Serotonin – Page 2 – Communicable Diseases Research

Depressive and Neurocognitive Disorders in the Context of the Inflammatory Background of COVID-19

Review

Published on 2021-10-082022-10-29
Journal: International Review of Cell and Molecular Biology [Category] COVID-19,

Fluoxetine hydrochloride loaded lipid polymer hybrid nanoparticles showed possible efficiency against SARS-CoV-2 infection

Fluoxetine hydrochloride가 탑재된 지질 고분자 하이브리드 나노 입자는 SARS-CoV-2 감염에 대해 가능한 효율성을 보여주었습니다

Article

Published on 2021-09-252022-09-11
Journal: International journal of pharmaceutics [Category] SARS, 신약개발,

[키워드] acute respiratory syndrome coronavirus Affect Anti-inflammatory anticoagulant effects antidepressant Antiviral approach approved drug binding energy cells cellular coronavirus COVID 19 COVID-19 COVID-19 pandemic disease drug Drug repurposing drugs Economy Efficiency encapsulation ENhance fibroblast Fluoxetine Fluoxetine hydrochloride global health Health Human hydrogen Hydrogen bond Interaction Lipid Lipid polymer hybrid lung management molecular docking molecular docking studies Molecular docking study optimization Paroxetine performed Polymer predict protease repurposing respiratory SARS-COV-2 infection SARS-CoV-2 main protease selective Serotonin serotonin reuptake inhibitor severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SSRIs. suggested therapeutic activity Treatment zeta potential
[DOI] 10.1016/j.ijpharm.2021.121023 PMC 바로가기 [Article Type] Article

Recent advances in management of COVID-19: A review

Review

Published on 2021-08-272023-06-16
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] MERS, SARS,

[키워드] LPS, Lipopolysaccharides MERS, Middle East Respiratory Syndrome 1KD, Equilibrium dissociation constant (binding affinity) ADE, Antibody dependant enhancement of the disease ARDS, acute respiratory distress syndrome CDC, Centers for Disease Control and Prevention CoV, coronavirus COVID-19 COVID-19, coronavirus disease-2019 CVT, Cerebral Venous Thrombosis Dexamethasone EC50, half maximum neutralization concentration EUA, Emergency Use Authorization Famotidine FDA, Food and Drug Administration Fluoxetine fluvoxamine IC50, Half maximal inhibitory concentration IC90, Concentration that inhibits 90% of the virions ICU, Intensive care unit IL-6, interleukin 6 IMP, importin IRE1, Inositol-requiring enzyme Ivermectin melatonin monoclonal antibodies nanobodies Nbs, Nanobodies NEJM, The New England Journal of Medicine NIH, National Institutes of Health NOS, Reactive nitrogen species OTC, Over the Counter medication PCR, polymerase chain reaction RBD, receptor binding domain RdRp, RNA-dependent RNA polymerase Remdesivir ROS, reactive oxygen species S1R, Sigma 1 receptor SARS-CoV-2 SARS-CoV-2, Severe Acute Respiratory Syndrome Corona Virus 2 SARS, Severe acute respiratory syndrome sdNbs, Single domain nanobodies Serotonin SPR, surface plasmon resonance SSRI TMPRSS2, Transmembrane serine protease 2 TNF-alpha, Tumor Necrosis Factor alpha Tocilizumab WHO, World Health Organization
[DOI] 10.1016/j.biopha.2021.112107 PMC 바로가기 [Article Type] Review

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter

Article

Published on 2021-08-202022-10-04
Journal: Nature Communications [Category] 변종,

Hidden pandemic: COVID-19-related stress, SLC6A4 methylation, and infants’ temperament at 3 months

Clinical Trial

Published on 2021-08-022022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상,

[키워드] cells COVID-19 pandemic CpG DNA methylation Effect Epigenetic Human behaviour Infants longitudinal cohort study Methylation mother paediatrics predicted Pregnancy prenatal Serotonin Seven significantly SLC6A4 Stress stress-related gene trauma turn
[DOI] 10.1038/s41598-021-95053-z PMC 바로가기 [Article Type] Clinical Trial

The complicated relationships of heparin-induced thrombocytopenia and platelet factor 4 antibodies with COVID-19

헤파린 유발 혈소판 감소증과 혈소판 인자 4 항체와 코로나19의 복잡한 관계

Review

Published on 2021-08-012022-09-12
Journal: International journal of laboratory hematology [Category] MERS, SARS, 진단,

Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin

Article

Published on 2021-07-192022-10-04
Journal: Scientific Reports [Category] 신약개발,

Antiviral potential of plant polysaccharide nanoparticles actuating non-specific immunity

비특이적 면역을 작동시키는 식물 다당류 나노 입자의 항 바이러스 잠재력

Article

Published on 2021-07-012022-08-31
Journal: International journal of biological macromolecules [Category] 치료제,

Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection

SARS-CoV-2 감염에서 항염증제로서의 Fluoxetine

Article

Published on 2021-06-012022-09-11
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 유전자 메커니즘,

[키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus Admission Anti-inflammatory effects Anti-inflammatory therapy antidepressants Asthma B cell caused cell line cell lines Clinical outcome complex coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 Critical Cytokine IL6 Cytokine storm disease downstream drug Fluoxetine gp130 Hyperinflammatory response hyperinflammatory state identify IL6 IL6R IL6ST increase Infection Inflammation inflammatory pathways intensive care intensive care unit admission interact interleukin 6 knockdown mechanism Mortality NF-κB NFkB1 nuclear Nuclear factor kappa B subunit 1 Organ failure Patient potential therapy Protein receptor regulate respiratory SARS-CoV-2 SARS-COV-2 infection Selective serotonin reuptake inhibitors Sepsis Serotonin severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Signal transduction SSRIs subunit suppressed target gene transcription factor Transcription factor NF-κB. transcriptomic variety
[DOI] 10.1016/j.biopha.2021.111437 PMC 바로가기 [Article Type] Article

Drug repurposing of selective serotonin reuptake inhibitors: Could these drugs help fight COVID-19 and save lives?

선택적 세로토닌 재흡수 억제제의 약물 용도 변경: 이 약물이 COVID-19와 싸우고 생명을 구하는 데 도움이 될 수 있습니까?

Review

Published on 2021-06-012022-08-31
Journal: Journal of clinical neuroscience : official journa [Category] MERS, 신약개발, 치료제,

[키워드] 2019 novel coronavirus absence Affect Anti-inflammatory antidepressant Antidepressant drugs antiviral properties attenuate CCL-2 class clinical trials confirmed case coronavirus disease COVID-19 COVID-19 patients curative treatment Cytokines death disease drug Drug repurposing effective Emerging infectious disease Evidence Fluoxetine focus help identify IL-6 immune system immunomodulatory Infectious disease life management mental health morbidity Neurological complication Neurological complications Novel coronavirus novel coronavirus disease pandemic present pro-inflammatory Quality of life reduce reducing reported Safe SARS-CoV-2 selective Selective serotonin reuptake inhibitors (SSRIs). Serotonin serotonin reuptake inhibitor serotonin reuptake inhibitors tested therapeutic therapeutic agent therapeutic strategy TNF-α Tolerability Vaccine widespread
[DOI] 10.1016/j.jocn.2021.03.010 PMC 바로가기 [Article Type] Review