Mathematical modeling to study the impact of immigration on the dynamics of the COVID-19 pandemic: A case study for VenezuelaResearch article Published on 2022-11-012022-10-05 Journal: Spatial and spatio-temporal epidemiology [Category] SARS, 변종, [키워드] Affect affected Asymptomatic carriers basic reproduction number COVID-19 COVID-19 pandemic decrease Epidemiology Evolution FIVE identify Immigration Intervention less mathematical mathematical modeling Mild number of infected outcome pandemic parameter Perspective predict public health SARS-CoV-2 SARS-CoV-2 virus Spread susceptible the disease the SARS-CoV-2 threshold transmission rate Venezuela [DOI] 10.1016/j.sste.2022.100532 [Article Type] Research article
Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron and Other Variants in Serum From Children With Vaccination-Induced MyocarditisArticle Published on 2022-10-292022-11-15 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome children coronavirus coronavirus 2 COVID-19 healthy in both groups Infection myocarditis neutralization titer Neutralizing antibody titer omicron Other Patient receive respiratory SARS-CoV-2 significantly lower susceptible vaccination vaccination. variants [DOI] 10.1093/cid/ciac323 PMC 바로가기
Differential Infectivity of Original and Delta Variants of SARS-CoV-2 in Children Compared to AdultsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome Adults age aliquot B.1.617.2 Canada characteristic children circulating circulating SARS-CoV-2 variants coronavirus COVID-19 Culture cycle threshold Delta delta variant demographics determine dose driver implicated in viral Infection infectious titers infective Infectivity mechanism Mutation Nasopharyngeal swab nasopharyngeal swab sample original pediatric positive predominant provided RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR screened statistical analysis susceptible TCID TCID50 TCID50. tissue Transmission variant variants of concern variety Viral RNA VoC [DOI] 10.1128/spectrum.00395-22 PMC 바로가기
Multiple Introductions of SARS-CoV-2 Alpha and Delta Variants into White-Tailed Deer in PennsylvaniaArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha analyzed animal reservoir bat coronavirus coronavirus COVID-19 epidemic creating deer Delta Delta variants Epidemics example future infection genomic data help Host Human humans identify independent Infection information Lineage mammals management Multiple nasal swab North America observation occur Odocoileus Odocoileus virginianus positive replicate reported reservoir RT-qPCR SARS-CoV-2 SARS-CoV-2 pandemic significantly spike gene susceptible trajectory Transmission transmissions variant vertebrates white-tail deer white-tailed deer whole genome sequence zoonosis zoonosis. [DOI] 10.1128/mbio.02101-22 PMC 바로가기
SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial CellsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료제, [키워드] Activation Adaptive immune response association biochemical Caco2 caused changed chemokine Colon contributed COVID-19 cytokine declining Delta delta variant disease epithelial cell line evade Evolution expected fatality feature highlighting Host Human humans IFN IFN response Infection Innate innate antiviral innate immune response interferon Intervention mechanism multiple mechanism outcome pandemic pathophysiology pathway persistence receptor reduced Replication response resulting RLR pathway robust SARS-CoV-2 SARS-CoV-2 variant severe disease Severe infection severe symptom silent susceptible sustained the disease transcriptomic Treatment vaccination variant variants variants. viral evolution virulence virus with COVID-19 [DOI] 10.1128/spectrum.01604-22 PMC 바로가기
Choosing a cellular model to study SARS-CoV-2Article Published on 2022-10-212022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Antiviral compound approach Cell cell line cell lines cell model cellular China consequence Coronavirus infection COVID-19 Disadvantages experimental model growth Healthcare systems help in vitro in vitro approaches Infection Infectious disease Laboratory organoids pathogen Pathogenesis reducing Replication required Research researcher resources SARS-CoV-2 susceptible susceptible cells viral culture viral culture. viral pathogenicity virus viruses [DOI] 10.3389/fcimb.2022.1003608 PMC 바로가기
Environmental Impacts on COVID-19: Mechanisms of Increased SusceptibilityArticle Published on 2022-10-212022-11-16 Journal: Annals of Global Health [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome addition age Air pollution antioxidant benefit boost caused changes in children clinical symptom combating coronavirus COVID COVID 19 COVID-19 COVID-19 susceptibility death described disease Diseases Environment Epidemiology exposure to free radical Health host immunity host susceptibility Impact Increased induce Inflammatory cytokine storm inhibit Initially International involved knowledge less mechanism morbidity and mortality outcomes oxidative stress pediatric Preliminary data reduce respiratory tract respiratory viral infections respiratory viral infections. SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe disease severity severity of COVID-19 shown susceptibility susceptible the disease Vaccine variant viral genome viral infections viral pathogenicity while [DOI] 10.5334/aogh.3907 PMC 바로가기
COVID-19 and Gut InjuryArticle Published on 2022-10-202022-11-15 Journal: Nutrients [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 bind change children coronavirus COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients death develop disorder females GI Tract Gut high risk host cell IBD increased risk Inflammatory Inflammatory bowel disease inflammatory cell inhibitor Injury mechanism microbiota monoclonal antibody pandemic Pathologies Patient probiotics. receptor recruitment reduce Respiratory system SARS-CoV-2 secreted cytokine severe COVID-19 susceptible Symptom the disease the patient therapeutic option Viral load [DOI] 10.3390/nu14204409 PMC 바로가기
The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosisArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 24 hours activated Activation Apoptosis apoptotic cascade caused Cell cell damage characterized contribute COVID-19 CTLs Cytokines Diabetes Mellitus Diagnosis Diseases ENhance exhibit fungal Fungal infection fungi Hematological malignancies host cell Host immune response host inflammatory response host-pathogen interactions human monocyte human monocytes IL-1β IL-6 increase in individual Infection Inflammatory Inflammatory response inflammatory signaling Interaction invasive killing life-threatening modulation monocyte mortality rate Mucorales Mucormycosis NF-kB Occurrence organ pathogenic phagocyte phagocytosis priming pro-inflammatory cytokine produced progression PRRs receptor receptors receptors. regulate secreted signaling pathway spore susceptible synergistic therapy TLR TLR4 TLRs TNF-α Toll-like receptor transcription factor virulent [DOI] 10.3389/fimmu.2022.882921 PMC 바로가기
Serum angiotensin-converting enzyme 2 as a potential biomarker for SARS-CoV-2 infection and vaccine efficacyArticle Published on 2022-10-122022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] ACE2 angiotensin-converting enzyme 2 Biomarker change changes in circulating cleaved COVID-19 death declined demonstrated Disease progression dose Efficacy elevated expressing full-length highlight host cell receptor human ACE2 humans immunization increase in K18-hACE2 mice membrane mice MVA-S vaccine prevented Proteolytic processing receptor SARS-CoV-2 SARS-COV-2 infection serum serum sample serum. subsequent susceptible the SARS-CoV-2 transgenic vaccination Vaccine vaccine candidate virus virus entry [DOI] 10.3389/fimmu.2022.1001951 PMC 바로가기