tissue sample – Page 2 – Communicable Diseases Research

Influence of Aerosol Delivered BCG Vaccination on Immunological and Disease Parameters Following SARS-CoV-2 Challenge in Rhesus Macaques

히말라야 원숭이에서 SARS-CoV-2 감염 후 면역 및 질병 매개변수에 대한 에어로졸 전달 BCG 백신의 영향

Immunology

Published on 2022-02-092022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 치료기술, 치료제,

RT-PCR Testing of Organ Culture Medium for Corneal Storage Fails to Detect SARS-CoV-2 Infection Due to Lack of Viral Replication

Article

Published on 2022-01-222022-10-28
Journal: Pathogens [Category] COVID-19,

Antemortem vs Postmortem Histopathologic and Ultrastructural Findings in Paired Transbronchial Biopsy Specimens and Lung Autopsy Samples From Three Patients With Confirmed SARS-CoV-2

SARS-CoV-2가 확인된 3명의 환자로부터 한 쌍의 경기관지 생검 표본 및 폐 부검 샘플에서 사후 조직병리학적 및 미세구조적 소견 비교

Article

Published on 2022-01-062022-09-11
Journal: American journal of clinical pathology [Category] SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus alveolar alveolar damage Antemortem ARDS Autopsies Autopsy biopsy cause of death Chain Reaction change clinical evaluation Computed tomography Confirmed coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19-induced lung injury DAD death detectable died different time point different time points diffuse Diffuse alveolar damage disease enrolled fibrosis finding Fluorescence High-resolution histology Hospital admission In situ hybridization latency lung Lung fibrosis Lung injury Lung pathology one patient Organizing pneumonia pathologic Patient patients with COVID-19 performed pneumocyte Pneumonia polymerase chain polymerase chain reaction Postmortem progression reactive respiratory Respiratory failure reverse transcription reverse transcription polymerase chain reaction Sample SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen Spread TBB the disease the patient tissue sample transbronchial upper airway upper airways Vascular Viral Viral load virus widespread
[DOI] 10.1093/ajcp/aqab087 PMC 바로가기 [Article Type] Article

COVID-19 autopsy cases: detection of virus in endocrine tissues

코로나19 부검 사례: 내분비 조직에서 바이러스 검출

Article

Published on 2022-01-012022-09-11
Journal: Journal of Endocrinological Investigation [Category] MERS, SARS, 진단, 치료기술,

Extended minimally invasive autopsy: Technical improvements for the investigation of cardiopulmonary events in COVID-19

확장된 최소 침습적 부검: COVID-19의 심폐 사건 조사를 위한 기술 개선

Original Article

Published on 2021-11-172022-09-10
Journal: Clinics [Category] MERS, SARS, 치료기술,

Viral S protein histochemistry reveals few potential SARS-CoV-2 entry sites in human ocular tissues

Article

Published on 2021-09-272022-10-29
Journal: Scientific Reports [Category] COVID-19, SARS,

[키워드] ACE2 addition antibodies binding antibody auxiliary Cell Certain disease ciliary clinical evidence determine Epitopes examined expression Factor immunohistochemistry immunoreactivity increase in infect Infection infection with SARS-CoV-2 Inflammation investigated iris stroma lid low expression lung tissue margin Molecular medicine ocular performed positive positive controls Potential protein expression reported Retina reveal risk RNA RNA expression RNA sequencing RPE S protein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 receptor specimen staining supported tissue tissue sample tissues TMPRSS2 TMPRSS2 expression viral entry viral S protein was used were used while
[DOI] 10.1038/s41598-021-98709-y PMC 바로가기 [Article Type] Article

A COVID-19-association-dependent categorization of death causes in 100 autopsy cases

Original Article

Published on 2021-09-112022-11-01
Journal: GeroScience [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory syndrome age aggregate alteration alveolar fibrin analyzed association Autopsy Budapest cardiovascular disease categories category cause cause of death Central nervous system Cerebrovascular disease chronic respiratory disease Clinical management Clinical sign co-morbidity coronavirus correlation COVID-19 death defined demonstrated diabete Diffuse alveolar damage disease distribution females First wave histological abnormality Histopathology Hungary hypertension independent Infection kidney liver Liver disease lung Macrophage infiltration males malignant tumor Microscopy Mortality organ paraffin-embedded Patient performed polymerase chain reduced renal responsible SARS-CoV-2 scored second wave severity shift significantly supplementary material Symptoms tissue sample university Vascular ventilatory
[DOI] 10.1007/s11357-021-00451-w PMC 바로가기 [Article Type] Original Article

Dysbalance of ACE2 levels – a possible cause for severe COVID-19 outcome in COPD

ACE2 수준의 불균형 - COPD에서 심각한 COVID-19 결과의 가능한 원인

Article

Published on 2021-09-012022-09-11
Journal: The journal of pathology. Clinical research [Category] SARS, 유전자 메커니즘,

[키워드] ACE2 ACE2 expression ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus Analysis analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Arterial hypertension CD147 change changed changes in chronic lung disease chronic lung diseases chronic obstructive chronic obstructive pulmonary disease circulating cofactor controls COPD coronavirus Course COVID-19 datasets decrease determined by Donor downregulated elevated enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay epithelial cells expression expression levels EZR ezrin fibrosis furin Gene Expression Healthcare system Healthcare systems healthy control histological analysis hypertension infection mechanism Localization lung Lung disease lung tissue obstructive pulmonary disease outcome Patient patients plasma Plasma levels plasma samples Protective pulmonary arterial hypertension pulmonary disease pulmonary fibrosis pulmonary hypertension putative receptor quantitative PCR reduced Region risk factor Risk factors RNA sequencing sACE2 SARS-CoV-2 SARS-COV-2 infection scRNAseq Serine severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 significantly Single-cell RNA sequencing susceptibility tissue expression tissue sample tissue samples TMPRSS2 TMPRSS2 expression transmembrane serine protease transmembrane serine protease 2 viral entry virus were used
[DOI] 10.1002/cjp2.224 PMC 바로가기 [Article Type] Article

The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues

두 개의 원숭이 종에서 SARS-COV-2 감염의 급성기 후에는 폐 및 외부 조직에서 진행중인 바이러스 복제 및 병리의 징후와 관련이 있습니다.

Article

Published on 2021-08-232022-09-01
Journal: Viruses [Category] MERS, SARS, 진단, 치료기술,

[키워드] activated acute phase animal models Computed tomography Conjunctiva consequence COVID-19 cynomolgus macaque cynomolgus macaques detectable Extrapulmonary extrapulmonary tissue feces heart histological Histopathology humans immune activation Infection investigated lesion lung lung tissue Lungs Lymph node lymph nodes macaque macaques Messenger RNA necropsy NHPs non-human primates nose nose and throat phase positron emission Positron emission tomography pulmonary pulmonary lesion pulmonary lesions respiratory respiratory tract rhesus salivary salivary gland SARS-CoV-2 SARS-COV-2 infection SIGN Specy tissue sample tissue samples tomography tracheobronchial tracheobronchial lymph nodes Viral Viral RNA virus replication
[DOI] 10.3390/v13081673 PMC 바로가기 [Article Type] Article

Intravenous, Intratracheal, and Intranasal Inoculation of Swine with SARS-CoV-2

SARS-COV-2를 사용한 돼지의 정맥 내, 쇄골 내 및 비강 내 접종

Article

Published on 2021-07-302022-09-01
Journal: Viruses [Category] SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition animal model animals Antibody titer change Clinical signs collected Contact coronavirus D614G Diseases Epidemiology experiment greater group histologic Host human SARS-CoV-2 Infectious diseases inoculation intermediate hosts intranasal route intratracheal intravenous isolate Laboratory multiple coronaviruses Mutation naïve nasal/oral swab necropsy Neutralizing antibody titer New York City PCR positive pig PIGS positive rectal swab Rectal swabs reservoir reservoirs respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spread Support susceptibility susceptible swine tiger tissue sample tissue samples titers Viral viral replication virus virus isolation
[DOI] 10.3390/v13081506 PMC 바로가기 [Article Type] Article