Response to Comment on “Tacrolimus Drug-Drug Interaction with Nirmatrelvir/Ritonavir (Paxlovid™) Managed with Phenytoin”The Poison Pen Published on 2023-03-292024-09-05 Journal: Journal of Medical Toxicology [Category] update2024, [키워드] drug-drug interaction Nirmatrelvir/ritonavir tacrolimus [DOI] 10.1007/s13181-023-00940-8 PMC 바로가기 [Article Type] The Poison Pen
A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideITarticle Published on 2023-03-222024-09-05 Journal: Trials [Category] update2024, [키워드] graft rejection immunological monitoring Immunosuppression Infection Kidney transplantation Personalised medicine tacrolimus torque teno virus [DOI] 10.1186/s13063-023-07216-0 PMC 바로가기 [Article Type] article
Cardiovascular Risk Following Conversion to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: A Randomized Clinical Trialarticle Published on 2022-11-182024-09-02 Journal: Kidney Medicine [Category] 대상포진, [키워드] Arterial stiffness belatacept blood pressure calcineurin inhibitors cardiovascular disease Kidney transplantation Mortality pulse wave velocity randomized clinical trial tacrolimus [DOI] 10.1016/j.xkme.2022.100574 PMC 바로가기 [Article Type] article
Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised groupArticle Published on 2022-10-262023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] COVID-19 mRNA vaccines Immunocompromised patients mycophenolate Sirolimus tacrolimus translation suppression. [DOI] 10.3389/fimmu.2022.1020165 PMC 바로가기
Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study류마티스 관절염 환자에서 메토트렉세이트를 배경으로 추가적인 레플루노마이드 또는 타크롤리무스와 TNF 억제제의 감염 위험: 인구 기반 코호트 연구Article Published on 2022-08-012023-06-01 Journal: Seminars in arthritis and rheumatism [Category] 대상포진, 두창, 수두, 홍역, [키워드] Infection leflunomide rheumatoid arthritis tacrolimus TNF inhibitor [DOI] 10.1016/j.semarthrit.2022.152019
Paxlovid (Nirmatelvir/Ritonavir) and Tacrolimus Drug-Drug Interaction in a Kidney Transplant Patient with SARS-2-CoV infection: A Case ReportArticle Published on 2022-07-012022-11-15 Journal: Transplantation proceedings [Category] COVID19(2023년), SARS, 치료제, [키워드] Acute kidney injury acute respiratory syndrome addition adverse effects Affect antiviral medication approved Awareness Case report Combination Community Consulting coronavirus disease dose drug-drug interaction Efficiency Emergency use enzyme health systems Immunocompromised patient Immunosuppressive medication increase induce inhibit inhibitor interactions kidney transplant medication metabolites New P450 pandemic Patient Paxlovid physician Prevent receive receiving recipient reduction rejection report risk Ritonavir robust SARS-CoV-2 serum creatinine Side effects Symptoms tacrolimus tested Transplant treat treated Treatment [DOI] 10.1016/j.transproceed.2022.04.015 PMC 바로가기
The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture사이클로필린 의존성 칼시뉴린 억제제 보클로스포린은 세포 배양에서 SARS-CoV-2 복제를 억제합니다Article Published on 2022-06-242022-09-11 Journal: Transplant International [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity Antiviral assays assays benefit binding calcineurin calcineurin inhibitors can not clinical evaluation CNI Combination Comorbidity Compound compounds Concentration coronavirus Coronaviruses Course COVID-19 cyclophilin cyclosporin cyclosporin A EC50 value EC50 values evaluated experiments False-positive results human Calu-3 cell human Calu-3 cells Immunosuppressant immunosuppressants Immunosuppression immunosuppressive increased risk Infection inhibitor Interference kidney kidney transplant recipients Kidney transplantation lab progeny protocol recipient reduced reducing regimen reported RNA viruses SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus tacrolimus voclosporin voclosporin. with COVID-19 [DOI] 10.3389/ti.2022.10369 PMC 바로가기 [Article Type] Article
Combination therapy of tacrolimus, high doses of glucocorticosteroids, and cyclophosphamide against existing historical treatment for patients in severe conditions of interstitial lung diseases complicated with dermatomyositis A retrospective analysis4000 Published on 2022-06-172024-09-04 Journal: Medicine [Category] 대상포진, [키워드] calcineurin inhibitor dermatomyositis Glucocorticosteroid immunosuppressive agent Interstitial lung diseases Methylprednisolone Prednisolone tacrolimus [DOI] 10.1097/MD.0000000000029108 PMC 바로가기 [Article Type] 4000
A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19시스템 생물학 접근 방식으로 COVID-19 중증 환자의 사망률을 줄이기 위한 후보 약물 식별Article Published on 2022-06-032022-09-11 Journal: Science Advances [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus applied approach attribute candidate candidate drug caused coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 Critically ill Critically ill patient critically ill patients drug target drug treatment effective Epigenetic Hospital admission host response identify interferon interferon signaling lack Messenger RNA metabolism monocyte Mortality Nintedanib Ordinal Scale pathway Pathways Patient patients hospitalized reduce mortality RNA splicing SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severely ill patient severely ill patients Systems biology tacrolimus therapeutic transcriptomic Treatment Vaccines with COVID-19 Zotatifin [DOI] 10.1126/sciadv.abm2510 PMC 바로가기 [Article Type] Article
Assessment of humoral and cellular immune responses to SARS CoV-2 vaccination (BNT162b2) in immunocompromised renal allograft recipients면역 저하된 신장 동종이식 환자에서 SARS CoV-2 백신(BNT162b2)에 대한 체액 및 세포 면역 반응 평가Article Published on 2022-04-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence Allograft Assessing assessment belatacept BNT162b2 booster vaccinations both groups CD4+ CD8+ T-cell Cellular immune response controls Critical cytomegalovirus deficiencies demonstrated dose Efficacy examined healthy controls humoral IgG IgG response IgG responses immune immune response immune responses Immunocompromised immunosuppressive in both group individual Infection ISP kidney kidney transplant limit memory MMF mycophenolate mycophenolate mofetil no differences of BNT162b2 partial immunity Patient patients peptide peptides Pfizer Prednisone preventing infection protective immunity protocol recipient renal response responses SARS CoV-2 SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines severe deficiency severity shown spike spike IgG T-cell T-cell immunity T-cell Response T-cell responses tacrolimus vaccination Vaccine [DOI] 10.1111/tid.13813 PMC 바로가기 [Article Type] Article