Severe respiratory distress – Page 2 – Communicable Diseases Research

An early experience of COVID-19 disease in pediatric and young adult renal transplant recipients

소아 및 젊은 성인 신장 이식 수혜자의 COVID-19 질병 초기 경험

Case Reports

Published on 2021-08-012022-09-12
Journal: Pediatric transplantation [Category] MERS, SARS, 진단,

Low PEEP Mechanical Ventilation and PaO 2 /FiO 2 Ratio Evolution in COVID-19 Patients

Covid-19

Published on 2021-07-242022-10-29
Journal: Sn Comprehensive Clinical Medicine [Category] COVID-19,

Monocytes and Macrophages in COVID-19

COVID-19의 단핵구 및 대식세포

Review

Published on 2021-07-212022-09-11
Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘,

[키워드] affected alarmin alveolar macrophage Blood caused cellular characterized clinical manifestation clinical manifestations common cold complex Consequences contagious cough COVID-19 Critical defend Defense detrimental developmental disease dominant dysfunction dysregulated effector cell exacerbating expression Fever Health heterogeneous group HLA-DR homeostasis homeostatic Host host defense hyperinflammation Infection infiltrating Inflammation Inflammatory inflammatory monocyte interferon-stimulated gene invading pathogen invading pathogens knowledge Macrophage macrophage phenotype macrophage phenotypes macrophages mammalian mechanisms mild common cold Moderate COVID-19 monocyte Monocytes mononuclear phagocyte multi-organ failure organism organs pandemic pathogen Pathogens pathological condition pathological conditions patients with moderate phagocytes phenotype plasticity pro-inflammatory cytokine pro-inflammatory cytokine release pulmonary recruited recruitment repair respiratory respiratory distress responsible resulting SARS-CoV-2 scRNA-seq severe disease Severe respiratory distress Symptoms tissue tissue damage Viral viral disease viral infection viral infections while
[DOI] 10.3389/fimmu.2021.720109 PMC 바로가기 [Article Type] Review

Clinical efficacy of Nafamostat Mesylate in combination with Favipiravir for COVID-19 pneumonia treatment review article

Review

Published on 2021-07-142022-10-04
Journal: Annals of Medicine and Surgery [Category] 신약개발, 임상, 치료법, 치료제,

[키워드] alleviation Anti-inflammatory Antibiotics Anticoagulants Antidote antivirals approach assigned Care category clinical clinical information Clinical outcome collected Combination Compound concerning condition conditions conducted coronavirus COVID COVID-19 COVID-19 infected patient COVID-19 infected patients COVID-19 patient detrimental development drug drugs Effect effective Efficacy enzyme explicit Favipiravir health condition hospital immune implication infected individuals infected patients information inhibit Inpatient intensity involved Laboratory literature review mesylate nafamostat Nafamostat mesylate novel Occurrence outcomes pathologist Patient patients Perspective Pneumonia Prevalence Probability reduce reduction Research research finding researcher responsible RNA polymerase SARS CoV-2 SARS-CoV SARS-CoV-2 SARS-CoV-2 viral Severe respiratory distress therapy Treatment utilised Vaccine viral epidemics viral strain virus strain
[DOI] 10.1016/j.amsu.2021.102560 PMC 바로가기 [Article Type] Review

Intensive care for seriously ill patients affected by novel coronavirus sars – CoV – 2: Experience of the Crema Hospital, Italy

신종 코로나바이러스 사스 감염 중환자 집중치료 - CoV - 2: 이탈리아 크레마 병원 경험

Article

Published on 2021-07-012022-09-11
Journal: The American journal of emergency medicine [Category] MERS, SARS, 진단, 치료기술, 치료제,

[키워드] 19 outbreak acute lung damage Acute respiratory infection Admission admitted to ICU Affect affected age alterations analyzed Antibiotic therapy Antiviral appear appearance ARDS assistance available data average average age barotrauma barotrauma mechanism bilateral pneumonia blood chemistry blood gas blood gas analysis Care caused cerebral hemorrhage Chest close contact Comorbidities Comorbidity Complication complications condition conditions consecutive patient cortisone CoV CoV - 2 COVID criterion Critical D-dimer death Deceased Department died disease disease outbreak distribution dosage effort Emergency emergency department emergency room Encephalitis event events Evidence experience flu forms gas analysis general condition gold heart disease help heparin heterogeneity heterogeneous high mortality Hospitalization Hydroxychloroquine hydroxychloroquine therapy hypoxia ICU identify IL6 impairment Infection intensive care intensive care unit Intubated intubated patients intubation ischemic heart disease Italy lesion lesions less liver liver failure low molecular weight lung damage majority male management Mechanical mechanical ventilation mechanism medium moderate monoclonal antibody Mortality mortality data multi-organ failure multiple comorbidities multiple comorbidity myopathies neurological New coronavirus non-invasive ventilation Novel coronavirus occurred Older onset of symptom operators outbreak oximetry pandemic parameter Pathogens pathology pathway Patient patients patients died patients with SARS phenotype Prevalence Prevention and control Prognosis Prognostic factor Protective protocol protocols recruited recruitment renal renal failure Research resource respiratory respiratory distress respiratory droplet Respiratory droplets respiratory infection respiratory insufficiency resulting SARI SARS Sepsis seriously ill patient severe hypoxia Severe respiratory distress shown sudden onset Support Surveillance survival surviving patient surviving patients survivor Survivors Symptom syndrome systemic disease the timing therapy thromboembolic thromboembolic complication tracheal Transmission Treatment venous Ventilation Viral was performed worsening
[DOI] 10.1016/j.ajem.2020.08.005 PMC 바로가기 [Article Type] Article

Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies

Article

Published on 2021-06-232022-10-29
Journal: Scientific Reports [Category] COVID-19,

[키워드] acute respiratory syndrome amino acid substitution bind comprehensive analysis conducted Consequences coronavirus Coronavirus 2019 COVID-19 COVID-19 pandemic effective vaccine functional Genetic greater hACE2 help hotspot Human human Angiotensin-converting enzyme implication infection rate information Molecular modelling Mutation natural Novel coronavirus occur outbreak pandemic Pneumonia Prophylaxis Protein Protein sequence analyses receptor reduced SARS-CoV-2 SARS-CoV-2 transmission sensitivity sequence severe disease Severe respiratory distress spike Spread Substitution the S protein the Spike therapeutic strategy unique variant variations virus Wuhan, China
[DOI] 10.1038/s41598-021-92641-x PMC 바로가기 [Article Type] Article

Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors

COVID-19 생존자의 생물학적 연령 가속 및 텔로미어 단축에 대한 증거

Hypothesis

Published on 2021-06-072022-09-10
Journal: International Journal of Molecular Sciences [Category] MERS, 바이오마커, 유전자 메커니즘,

[키워드] acceleration ACE2 ACE2 expression age age determination alteration analyzed Biological biological age characterized Cohort COVID-19 CpG cytokine death defined DeltaAge determine difficulty DIFFICULTY CONCENTRATING DNA methylation DPP-4 Dyspnea Epigenetic epigenetics fatigue fibrosis Immunosuppression increase in Inflammatory cytokine memory memory loss non-infected normality post-COVID-19 Post-COVID-19 patients PPCs pyrosequencing respiratory distress SARS-COV-2 infection Severe respiratory distress shortening sleep disorders subject survivor Survivors syndrome telomere telomeres Volunteer world population younger patient younger patients
[DOI] 10.3390/ijms22116151 PMC 바로가기 [Article Type] Hypothesis

The Role of Dysbiosis in Critically Ill Patients With COVID-19 and Acute Respiratory Distress Syndrome

Medicine

Published on 2021-06-042022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] acute respiratory distress acute respiratory syndrome Administered Alter Antibiotics ARDS causes changes in characteristic characterized clinical status coronavirus disease Coronavirus-2 COVID-19 Critical Critical care Critically ill patient distress Dysbiosis ENhance Evolution hyperinflammatory state Ill immune response Infection Inflammatory response intensive care Interaction Invasive mechanical ventilation microbiota pandemic Patient patients with COVID-19 proportions reached respiratory role SARS-CoV-2 severe COVID-19 Severe respiratory distress severity of COVID-19 Spread Support syndrome therapy with COVID-19
[DOI] 10.3389/fmed.2021.671714 PMC 바로가기 [Article Type] Medicine

Vaping Exacerbates Coronavirus-Related Pulmonary Infection in a Murine Model

Physiology

Published on 2021-05-102022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,

[키워드] beta coronavirus Contact Control coronavirus coronavirus disease Coronavirus infection COVID-19 cytokine Cytokines death described develop disease disease severity dysregulation E-cigarette Evidence exacerbate Fever global pandemic Histopathology indicate Infectious disease Inflammation intranasal less lung means measure MHV-A59 mice Mild Model Mortality outbreak pathology pulmonary pulmonary disease pulmonary inflammation Respiratory disease respiratory droplet risk factor SARS-CoV-2 Severe respiratory distress severity smoking spirometry suffered syndrome the SARS-CoV-2 therapeutic intervention Toxicity transmitted while WHO World Health Organization
[DOI] 10.3389/fphys.2021.634839 PMC 바로가기 [Article Type] Physiology

COVID-19 is associated with clinically significant weight loss and risk of malnutrition, independent of hospitalisation: A post-hoc analysis of a prospective cohort study

Observational Study

Published on 2021-04-012022-10-05
Journal: Clinical nutrition (Edinburgh, Scotland) [Category] SARS, 임상,

[키워드] Admission age alteration Analysis biochemical parameter C-reactive protein clinic clinical manifestations clinically collected Coronavirus disease 2019 Course COVID-19 COVID-19 patients demographic Department diagnosis of COVID-19 discharged home disease Emergency enrolled females Follow-up greater hospitalised hospitalised patient incidence independent initial initial body institution intensive care lost weight Malnutrition median median age multivariate logistic regression Nutritional evaluation nutritional status Outpatient Outpatient management overweight/obese Patient post-hoc analysis predicted prospective cohort study prospective observational cohort renal function risk SARS-CoV2 Severe respiratory distress Survivors systemic inflammation Treatment university Visual Analogue Scale weight weight loss were assessed
[DOI] 10.1016/j.clnu.2020.10.043 PMC 바로가기 [Article Type] Observational Study