Evaluation of filter paper to transport oro/nasopharyngeal samples to detect SARS-CoV-2 by RT-qPCRRT-qPCR에 의한 SARS-CoV-2 검출을 위한 구강/비인두 샘플 수송을 위한 여과지의 평가Article Published on 2022-10-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] addition amplification approach carried clinical sample concentrations detect evaluate evaluated false-negative false-negative results feasible Filter Filter Paper generate impregnation Inconclusive Laboratory N1 and N2 positive result presenting qPCR reference method resource RNA extraction RT-qPCR SARS-CoV-2 SARS-CoV-2 detection specimen target Transport transportation Viral load [DOI] 10.1016/j.jviromet.2022.114587 PMC 바로가기 [Article Type] Article
Pre-analytical sample stabilization by different sampling devices for PCR-based COVID-19 diagnosticsPCR 기반 COVID-19 진단을 위한 다양한 샘플링 장치에 의한 사전 분석 샘플 안정화Article Published on 2022-09-252022-09-11 Journal: New biotechnology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Bacterial cell culture systems copy number copy numbers COVID-19 Critical detectability detectable diagnostic diagnostic testing diagnostics examined except for gold gold standard growth handling healthcare worker infectious Infectivity inhibited outbreak pandemic Patient Pre-analytic Quantitative RT-PCR reduction remained RNA RNA stability room temperature Saliva Saliva collection devices SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 RNA Sensitivity and specificity specimen specimen collection stability Swab Swab systems. temperature test results tested the SARS-CoV-2 Transport Viral Viral RNA [DOI] 10.1016/j.nbt.2022.04.001 PMC 바로가기 [Article Type] Article
Substantial impact of mobility restrictions on reducing COVID-19 incidence in Italy in 2020Article Published on 2022-09-172022-11-16 Journal: Journal of Travel Medicine [Category] SARS, 변종, [키워드] absence accompanied adherence Admission affected benefit Cell cell phone China communicable comparable Compliance country COVID-19 COVID-19 incidence COVID-19 pandemic death decrease effective Effects Efficacy eliminated epidemic wave Epidemiology First wave had no Health highest Hospital admissions indicated Infection infections intensive care Italy linear lockdown means of transport Mobility National new SARS-CoV-2 occurred outbreak outcomes peak. reducing reduction reduction in reductions in SARS-CoV-2 Spread study period the mean threshold Transmission dynamics Transport Travel vaccine availability viral variant [DOI] 10.1093/jtm/taac081 PMC 바로가기
A systematic review of COVID-19 transport policies and mitigation strategies around the globeResearch article Published on 2022-09-012022-10-05 Journal: Transportation Research Interdisciplinary Perspectives [Category] 변종, [키워드] attribute category changes in characterized conducted Contagion country Course Coverage COVID-19 expected future work globe Government in-depth analysis literature review National offer operators Policies precursor Region Regulation reported Research risk Risks SARS-CoV-2 Strategies systematic review Transport transportation variety [DOI] 10.1016/j.trip.2022.100653 [Article Type] Research article
Potential of targeting host cell calcium dynamics to curtail SARS-CoV-2 infection and COVID-19 pathogenesisReview article Published on 2022-09-012022-10-05 Journal: Cell Calcium [Category] SARS, 신약개발, 임상, 치료제, [키워드] acting calcium Calcium signaling Clinical management clinical trial clinical trials coronavirus disease COVID-19 COVID-19 pathogenesis Critical curtail driving drug regimen Efficacy handling homeostasis host cell Host cell calcium dynamics identify impacted Infection interact management mechanisms molecular molecular mechanism pathway Potential Protein reducing Replication reported respiratory SARS-CoV-2 SARS-COV-2 infection severity Signaling signaling cascade small molecule the disease Transport vaccination [DOI] 10.1016/j.ceca.2022.102637 [Article Type] Review article
Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus MonkeysArticle Published on 2022-09-012022-11-15 Journal: Pharmaceutical research [Category] COVID19(2023년), SARS, 진단, [키워드] aerosol alternative route animal model antibodies antibody antibody concentration approach caused Clinical studies Concentration demonstrated Diseases dose epithelial lining feasibility humanized monoclonal antibody inhalation intravenous Intravenous injection lung mice Mild Moderate COVID-19 Monkey nebulized Neutralizing neutralizing antibody pharmacokinetics PRNT reached remained respiratory tract safety profile SARS-CoV-2 SARS-COV-2 infection serum shown single dose Transport treating COVID-19 was used [DOI] 10.1007/s11095-022-03340-9 PMC 바로가기
Hundreds-Dollar-Level Multiplex Integrated RT-qPCR Quantitative System for Field DetectionArticle Published on 2022-09-012022-11-15 Journal: Biosensors [Category] SARS, 치료기술, 치료제, [키워드] accelerate addition amplification applicability approach ASF characterized comparable Complete conducted COVID-19 COVID-19 pandemic crown detection diagnosing Diagnosis diagnostic disease equipment field fluorescence detection Good Health Laboratory lack low cost molecular Nucleic acid detection on-site testing Outbreaks outcomes PCR polymerase chain provide Quantitative Real-time PCR reliability RT-qPCR SARS-CoV-2 pneumonia sensitivity specificity stability System target gene Transport World Health Organization [DOI] 10.3390/bios12090706 PMC 바로가기
Rapid and accurate identification of SARS-CoV-2 Omicron variants using droplet digital PCR (RT-ddPCR)Droplet Digital PCR(RT-ddPCR)을 사용한 SARS-CoV-2 Omicron 변이체의 빠르고 정확한 식별Article Published on 2022-09-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Allelic discrimination amino acids B.1.1.529 B.1.1.529. Clinical treatment clinician Concentration confounding factor Delta described develop digital PCR Efficacy Frequency genome sequence Genome sequences genotyping identify Laboratory medium Mutation mutations NGS omicron Omicron variants positive Prevalence primer probe sequences problem professionals Protein public health Rapid reaction Receptor binding domain respiratory viruses RNA robust S-gene SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants Sensitivity and specificity shifting specimen spike Spike protein state substantial reduction substantial reductions susceptibility tested the SARS-CoV-2 therapy Transmission Transport transport medium Vaccine vaccine efficacy variant variants Variation Washington [DOI] 10.1016/j.jcv.2022.105218 PMC 바로가기 [Article Type] Article
RNA sequence analysis of nasopharyngeal swabs from asymptomatic and mildly symptomatic patients with COVID-19Research article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Analysis Asymptomatic autophagy Bacterial Cell changes in Coinfection complement COVID-19 Differential gene expression disease severity dysregulation Epigenetic gene expression profile Gene ontology group identify in both group investigated involved mildly symptomatic patient Modification modulation mRNA Nasopharyngeal swab objective outcome Patient patients performed profile progression proportion reduction in Result retrieved RNA RNA sequence SARS-CoV-2 SARS-COV-2 infection Sequence analysis Sequencing Streptococcus pneumoniae symptomatic symptomatic individuals Symptomatic patients the disease transcriptomic transcriptomics translation Transport upregulation Viral genome assembly viral variant with COVID-19 [DOI] 10.1016/j.ijid.2022.06.035 [Article Type] Research article
Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United StatesArticle Published on 2022-09-012022-11-15 Journal: Journal of veterinary diagnostic investigation : o [Category] SARS, 변종, 치료기술, [키워드] addition analyst analytical sensitivity Analytical specificity analyzed assays B.1.1.7 B.1.351 buffer COVID-19 COVID-19 pandemic Critical detect diagnosis of COVID-19 diagnostic evaluate evaluated FDA help humans identify interlaboratory comparison investigation Laboratory limitations marker medium molecular N1 and N2 network nucleocapsid pandemic public health real-time RT-PCR recognize response RNA RT-rtPCR SARS-CoV2 second specificity Support the United State Transport variant variants Viral RNA [DOI] 10.1177/10406387221115702 PMC 바로가기