 기존 교차 반응성 B 세포 기억 회상Article Published on 2022-07-292022-09-11 Journal: Science Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody Response B cell B cell memory B cell response Breakthrough infection characterized conserved coronavirus cross-reactive Donor donors facilitate feature Heterologous immune response immune responses immunodominance Infection memory B cells Messenger RNA Neutralizing antibodies neutralizing antibody omicron Preexisting immunity proportion RBD Receptor binding domain Recognition respiratory S2 subunit SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 variants sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shift understanding Vaccines VOCs [DOI] 10.1126/sciimmunol.abq3511 PMC 바로가기 [Article Type] Article
Real-life data on monoclonal antibodies and antiviral drugs in Italian inborn errors of immunity patients during COVID-19 pandemic코로나19 팬데믹 기간 동안 이탈리아 선천성 면역질환 환자의 단클론항체 및 항바이러스제 실생활 데이터Article Published on 2022-07-282022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Alpha Analysis Antiviral antiviral agent Antiviral agents antiviral drug antiviral drugs Asymptomatic Care circulating Cohort contributed Course COVID-19 COVID-19 pandemic COVID-19 severity disease disease severity duration of viral shedding Effect Efficacy error evaluated Hospital admission Hospitalization hospitalization-risk hospitalizations hospitalized patients ICU admission Immunity immunized Inborn Inborn errors inborn errors of immunity Infection Italian longitudinal lower risk mAbs mitigate monoclonal monoclonal antibodies monoclonal antibody Mortality mRNA vaccine mRNA vaccines offered Patient patients treated performed positive Prevent prophylactic measure prophylactic measures Re-infection Re-infections reduce reduced Reinfection reported respond risk Safe SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positivity SARS-CoV-2 strains SARS-CoV-2 virus severe COVID-19 severe disease Spectrum Spread Strains therapeutic therapy treated vaccination Vaccinations Viral viral shedding viral strain viral strains widespread [DOI] 10.3389/fimmu.2022.947174 PMC 바로가기 [Article Type] Article
A Comparison of Bioinformatics Pipelines for Enrichment Illumina Next Generation Sequencing Systems in Detecting SARS-CoV-2 Virus StrainsSARS-CoV-2 바이러스 균주 검출 시 Illumina 차세대 시퀀싱 시스템 강화를 위한 생물정보학 파이프라인 비교Comparative Study Published on 2022-07-262022-09-11 Journal: Genes [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Algorithm Amino acid bioinformatics bioinformatics pipeline capture method characterization coronavirus 2 coronavirus disease Coronavirus disease 2019 Coverage COVID-19 Critical Deletion downstream enrichment enrichment. full-length SARS-CoV-2 genome Generation Hope Human genome Illumina Indonesia insertion limitation Major mapped mapping metagenomic mutations next generation sequencing NGS normal nucleotide nucleotide substitution nucleotide substitutions pandemic Panel Previous studies previous study reads respiratory respiratory virus respiratory viruses SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 strain SARS-CoV-2 strains sequence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus situation SNPs strain Strains System table the SARS-CoV-2 genome utilization Variation virus worldwide pandemic worsening [DOI] 10.3390/genes13081330 PMC 바로가기 [Article Type] Comparative Study
Immune Escape Associated with RBD Omicron Mutations and SARS-CoV-2 Evolution DynamicsRBD 오미크론 돌연변이 및 SARS-CoV-2 진화 역학과 관련된 면역 탈출Review Published on 2022-07-222022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] absence Affect appearance bioinformatics COVID-19 COVID-19 pandemic described Dynamics escape Evolution explained Features Genome high affinity high mutation rate Host immune Immune escape Lineage Mutation mutation rate natural immunity omicron pathogenicity Protein RBD RBD mutations receptor SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 strains serotype Spike protein the Spike therapeutic therapeutic agent therapeutic agents Transmissibility Vaccine Vaccine development variant virus [DOI] 10.3390/v14081603 PMC 바로가기 [Article Type] Review
Phylogenetic analysis and comparative genomics of SARS-CoV-2 from survivor and non-survivor COVID-19 patients in Cordoba, Argentina아르헨티나 코르도바에서 생존자와 비생존자 COVID-19 환자의 SARS-CoV-2 계통발생 분석 및 비교 유전체학Article Published on 2022-07-142022-09-11 Journal: BMC Genomics [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis association B.1 both groups carried Clinical characteristics Clinical outcome clinical outcomes Comorbidities Comorbidity Comparative Comparative genomics Complete Córdoba coronavirus cough COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 patient COVID-19 patients Dyspnea Epidemiological study Evolution Evolution of SARS-CoV-2 Fever First wave functional Future Genes genome sequence Genome sequences genomes Genomic analysis genomic data groups Hospitalization in both groups incidence Infectious diseases Lineage majority Molecular epidemiology Mutation nasopharyngeal specimen Next-generation sequencing nine non-survivor Non-survivors Nsp3 outcomes pandemic Patient patients performed phylodynamic Prevalence Protein repertoire Research respiratory responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 mutation SARS-CoV-2 pathogenesis SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 variants SARS-CoV-2 virus Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 South America Specific specific mutation specific mutations Spike protein Spread survivor Survivors Symptom Symptoms the SARS-CoV-2 the Spike variant Variation was performed [DOI] 10.1186/s12864-022-08756-6 PMC 바로가기 [Article Type] Article
An Updated Review on SARS-CoV-2 Infection in Animals동물의 SARS-CoV-2 감염에 대한 최신 검토Review Published on 2022-07-132022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animal animal species animals be positive caused coronavirus current death delta variant event host range Human humans immunization Infection infection with SARS-CoV-2 information involved natural infection outbreak pandemic pathogenicity positive reported review SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 testing severe acute respiratory syndrome Coronavirus strain suggested Surveillance tested Testing Transmission transmission route variants variety were infected wild animals [DOI] 10.3390/v14071527 PMC 바로가기 [Article Type] Review
Humoral and Cellular Immune Responses of COVID-19 vaccines against SARS-Cov-2 Omicron variant: a systemic reviewSARS-Cov-2 오미크론 변이체에 대한 COVID-19 백신의 체액 및 세포 면역 반응: 전신 검토Review Published on 2022-07-112022-09-11 Journal: International Journal of Biological Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed B.1.1.529 booster booster dose cellular Cellular immune response cellular immune responses center contagious coronavirus 2 country COVID-19 vaccine Critical current dominant variant dose Effectiveness elicit elicited Future Genome Health Organization Heterologous homogenous homologous or heterologous humoral Humoral and cellular immune responses humoral immune response humoral immune response, cellular immune response immune Immune escape immune responses induce molecular basis multiple mutation multiple mutations mutated Mutation Neutralizing antibody response neutralizing antibody responses omicron Omicron variant PROTECT Protective public health question regimen regimens reported respiratory response robust S-protein SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Systemic review systemically T cell T cell response the SARS-CoV-2 virus vaccination Vaccination strategy Vaccine variant VoC WHO World Health Organization [DOI] 10.7150/ijbs.73583 PMC 바로가기 [Article Type] Review
Identifying SARS-CoV-2 Variants of Concern through Saliva-Based RT-qPCR by Targeting Recurrent Mutation Sites재발 돌연변이 부위를 표적으로 하여 타액 기반 RT-qPCR을 통해 우려의 SARS-CoV-2 변이체 식별Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy antibody approach characterized clinical methods complement concern COVID-19 demonstrated diagnostic diagnostics E484K Efficacy Genetic identify identifying influence investigated L452R Mask mandates Mutation nucleotides omicron performed Population screening positive probe public health public health threat qPCR qPCR assays quarantine Real-time monitoring recommendation Recurrent RNA RT-qPCR RT-qPCR assay Saliva saliva samples SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 variants screened selective Sequencing single nucleotide Site SNP South Spread Surveillance targeting Transmissibility treatment regimens variants variants of concern VoC VOCs whole genome whole genome sequence Whole genome sequencing [DOI] 10.1128/spectrum.00797-22 PMC 바로가기 [Article Type] Article
Structural Dynamics of the SARS-CoV-2 Spike Protein: A 2-Year Retrospective Analysis of SARS-CoV-2 Variants (from Alpha to Omicron) Reveals an Early Divergence between Conserved and Variable EpitopesSARS-CoV-2 스파이크 단백질의 구조 역학: SARS-CoV-2 변이체(알파에서 오미크론까지)의 2년 후향적 분석을 통해 보존된 에피토프와 가변 에피토프 간의 초기 차이가 드러났습니다.Article Published on 2022-06-152022-09-11 Journal: Molecules [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] abrogated ACE2 binding ADE analyzed antibodies antibody Antibody-dependent enhancement antiviral strategy approaches bind binding circulating conformational change conserved COVID-19 infection D614G D614G mutation Delta determined by Divergence domain Dynamics epitope Epitopes Evolution facilitate facilitating antibodies flat help host cells linear mimicking molecular Molecular epidemiology Mutation N-terminal domain Neutralizing Neutralizing antibodies neutralizing antibody NTD omicron pandemic Retrospective analysis risk SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 strains SARS-CoV-2 variants selected spike Spike protein the SARS-CoV-2 the spike protein Vaccine Variability variable was determined [DOI] 10.3390/molecules27123851 PMC 바로가기 [Article Type] Article