A switching dynamic model based on phased COVID-19 data in Chongqing and its evaluationResearch article Published on 2022-06-012022-10-05 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] China Chongqing close contact Complete Contact COVID-19 effective emergency response evaluated First-level emergency response Guidance Hospitalized implementation imported cases Invasion Isolation Local local public health Medical resources multidimensional objective quarantine reduce Reproduction number Result risk significantly switching Switching dynamic model the mean the timing was used [DOI] 10.1016/j.meegid.2022.105270 [Article Type] Research article
Perspectives on Subcutaneous Infliximab for Rheumatic Diseases and Inflammatory Bowel Disease: Before, During, and After the COVID-19 Era류마티스 질환 및 염증성 장 질환에 대한 피하 인플릭시맙의 전망: COVID-19 시대 전, 중, 후Review Published on 2022-06-012022-09-12 Journal: Advances in therapy [Category] MERS, 진단, [키워드] administration anticipated approval benefit Biobetters bowel clinical advantage clinical benefit clinical trial coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 CT-P13 SC Drug administration Efficacy and safety gastroenterology Guidance hcp healthcare Healthcare professional Healthcare system Healthcare systems IBD implementation improvement Inflammatory bowel disease infliximab Innovative biologics intravenous IV infusion management Nosocomial infection offer pandemic Patient Patient care Patient satisfaction patients Physicians Potential preference provide real-world data Real-world evidence reduced reduction in Regulatory resource rheumatic disease Rheumatic diseases rheumatoid arthritis rheumatology risk selected significant changes in Subcutaneous Subcutaneous infliximab suggested Support supported switching Telemedicine telemedicine. therapy Treatment [DOI] 10.1007/s12325-021-01990-6 PMC 바로가기 [Article Type] Review
Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus유행성, 전염병, 풍토병: B 세포 레퍼토리 분석을 통해 SARS-CoV-2, 에볼라 및 호흡기 세포융합 바이러스에 대한 독특한 항바이러스 반응이 밝혀졌습니다Article Published on 2022-05-032022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Analysis B cell Characteristics class-switch recombination (CSR) cohorts COVID-19 COVID-19 patient disease Ebola Ebolavirus Effects Endemic Epidemic event Evidence example Fever germinal centre heterogeneity humoral humoral immune response Hypothesis IgG1 IGH IGHV4-39 immature Immunity infections lack Lineage morbidity and mortality Mutation pandemic patients Recombination reflect repertoire repertoire. respiratory response risk RSV RSV (respiratory syncytial virus) SARS-CoV-2 Sequencing significant difference Support survivor switching unique vaccination Vaccine viral challenge viral infection Zaire [DOI] 10.3389/fimmu.2022.807104 PMC 바로가기 [Article Type] Article
CD8 + T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and CancerCD8 + T 세포 노화: 바이러스 감염, 자가면역 장애 및 암의 빛과 그림자Review Published on 2022-03-212022-09-11 Journal: International Journal of Molecular Sciences [Category] Coronavirus, SARS, 바이오마커, [키워드] Adaptive immune response addition Ageing Antigen Autoimmune Autoimmune disease Autoimmune diseases autoimmune disorder Autoimmune disorders Cancer cause caused CD28 CD28− CD57+ CD8+ T cells CD57 CD8 CD8+ Cell circulating clearance CMV condition contributing to cytotoxic function Diseases Effect Efficacy enrichment exacerbate favor function functions heterogeneous HIV immune-senescence immunological immunotherapies Immunotherapy implication IMPROVE Infection inflammaging inflammaging. life LIGHT low-grade inflammation lowering Lymphocytes memory Memory cells novel antigen novel antigens pathogen Pathogens phenotype Prevent progression reduction SARS-CoV-2 senescent shadow Stress switching T cell T cells T lymphocyte T lymphocytes the disease thymic Transformed cell transformed cells Tumor tumor microenvironment turn Vaccine vaccine efficacy Viral viral infection viral infections [DOI] 10.3390/ijms23063374 PMC 바로가기 [Article Type] Review
Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections Research Published on 2022-03-092022-10-05 Journal: Nature Communications [Category] 변종, 진단, [키워드] Administered Amplicon sequencing analyzed antibiotic Antibiotic resistance Antibiotic therapy Bacterial infection bacterial respiratory infection changes changes in clinically collected Cycling driving early stage Effect Evolution Frequency genomic in vivo frequency Infection isolate mechanically ventilated patient Mutation Patient Population Pseudomonas aeruginosa Rapid resistance to antibiotics respiratory infection Sequencing Sputum sample Surveillance switching therapy treated Treatment [DOI] 10.1038/s41467-022-28188-w [Article Type] Research
Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation: evidence from critically ill COVID-19 patientsObservational Study Published on 2022-03-072022-10-04 Journal: Critical Care [Category] MERS, SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome Analysis ARDS Berlin caused change COVID-19 patient criteria Critically ill Critically ill patient Evidence HFNC High-flow oxygen Hypothesis Hypoxemia ICU increase in increasingly indicate inspired oxygen fraction intensive care Invasive mechanical ventilation investigated limitation mechanical ventilation median Mild moderate nasal NIV Non-invasive Non-invasive respiratory support non-invasive ventilation oxygen pandemic PaO Patient prospective observational study provided pulmonary damage Respiratory failure Respiratory function Respiratory Support Result SARS-CoV2 severity single-center Steady state switching syndrome Uppsala University Variation ventilated patient was recorded with COVID-19 [DOI] 10.1186/s13054-022-03933-1 PMC 바로가기 [Article Type] Observational Study
Switch from Olanzapine Long-Acting Injectable to its Oral Equivalent during COVID-19 Pandemic: a Real World Observational StudyObservational Study Published on 2022-03-022022-10-04 Journal: The Psychiatric Quarterly [Category] MERS, 임상, [키워드] Administered age caused clinical Compliance conducted COVID-19 COVID-19 pandemic Diseases Effect equivalent Evolution gluteal injection intramuscular lack Long-acting antipsychotic medication NEUROLOGY Olanzapine Olanzapine pamoate oral Patient progression Psychiatric psychiatric condition Relapse Romania Schizophrenia sudden switch switching the mean the patient Treatment [DOI] 10.1007/s11126-021-09924-9 PMC 바로가기 [Article Type] Observational Study
The Role of Vitamin D in COVID-19 and the Impact of Pandemic Restrictions on Vitamin D Blood ContentPharmacology Published on 2022-02-212022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Anti-inflammatory antiviral action content COVID-19 COVID-19 infection Cytokine storm dendritic cells Evidence expected help immune system Impact indicated Infection Infectious disease Inflammatory inhibit macrophages mechanism microbial infections pandemic pro-inflammatory Th1 reduce regulate reported respiratory tract response restriction risk of COVID-19 role SARS-COV-2 infection SARS-CoV2 severe pneumonia shown Support switching Symptoms T cells Th17 Th2 Transcription treat treating SARS-CoV-2 infection Treg Vitamin D Vitamin D supplementation [DOI] 10.3389/fphar.2022.836738 PMC 바로가기 [Article Type] Pharmacology
MS-based targeted profiling of oxylipins in COVID-19: A new insight into inflammation regulationCOVID-19에서 MS 기반 옥시리핀 표적 프로파일링: 염증 조절에 대한 새로운 통찰력Observational Study Published on 2022-02-202022-09-12 Journal: Free radical biology & medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 진단, [키워드] analysed Anti-inflammatory AUC Biomarker canonical characterisation characteristic collected computation COVID-19 COVID-19 patients cytokine Cytokines dataset Fisher ICU patient ICUs Inflammation Inflammation regulation inflammation response inflammatory cascade inflammatory mediator intensive care unit Lipid lipid mediator Lipid mediator class switching magnitude Oxylipins Patient PCA pilot study plasma plasma concentration platform Pneumonia principal component analysis pro-inflammatory status Regulation respond resulting retrospective risk ROC ROC Curve selected severe COVID-19 severity predictors shown switching targeting the cytokine storm UHPLC-MS/MS. university with COVID-19 [DOI] 10.1016/j.freeradbiomed.2022.01.021 PMC 바로가기 [Article Type] Observational Study
Testing fractional doses of COVID-19 vaccines415 Published on 2022-02-072022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] accelerate approach approaches benefit booster Clinical data clinical evidence collected country COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death deaths dosage dose dose stretching doses effective Effectiveness Efficacy epidemiological Evidence expected faster fractional dosing generate Government Health high correlation Infection less lower dose much lower Neutralizing antibody response Observational data occur pandemic potential benefit public health reduce researcher severe disease Significance Support switching Testing vaccination Vaccine Vaccines while [DOI] 10.1073/pnas.2116932119 PMC 바로가기 [Article Type] 415