substrate – Page 2 – Communicable Diseases Research

COVID-19 and first manic episodes: a systematic review

Review article

Published on 2022-08-012022-10-05
Journal: Psychiatry research
[Category] COVID19(2023년), SARS, 신약개발, 진단,

A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity

SARS-CoV-2 주요 프로테아제 기질 펩타이드 특이성 분석을 위한 proteomics-MM/PBSA 이중 접근법

Article

Published on 2022-08-012022-09-11
Journal: Peptides
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, 치료제,

PF-07321332 (Nirmatrelvir) does not interact with human ENT1 or ENT2: Implications for COVID-19 patients

PF-07321332(니르마트렐비르)는 인간 ENT1 또는 ENT2와 상호작용하지 않음: COVID-19 환자에 대한 시사점

Article

Published on 2022-07-012022-09-11
Journal: Clinical and translational science
[Category] COVID19(2023년), SARS, 치료제,

[키워드] acute lung injury antivirals bind Biotransformation Clinical efficacy clinical trials contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient death downregulation drug Efficacy EIDD-1931 Emergency use authorization Endothelial cell ENT ENTs expression Factor FDA food greater hypoxia in vitro inhibitor Interaction investigated lung epithelial Lung injury Lungs metabolite molnupiravir Nirmatrelvir nucleoside nucleoside analog nucleoside analogs pandemic Patient patients with COVID-19 PF-07321332 protease Protease inhibitor reflected Remdesivir Replication repression SARS-CoV-2 Severe acute respiratory syndrome shown substrate substrates the SARS-CoV-2 undergo unlikely US Food and Drug Administration viral replication Viral RNA Virology
[DOI] 10.1111/cts.13292 PMC 바로가기 [Article Type] Article

Highly Sensitive Flexible SERS-Based Sensing Platform for Detection of COVID-19

COVID-19 감지를 위한 고감도 유연한 SERS 기반 감지 플랫폼

Article

Published on 2022-06-282022-09-11
Journal: Biosensors
[Category] MERS, 바이오마커, 진단, 치료기술,

Survival of SARS-CoV-2 and bovine coronavirus on common surfaces of living environments

생활 환경의 공통 표면에서 SARS-CoV-2 및 소 코로나바이러스의 생존

Article

Published on 2022-06-232022-09-11
Journal: Scientific Reports
[Category] COVID19(2023년), SARS, 치료기술,

Magnetofluid-Integrated Multicolor Immunochip for Visual Analysis of Neutralizing Antibodies to SARS-CoV-2 Variants

SARS-CoV-2 변이체에 대한 중화 항체의 시각적 분석을 위한 자기유체 통합 다색 면역칩

Article

Published on 2022-06-142022-09-11
Journal: Analytical Chemistry
[Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제,

In silico study of substrate chemistry effect on the tethering of engineered antibodies for SARS-CoV-2 detection: Amorphous silica vs gold

SARS-CoV-2 검출을 위한 조작된 항체의 테더링에 대한 기질 화학 효과의 실리코 연구: 비정질 실리카 대 금

Article

Published on 2022-05-012022-09-11
Journal: Colloids and surfaces. B, Biointerfaces
[Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

Computer-designed repurposing of chemical wastes into drugs

Research

Published on 2022-04-272022-10-05
Journal: Nature
[Category] 신약개발,

[키워드] accelerate Algorithm analysis Comprehensive criteria Degradation drug experiment generate Giant hazards help knowledge Metrics reuse substrate tracing
[DOI] 10.1038/s41586-022-04503-9 [Article Type] Research

Biocompatible Conductive Hydrogels: Applications in the Field of Biomedicine

생체 적합성 전도성 하이드로 겔 : 생체 의학 분야의 응용

Review

Published on 2022-04-212022-08-31
Journal: International Journal of Molecular Sciences
[Category] 치료제,

In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties

특정 플라보노이드와 2019년 신종 코로나바이러스 수용체 결합 도메인의 상호작용 및 세포성 프로테아제 및 이들의 약동학적 특성에 대한 실리코 분석

Article

Published on 2022-04-012022-09-11
Journal: Journal of biomolecular structure & dynamics
[Category] COVID19(2023년), SARS, 치료제,

[키워드] 2019 2019 novel coronavirus 2019-nCoV acute respiratory syndrome coronavirus Analysis binding blood-brain barrier cathepsin B caused cellular protease cellular proteases Compound conducted coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 death drug-likeness eukaryotic cells evaluated FIVE flavonoid flavonoids gallate glycoprotein hepatotoxicity hydrogen Hydrogen bond inhibit Interaction interactions microorganism MM/PBSA molecular molecular docking molecular dynamics molecular dynamics. Molecular mechanics nCoV P-glycoprotein pharmacokinetic Protein Proteins RBD Receptor binding domain respiratory SARS-CoV-2 Serine serine protease severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike glycoprotein subgroup substrate supported surface area target proteins the receptor-binding domain TMPRSS2 Toxicity transmembrane serine protease transmembrane serine protease 2 Van
[DOI] 10.1080/07391102.2020.1840444 PMC 바로가기 [Article Type] Article