SARS-CoV-2 Infectivity and Antibody Titer Reduction for 6 Months After Second Dose of BNT162b2 mRNA Vaccine in Health Care Workers: A Prospective Cohort Study의료 종사자에서 BNT162b2 mRNA 백신 2차 접종 후 6개월 동안 SARS-CoV-2 감염성 및 항체 역가 감소: 전향적 코호트 연구Article Published on 2022-08-122022-09-12 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody antibody formation Antibody titer antibody titer dynamics binding domain blood sample Breakthrough infection breakthrough infections Care coronavirus disease Coronavirus-2 decrease dose enrolled HCW HCWs Health Health care worker health care workers individuals Infection Infectivity Month mRNA mRNA vaccination neutralizing antibody no significant difference of BNT162b2 participant Probability Prospective receiving reduction reported SARS-CoV-2 second second vaccination titer vaccination [DOI] 10.1093/infdis/jiac035 PMC 바로가기 [Article Type] Article
Evidence of Maternal Antibodies Elicited by COVID-19 Vaccination in Amniotic Fluid: Report of Two Cases in Italy양수에서 COVID-19 백신 접종으로 유도된 모체 항체의 증거: 이탈리아의 2건의 사례 보고Case Reports Published on 2022-07-212022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] administration amniotic Amniotic fluid Antenatal anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibodies antibody Birth center collected COVID-19 COVID-19 vaccination Critical cross Efficiency elicited evidence of fetus gestation high risk highlighting IgG immunization Infant Infants Infectious disease Infectious diseases Italy Kinetics Maternal mechanism Newborn offer outcomes passive immunity persistence Placenta Pregnancy pregnant women prevention regimens report response to vaccination SARS-COV-2 infection second dose serum severe disease tested titer titers transfer vaccination women [DOI] 10.3390/v14071592 PMC 바로가기 [Article Type] Case Reports
Seroprevalence and dynamics of anti-SARS-CoV-2 antibodies: a longitudinal study based on patients with underlying diseases in Wuhan항-SARS-CoV-2 항체의 혈청유병률 및 역학: 우한의 기저 질환 환자를 기반으로 한 종단 연구Article Published on 2022-07-152022-09-11 Journal: Respiratory Research [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] 95% CI All participant All participants anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antibody titer Assessing asymptomatic patient asymptomatic patients baseline Blood blood sample Blood samples change Community COVID-19 Diseases door effective family members feature Follow-up Government healthcare Households Humoral immunity IgA IgG IgG antibodies IgG antibody IgG titer IgG titers IgM immunoglobulins individual infected with SARS-CoV-2 list Local local government natural infection Neutralising Antibodies neutralising antibody Neutralizing antibody titer no significant difference nucleocapsid protein participant Participants Patient positive Prevention and control Protein provided questionnaire Randomly remained Research SARS-CoV-2 SARS-CoV-2 nucleocapsid selected serological Seroprevalence serum sample serum samples significantly Single natural infection symptomatic patient Symptomatic patients telephone tested titer total antibodies total antibody underlying disease underlying diseases venous venous blood was collected were assessed Wuhan [DOI] 10.1186/s12931-022-02096-5 PMC 바로가기 [Article Type] Article
Use of Tumor Necrosis Factor-α Antagonists Is Associated With Attenuated IgG Antibody Response Against SARS-CoV-2 in Vaccinated Patients With Inflammatory Bowel Disease종양 괴사 인자-α 길항제의 사용은 염증성 장 질환이 있는 백신 접종 환자에서 SARS-CoV-2에 대한 약화된 IgG 항체 반응과 관련이 있습니다Observational Study Published on 2022-07-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] Against age antagonist antagonists anti-SARS-CoV-2 antibody anti-SARS-CoV-2 vaccination antibody Antibody concentrations Antibody titer Antibody titers Biologicals Blood blood sampling bowel Characteristics clinical Clinical characteristics Combination completion Concentration COVID-19 Crohn's disease defined demonstrated detectable disease Effect elapsed geometric geometric mean IBD IgG IgG antibodies IgG antibody IgG antibody titer IgG antibody titers immune response immunoassay immunomodulating Immunosuppressive medication immunosuppressive medications increased risk independent independent of Inflammatory Inflammatory bowel disease medication Microparticle monotherapy Most patients mRNA mRNA vaccines mRNA-based vaccine mRNA-based vaccines Multivariable models Patient patient age patients patients treated prospective observational cohort quantitative determination RBD receive receiving Receptor-binding domain regimen response S1 subunit sampling SARS-CoV-2 SARS-COV-2 infection Seroconversion serological response significantly lower Spike protein the receptor-binding domain the S1 subunit the spike protein titer TNF-α-antagonists treated Treatment Tumor ulcerative colitis vaccination Vaccine vector was used were measured were recorded [DOI] 10.3389/fimmu.2022.920333 PMC 바로가기 [Article Type] Observational Study
Changes in SARS-CoV-2 Antibody Titers from Three to Nine Months after Administration of the BNT162b2 mRNA Vaccine among Healthcare Workers in Japan: A Prospective Study일본 의료 종사자의 BNT162b2 mRNA 백신 투여 후 3개월에서 9개월로 SARS-CoV-2 항체가의 변화: 전향적 연구Article Published on 2022-07-012022-09-12 Journal: Internal medicine (Tokyo, Japan) [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Abstract BNT162b2 mRNA change healthcare Healthcare workers Japan Month Prospective SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody titer titer Vaccine worker [DOI] 10.2169/internalmedicine.9695-22 PMC 바로가기 [Article Type] Article
Evaluation of commercial Anti-SARS-CoV-2 neutralizing antibody assays in seropositive subjects혈청 양성 환자에서 상업용 Anti-SARS-CoV-2 중화 항체 분석 평가Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] absence added addition anti-RBD Anti-RBD antibodies Anti-RBD antibody anti-spike antibody anti-Spike IgG antibody Antibody titer Area bioMérieux cells cellular receptor Commercial tests Competitive anti-RBD immunoassays correlation difficulty functional highlight house immunoassay immunoassays immunochromatographic test Interaction marker NAb titer NAb titers neutralization test Neutralizing antibodies neutralizing antibody neutralizing antibody assay New P-value patients plaque reduction neutralization PRNT qualitative test Quantitative reduction SARS-CoV-2 SARS-CoV-2 entry Sensitivity and specificity sera seropositive subject seropositive subjects Spike protein surrogate surrogate markers Surrogate markers of protection. sVNT tested the spike protein threshold thresholds titer variants of concern virus neutralization test VNT VoC [DOI] 10.1016/j.jcv.2022.105169 PMC 바로가기 [Article Type] Article
Antibody Titers After a Third and Fourth SARS-CoV-2 BNT162b2 Vaccine Dose in Older Adults노인에서 세 번째 및 네 번째 SARS-CoV-2 BNT162b2 백신 투여 후 항체 역가Article Published on 2022-07-012022-09-12 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Antibody titer cohort study dose evaluate Immunoglobulin individual Older SARS-CoV-2 BNT162b2 titer vaccine dose [DOI] 10.1001/jamanetworkopen.2022.23090 PMC 바로가기 [Article Type] Article
Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms임신 3개월 및 플랫폼 전반에 걸친 COVID-19 백신 접종 후 모체 면역 반응 및 태반 항체 전달Article Published on 2022-06-282022-09-11 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Activation Ad26 Ad26.COV2.S Analysis antibody antibody transfer BNT162b2 cellular complement Cord blood COVID-19 vaccination COVID-19 vaccine deposition evaluate function functions humoral immune response immune response Immunity individual Maternal maternal antibody mRNA mRNA vaccination mRNA vaccine mRNA vaccines mRNA-1273 Neonatal neutrophil NK-cell phagocytosis placental platform Pregnancy pregnant provide SARS-CoV-2 variant SARS-CoV-2 variants second trimester the United State titer transfer trimester Umbilical cord umbilical cord blood United States vaccination vaccine platform [DOI] 10.1038/s41467-022-31169-8 PMC 바로가기 [Article Type] Article
Resistance of SARS-CoV-2 Omicron BA.1 and BA.2 Variants to Vaccine-Elicited Sera and Therapeutic Monoclonal AntibodiesSARS-CoV-2 Omicron BA.1 및 BA.2 변이체의 백신 유도 혈청 및 치료용 단일클론 항체에 대한 내성Article Published on 2022-06-182022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] AstraZeneca BNT162b2 BNT162b2 vaccine COVID-19 D614G Effectiveness Emergency use fold immunization individual Lilly LY-CoV555 mixture monoclonal monoclonal antibodies monoclonal antibody monoclonal antibody therapy mutated neutralized Neutralizing titer omicron Omicron BA.2 Omicron variants parental Regeneron REGN10933 REGN10987 remained resistance SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants severe COVID-19 significantly Spike protein Spike proteins therapeutic therapy titer titers Vaccine variant variants virus [DOI] 10.3390/v14061334 PMC 바로가기 [Article Type] Article
Fcγ-Receptor-Based Enzyme-Linked Immunosorbent Assays for Sensitive, Specific, and Persistent Detection of Anti-SARS-CoV-2 Nucleocapsid Protein IgG Antibodies in Human Sera인간 혈청에서 항-SARS-CoV-2 뉴클레오캡시드 단백질 IgG 항체의 민감하고, 특이적이고, 지속적인 검출을 위한 Fcγ-수용체 기반 효소 연결 면역흡착 분석법Article Published on 2022-06-152022-09-11 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 African analytical sensitivity anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibody antibody waning Antigen antigen-antibody complexes Asia binding complexes Concentration convalescence convalescent phase coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cross-reactivity detection diagnostic diagnostic sensitivities dilutions ELISA ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays epidemiological studies Epidemiological study Europe FcγR Human IgG IgG antibody Immune complexes immunoassay immunofluorescence immunoglobulins immunological indirect immunofluorescence Infection Infectious disease Laboratory laboratory methods and tools longitudinal samples mandatory morbidity morbidity and mortality mortality rates nucleocapsid protein Pathogens persistent platform Population Postinfection Prevalence prozone receptor Region respiratory SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody sensitive sensitivity serological test Serological tests serum serum sample serum samples severe acute respiratory syndrome Coronavirus significantly significantly higher solution South America Specific Specificities specificity titer Vaccine validation Viral Viral diseases was performed while [DOI] 10.1128/jcm.00075-22 PMC 바로가기 [Article Type] Article