Sponge Whirl-Pak Sampling Method and Droplet Digital RT-PCR Assay for Monitoring of SARS-CoV-2 on Surfaces in Public and Working Environments공공 및 작업 환경의 표면에서 SARS-CoV-2 모니터링을 위한 Sponge Whirl-Pak 샘플링 방법 및 액적 디지털 RT-PCR 분석Article Published on 2022-05-112022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Aerosols animals approach average Concentration conducted Contact Contamination contribute COVID-19 ddPCR detection rate Digital droplet droplets Environment evaluate fomites hotel increases in infection risk monitoring positive Public public transport RdRP RdRp gene real-time RT-PCR respiratory aerosol respiratory aerosols risk RT-PCR Saliva sampling SARS-CoV-2 SARS-CoV-2 detection Sponge Spread supermarket surface surfaces. swab sample swab samples targets trace Transport virus transmission working [DOI] 10.3390/ijerph19105861 PMC 바로가기 [Article Type] Article
A Pre- and Within-Pandemic Survey of SARS-CoV-2 RNA in Saliva Swabs from Stray Cats in Switzerland스위스 길 잃은 고양이의 타액 면봉에서 SARS-CoV-2 RNA에 대한 전염병 전 및 내부 조사Article Published on 2022-03-252022-09-11 Journal: Viruses [Category] SARS, 치료기술, [키워드] amplifying animal animal welfare animals approach assumption cats Chain Reaction collected Contact contact with COVID-19 COVID-19 pandemic demonstrated human-to-animal transmission humans Inconclusive investigated minor one health polymerase chain polymerase chain reaction positive Prevalence prevalent qPCR Quantitative RdRP reverse transcriptase risk RNA-dependent RNA polymerase RT-qPCR Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 RNA SARS-CoV-2 viral RNA shown species stray cats. Support survey susceptible Swab swab samples Switzerland tested transcriptase Transmission [DOI] 10.3390/v14040681 PMC 바로가기 [Article Type] Article
Plasmonic Detection of SARS-CoV-2 Spike Protein with Polymer-Stabilized Glycosylated Gold Nanorods폴리머 안정화 글리코실화 금 나노로드를 사용한 SARS-CoV-2 스파이크 단백질의 플라즈몬 검출Article Published on 2022-03-152022-09-11 Journal: ACS macro letters [Category] COVID19(2023년), SARS, 치료기술, [키워드] binding capture clinical samples Control experiment correlated correlation COVID-19 COVID-19 pandemic demonstrated detection diagnostic dose-dependent galactosamine glycan glycans glycosylated gold highlight immobilization Infection Particle Patient Polymer reducing response responses against rod SARS-CoV-2 SARS-CoV-2 spike protein selective shown spike Spike protein Surveillance swab samples the SARS-CoV-2 utility [DOI] 10.1021/acsmacrolett.1c00716 PMC 바로가기 [Article Type] Article
COVID-19 PCR test performance on samples stored at ambient temperature상온 보관 샘플에 대한 COVID-19 PCR 테스트 성능Article Published on 2022-03-012022-09-11 Journal: Journal of virological methods [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] ambient ambient temperature CDC cold chain Compliance condition coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 PCR test diagnostic ECDC Effect false-negative handling Infection Laboratory nasopharyngeal Oropharyngeal oropharyngeal samples outbreak pandemic Pandemics Patient PCR assay PCR positive positive Real-time PCR real-time PCR assay required Sample Sample storage. specimen storage storage condition swab sample swab samples temperature the WHO Transport Wuhan [DOI] 10.1016/j.jviromet.2021.114404 PMC 바로가기 [Article Type] Article
SARS-COV-2 detection in saliva and nasopharyngeal swabs using RT-PCR was similarArticle Published on 2022-03-012022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 치료기술, [키워드] collected COVID-19 detectable diagnosis of COVID-19 disease extraction Health indicated Nasopharyngeal swab nasopharyngeal swabs Negative predictive value NPs Outpatient performed Polyclinic Positive predictive value public health emergency reaction responsible RNA extraction RT-PCR Saliva saliva test SARS-CoV-2 sensitivity Sensitivity and specificity specificity Spread swab samples symptomatic the patient virus was performed widespread World Health Organization [DOI] 10.1590/0103-6440202204591 PMC 바로가기
Effect of not vortexing nasopharyngeal and throat swabs on SARS-CoV-2 nucleic acid detection: A pilot studySARS-CoV-2 핵산 검출에 대한 비인두 및 인후 면봉 검사의 효과: 파일럿 연구Article Published on 2022-03-012022-09-11 Journal: Journal of virological methods [Category] SARS, 치료기술, [키워드] Analysis appear assays automated cellular cellular material Ct values cycle threshold Effect eight IMPROVE Laboratory nasopharyngeal nucleic acid nucleic acid amplification nucleic acid tests PCR pilot study positive processing Qualitative reduction in respiratory virus Sample Sample processing SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleic acid SARS-CoV-2 RNA SARS-CoV-2 testing semi-quantitative sensitivity submitted Support Swab swab sample swab samples swabs tested throat swab transport medium Viral transport medium Vortex Vortex. Vortexing VTM while [DOI] 10.1016/j.jviromet.2022.114468 PMC 바로가기 [Article Type] Article
Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 among at-risk populations in Chiang Mai and Lamphun provinces, Thailand, during November 2020–January 20212020년 11월부터 2021년 1월까지 태국 치앙마이 및 람푼 주의 위험 인구 중 SARS-CoV-2 RNA 및 항 SARS-CoV-2의 유병률Observational Study Published on 2022-02-022022-09-12 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI Active surveillance acute respiratory syndrome acute respiratory syndrome coronavirus Analysis anti-SARS-CoV-2 antibody Asymptomatic being benefit blood sample Blood samples China conducted Confidence intervals contribute coronavirus COVID-19 cross-sectional demographic data exposure to Factor Factors help IgG IgG antibodies IgM IgM/IgG Infection Lateral flow immunoassays multivariable logistic regression Multivariable logistic regression analysis observational study outbreak participant Population positive Prevalence proportion questionnaire risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA second wave Spread susceptible swab sample swab samples symptomatic individual tested vaccination Vaccine virus was collected were used [DOI] 10.1371/journal.pone.0263127 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection감염성이 감소하고 BNT162B2 백신에 대한 감도가 다양한 SARS-COV-2 변이체가 감염 과정에서 개발됩니다.Clinical Trial Published on 2022-01-122022-08-13 Journal: PLoS Pathogens [Category] Biochemistry, 변종, 임상, 치료기술, 치료법, [키워드] addition Affect Analysis analyzed Anti-spike Antibody neutralization antibody neutralization activity Author BNT162b2 BNT162b2 vaccine circulating convalescent plasma Course COVID-19 vaccine COVID-19 vaccines demonstrated elicit employment Evolution Frequency highlight Host human host human population impair in-depth analysis increase in individual infected individual infected individuals Infection infectivity capacity intra-host SARS-CoV-2 variant intra-host SARS-CoV-2 variants Intra-host variant intra-host variants L1197I mutation landscape less low frequencies mRNA mRNA-based mutated mutated variant mutated variants N gene N genes natural infection neutralization Neutralizing antibodies nose-throat swab nose-throat swabs pandemic plasma plasma neutralization activity platform Point mutation potential circulating variants Protective Quasispecies quasispecy raised reduced respiratory Respiratory system S gene S2 subunit SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 intra-host variability SARS-CoV-2 intra-host variant SARS-CoV-2 intra-host variants SARS-CoV-2 mutagenesis SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing Sequencing database Sequencing databases single-genome sequencing Spike protein Spike proteins spike variant Spread swab sample swab samples the SARS-CoV-2 the spike protein vaccinated individuals vaccination rate variant variants variants of concern [DOI] 10.1371/journal.ppat.1010242 PMC 바로가기 [Article Type] Clinical Trial
Trajectory of Viral RNA Load Among Persons With Incident SARS-CoV-2 G614 Infection (Wuhan Strain) in Association With COVID-19 Symptom Onset and SeverityCOVID-19 증상 발병 및 중증도와 관련하여 SARS-CoV-2 G614 감염(우한 균주)이 발생한 사람의 바이러스 RNA 부하 궤적Randomized Controlled Trial Published on 2022-01-102022-09-10 Journal: JAMA Network Open [Category] 변종, 임상, 진단, 치료기술, [키워드] association Asymptomatic baseline Characteristics characterized clinical trial Clinical trial design clinical trials Cohort cohort study collected conducted correlated COVID-19 COVID-19 symptom Ct value cycle threshold Cycle threshold value Data analysis enrolled exposure finding Follow-up followed by G614 variant Importance incident individual Infection infections initial laboratory-confirmed SARS-CoV-2 infection linear load measure median median age men Mild symptom mild symptoms mixed-effects model moderate molecular natural history objective occurred Onset pandemic participant peak Person Point positive positive swab prospective cohort study public health referred to Relevance Result RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA detection SARS-CoV-2 viral SARS-CoV-2 viral load SARS-CoV-2 viral RNA SARS-CoV-2–positive sequenced sample setting severe symptom severity shedding Spread statistical model strain Swab swab sample swab samples Symptom symptom onset symptom severity symptomatic tested the patient the SARS-CoV-2 therapeutic These data trajectory Viral viral lineage Viral load Viral RNA viral shedding viral variant virus were used with COVID-19 women Wuhan Wuhan strain [DOI] 10.1001/jamanetworkopen.2021.42796 PMC 바로가기 [Article Type] Randomized Controlled Trial
Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses경증 COVID-19 환자의 바이러스 부하 해결은 선천 면역 반응 및 적응 면역 반응 모두와 관련이 있습니다Article Published on 2022-01-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 진단, 치료기술, [키워드] absence acute phase Adaptive immune response all the patients antibodies antibody Asymptomatic characterized circulating collected Comorbidities Comorbidity COVID-19 COVID-19 patient COVID-19 patients Cytokines detectable dysregulation Efficiency elevated Factor had no hospitalized COVID-19 patient Host IgG IL-1β IL-6 IL-7 IL-8 immune response implicated in viral increase in Inflammation Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators innate immune response interferon Kinetics marker mediators mild COVID-19 patient mild infection Mild symptom mild symptoms Most patient Most patients neutralize Neutralizing antibodies neutralizing antibody no increase over Patient PRNT Receptor-binding domain Resolution respiratory respiratory sample Respiratory samples Saliva saliva samples SARS-CoV-2 SARS-CoV-2 viral load SARS-CoV-2. Seroconversion serum serum samples severe COVID-19 strain swab samples Symptom T-cell activation the patient the receptor-binding domain These data TNF-α Viral Viral load Viral RNA viral RNA detection virus isolate Virus neutralization [DOI] 10.1016/j.jcv.2021.105060 PMC 바로가기 [Article Type] Article