secretory IgA – Page 2 – Communicable Diseases Research

Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity

인플루엔자, 백일해 및 COVID-19에 대한 예방 접종이 모유 항체에 미치는 영향: 건강 형평성에 대한 현재 증거 및 시사점

Review

Published on 2022-07-122022-09-12
Journal: Frontiers in Immunology
[Category] COVID19(2023년), MERS, SARS, 진단,

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Research article

Published on 2022-07-112022-10-05
Journal: Matter
[Category] 비임상,

Advanced Molecular and Immunological Diagnostic Methods to Detect SARS-CoV-2 Infection

Review

Published on 2022-06-102022-10-06
Journal: Microorganisms
[Category] 진단,

[키워드] adopted anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies antigen-based immunoassays antigenic appear asymptomatic individual Blood can be used China COVID-19 CRISPR death detect Diagnosis diagnostic effective ELISA globe Health care system helping immune response immunoassays increase infected with SARS-CoV-2 Infection Laboratory molecular mucosal mucosal surfaces nasal nasopharyngeal Next-generation sequencing NGS Non-invasive Oropharyngeal oropharyngeal swabs palindromic repeat PCR recent replicating virus RNA RT-PCR Saliva SARS-CoV-2 SARS-COV-2 infection secretory IgA Sensitivity and specificity Spike protein spike protein. Spread Stress subject the SARS-CoV-2 Vaccine viral antigens Viral RNA virus virus entry widespread
[DOI] 10.3390/microorganisms10061193 PMC 바로가기 [Article Type] Review

Intranasal administration of a recombinant RBD vaccine induces long-term immunity against Omicron-included SARS-CoV-2 variants

재조합 RBD 백신의 비강내 투여는 오미크론이 포함된 SARS-CoV-2 변이체에 대한 장기 면역을 유도합니다

Article

Published on 2022-05-172022-09-11
Journal: Signal Transduction and Targeted Therapy
[Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 administration booster Cell coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 deficiency demonstrated Economy effective vaccine Emergency global health Health IgG antibody immune response immune responses Immunity immunization induce intramuscularly intranasal Local long-lasting lung lymph nodes memory T cell memory T cells mice Migration mucosal mutant strain Neutralizing omicron Omicron variants outbreak persistence proliferation protective immunity RBD required respiratory robust SARS-CoV-2 SARS-CoV-2 variant secretory IgA sera Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Strains Strong suggested systemically T cells T-cell threat Vaccine vaccine candidate Vaccines variant variants waning immunity wild-type
[DOI] 10.1038/s41392-022-01002-1 PMC 바로가기 [Article Type] Article

Bacteria-enabled oral delivery of a replicon-based mRNA vaccine candidate protects against ancestral and delta variant SARS-CoV-2

레플리콘 기반 mRNA 백신 후보의 박테리아 지원 경구 전달은 조상 및 델타 변이형 SARS-CoV-2로부터 보호

Article

Published on 2022-05-042022-09-11
Journal: Molecular therapy : the journal of the American So
[Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 alphaviruses antibody antigenic diversity B.1.617.2 Bacteria Cellular immune response cellular immune responses clade contributed contributing to Coronavirus-2 COVID-19 cross-protective domain Efficacy epitope Epitopes Evolution feasible forest gene delivery hamster hamsters heptad repeat immune responses immunization immunized immunized mice Immunoglobulin lung Lungs mass vaccination membrane protein mRNA mRNA vaccine mucosal mucosal vaccine NAbs nasal Nasal cavity Neutralizing antibodies neutralizing antibody non-structural protein nsp13 offer oral Oral Immunization oral route Pneumonia principle PROTECT provide RBD Receptor binding domain recorded replicon-based respiratory Salmonella Salmonella-mediated SARS-CoV-2 secretory IgA SIgA the vaccine vaccination Vaccine vaccine efficacy variant variants variants. Viral viral replication virus
[DOI] 10.1016/j.ymthe.2022.01.042 PMC 바로가기 [Article Type] Article

The IgA in milk induced by SARS-CoV-2 infection is comprised of mainly secretory antibody that is neutralizing and highly durable over time

Research Article

Published on 2022-03-092022-10-28
Journal: PLoS ONE
[Category] COVID-19, MERS, SARS,

The seven constitutive respiratory defense barriers against SARS-CoV-2 infection

SARS-COV-2 감염에 대한 7 가지 구성 호흡기 방어 장벽

Review

Published on 2021-12-172022-09-01
Journal: Revista da Sociedade Brasileira de Medicina Tropic
[Category] SARS, 진단,

[키워드] activate adaptive Adaptive immune response adaptive immune responses airway alveoli antibodies antimicrobial peptide antimicrobial peptides Antiviral antiviral activity cascade Cell clearance component Defense Defensins and lactoferrin elicit ENhance epithelial cell Epithelial cell interferons epithelial cells functions Gas exchange IgA antibodies immune Immune cell immune cells immune responses immunomodulatory molecule Infection infectious agents Inhaled inhibit inhibit SARS-CoV-2 Innate immunity interferons Invasion lactoferrin Local luminal luminal surface mechanisms microbiota modulate Mucociliary clearance Mucus noxious overcome Particles pathogen peptides phagocytes receptor receptors regulate respiratory respiratory epithelial cells respiratory tract Respiratory tract microbiota respiratory viruses SARS-CoV-2 SARS-COV-2 infection secretory secretory IgA Seven subject surface tension Surfactant proteins tension these cell These cells Viral virus
[DOI] 10.1590/0037-8682-0461-2021 PMC 바로가기 [Article Type] Review

Secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon mRNA vaccination

Report

Published on 2021-12-022022-10-31
Journal: Cell Reports Medicine
[Category] COVID-19, SARS,

[키워드] Abstract Affect anti-RBD Anti-spike antibody antibody production Antibody titer BNT162b2 breastmilk breastmilk T cells circulating Combination Concentration controls COVID-19 cumulative determine effective evaluated Frequency functional IgA IgG immune protection immune response immune transfer induce lactating women mammary maternal vaccination memory B cell memory B cells milk-transferred SARS-CoV-2 protection milk-transferred spike-reactive T cells Moderna mRNA vaccination mRNA vaccine mRNA-1273 vaccine mucosa neutralization capacity neutralize Neutralizing neutralizing capacity occur Pfizer plasmablasts Protective RBD SARS-CoV-2 SARS-CoV-2 spike protein secretory secretory IgA SIgA spike SIgA transfer transferred vaccination
[DOI] 10.1016/j.xcrm.2021.100468 PMC 바로가기 [Article Type] Report

Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

SARS-CoV-2에 감염된 산모에게서 태어난 신생아의 면역 반응

Observational Study

Published on 2021-11-032022-09-10
Journal: JAMA Network Open
[Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] 48 hour 48 hours age antibody antibody production arbitrary unit association Birth breastmilk children Clinical outcome cohort study enrolled enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated explain exposure exposure to finding Follow-up gestational age IgA IgA antibodies IgA antibody IgG antibodies IgM antibodies IgM antibody immune complex Immune complexes immune response immune responses immune system Importance in utero Infant Infants infected with SARS-CoV-2 Infection infection with SARS-CoV-2 information investigated IQR Italy life male Maternal maternal age measure mother mucosal mucosal immune Neonatal Neonate Newborn objective occurred offspring participant parturition passive immunity Point positive Pregnancy pregnant women prospective cohort study PROTECT provided Receptor binding Receptor binding domain Relevance response Result Rome Saliva salivary SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike secretory IgA serum setting significantly higher significantly increased specific antibodies specific antibody specific IgG antibodies spike-specific antibodies Spike-specific antibody spike-specific IgG stimulate systemic immune response systemic immune responses tested transfer Transmission Umberto vertical transmission vertical virus transmission virus Virus spike virus transmission
[DOI] 10.1001/jamanetworkopen.2021.32563 PMC 바로가기 [Article Type] Observational Study

Oral Microbiome Dysbiosis Is Associated With Symptoms Severity and Local Immune/Inflammatory Response in COVID-19 Patients: A Cross-Sectional Study

Microbiology

Published on 2021-06-232022-10-31
Journal: Frontiers in Microbiology
[Category] COVID-19,

[키워드] analyzed association Bacteria clinical disease component controls coronavirus SARS-CoV-2 correlated COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients determine Dysbiosis Evidence fungi GM-CSF Gut identify IgA response IL-17 immune response Immunoglobulin Inflammation Inflammatory cytokines Local local immune response local inflammation marker microbial community Microbiome mucosal oral Oral microbiome other diseases pandemic parameter PCR primary site pro-inflammatory cytokine progression Protective quantified Replication respiratory virus response SARS-COV-2 infection secretory IgA shown significantly subjects susceptibility symptom severity symptomatic patient systemic diseases the SARS-CoV-2 therapy TNFα to define Vaccine development virus virus infection virus replication viruses WGS
[DOI] 10.3389/fmicb.2021.687513 PMC 바로가기 [Article Type] Microbiology