Insights into the potential role of alpha1-antitrypsin in COVID-19 patients: Mechanisms, current update, and future perspectivesCOVID-19 환자에서 알파1-항트립신의 잠재적 역할에 대한 통찰력: 메커니즘, 현재 업데이트 및 미래 전망Article Published on 2021-09-012022-09-11 Journal: The clinical respiratory journal [Category] SARS, 유전자 메커니즘, [키워드] Alpha1-antitrypsin benefit caused clinical trial COVID-19 COVID-19 patients Gene therapy insight mechanism molecular Perspective Protein SARS-CoV-2 virus the SARS-CoV-2 virus treating COVID-19 patients [DOI] 10.1111/crj.13406 PMC 바로가기 [Article Type] Article
COVID-19: The Disease, the Immunological Challenges, the Treatment with Pharmaceuticals and Low-Dose Ionizing RadiationCOVID-19: 질병, 면역학적 도전, 의약품 및 저선량 전리 방사선 치료Review Published on 2021-08-272022-09-11 Journal: Cells [Category] MERS, SARS, 치료제, [키워드] alleviate Anti-inflammatory Antiviral applied cancer treatment clinical trial COVID-19 COVID-19 patients cytokine Cytokine storm death develop Dexamethasone digits disadvantage Disadvantages disease dosage Effect Effective strategies effective strategy empirical evidence Epidemiology Evidence globe health worker health workers immunological alterations life-threatening low-dose Low-dose radiotherapy motivation much lower mutations oxygen pandemic pharmaceutical Pneumonia Prevalence proliferation Radiation Registered Remdesivir SARS-CoV-2 severe COVID-19 patients Spread Symptom Symptoms the cytokine storm the disease therapeutic treating COVID-19 patients Treatment Vaccine development X-ray [DOI] 10.3390/cells10092212 PMC 바로가기 [Article Type] Review
Use of 3D printing to support COVID-19 medical supply shortages: a reviewReview Published on 2021-07-132022-10-31 Journal: Journal of 3d Printing in Medicine [Category] COVID-19, [키워드] 3D printing acute respiratory syndrome conducted coronavirus Coronavirus disease 2019 COVID-19 creating disease Epidemic health worker healthcare Healthcare system healthcare worker Hydroxychloroquine literature review Masks morbidity Mortality N95 respirator masks Novel coronavirus pandemic Patient Personal protective equipment PPE PPE, ventilators Protective Respirator Respiratory tract infections SARS-CoV-2 spread of COVID-19 Supply shortages Support three dimensional printing three-dimensional model treating COVID-19 patients ventilator [DOI] 10.2217/3dp-2020-0031 PMC 바로가기 [Article Type] Review
First molecular-based detection of SARS-CoV-2 virus in the field-collected housefliesArticle Published on 2021-07-062022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Blood conducted Diseases Fly homogenized hospital housefly Infection insect Iran Man metabolism Microbiology Molecular biology Musca domestica Pathogenesis PCR assay positive preliminary finding real-time PCR assay RNA SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 virions SARS-CoV-2 virus specimen survived tested the patient the SARS-CoV-2 the SARS-CoV-2 virus tissue sample Transmission treating COVID-19 patients virion warm Zoology [DOI] 10.1038/s41598-021-93439-7 PMC 바로가기 [Article Type] Article
Identification of Lung and Blood Microbiota Implicated in COVID-19 PrognosisArticle Published on 2021-06-102022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] Analysis Anti-inflammatory BALF Blood blood microbiota Bronchoalveolar lavage fluid contribute coronavirus Coronavirus disease 2019 correlated COVID-19 COVID-19 prognosis COVID-19 severity cytokine downregulation identification IL-4 immune immune dysregulation implication Inflammation inflammatory pathway inflammatory pathways lung Lung microbiota microbe Microbiome mononuclear cell pathway PBMC Peripheral blood Prognosis SARS-CoV-2 Signaling signaling pathway therapy tissue treating COVID-19 patients upregulation [DOI] 10.3390/cells10061452 PMC 바로가기 [Article Type] Article
Pathogenesis-based preexposure prophylaxis associated with a low risk of SARS-CoV-2 infection in healthcare workers at a designated COVID-19 hospital: a pilot studyResearch Article Published on 2021-06-072022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] ACM adverse event collected Combination conducted coronavirus disease COVID-19 defined disease effective Efficacy evaluate FIVE Frequency function functions Genetic HCW HCWs healthcare worker hospital Immunological test incidence individual Inosine ISRCTN knowledge laboratory-confirmed less low-dose medication Mild occurred Open-label outcome participant Pathogenesis pilot study positive Potassium preexposure prophylaxis PrEP Prevent Reactions Registered Research Result retrospective risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity significantly single-arm single-center study study period supplementary material Support treating COVID-19 patients treatments for COVID-19 [DOI] 10.1186/s12879-021-06241-1 PMC 바로가기 [Article Type] Research Article
Holding the frontline: a cross-sectional survey of emergency department staff well-being and psychological distress in the course of the COVID-19 outbreakResearch Article Published on 2021-05-292022-10-28 Journal: BMC health services research [Category] COVID-19, SARS, [키워드] Action Administered analyzed Care changes in cognitive conducted coronavirus coronavirus disease Course COVID-19 COVID-19 outbreak cross-sectional cross-sectional survey distress emergency department emotional equipment estimating equation facilitate fear of contamination First wave Frequency future infection healthcare professionals index intensity Likert scale limit mental health narrative Netherlands Nurse outbreak Patient Perceived stress physical Physicians protocol Psychological distress questionnaire reported Result resulting returned scored secure significantly Stress stress symptom Stressor stressors supplementary material Support Symptom the mean treating COVID-19 patients Well-being were assessed World Health Organization [DOI] 10.1186/s12913-021-06555-5 PMC 바로가기 [Article Type] Research Article
Physiological parameters of mental health predict the emergence of post-traumatic stress symptoms in physicians treating COVID-19 patients정신 건강의 생리학적 매개변수는 COVID-19 환자를 치료하는 의사의 외상 후 스트레스 증상의 출현을 예측합니다Article Published on 2021-03-152022-09-12 Journal: Translational Psychiatry [Category] SARS, 임상, 진단, 치료법, [키워드] Affect analyzed Anxiety association Biomarkers Clustering cohort study collected consequence COVID-19 COVID-19 pandemic COVID-19 patients develop examined high correlation Intervention knowledge machine machine learning measure Mental mental health Non-COVID-19 Non-COVID-19 patients pandemic parameter pattern physician physiological post-traumatic stress symptom Post-traumatic stress symptoms predict reduced reported Scientific community Sleep sleep quality subgroup susceptible traumatic stress symptoms treating COVID-19 treating COVID-19 patient treating COVID-19 patients Treatment strategies Work environment [DOI] 10.1038/s41398-021-01299-6 PMC 바로가기 [Article Type] Article
Assessing the knowledge, attitude and perception on workplace readiness regarding COVID-19 among health care providers in Ethiopia—An internet-based surveyResearch Article Published on 2021-03-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affected Assessing average Care conducted COVID COVID patient COVID-19 disease disease transmission Factor handling hcp Health Improving Infection information investigated knowledge majority measure MOST Novel coronavirus objective pandemic Personal protective equipment Perspective PPE protocol responsible Result Safe treating COVID-19 patients working [DOI] 10.1371/journal.pone.0247848 PMC 바로가기 [Article Type] Research Article
Assessment of dispersion of airborne particles of oral/nasal fluid by high flow nasal cannula therapy고유량 비강 캐뉼라 요법에 의한 구강/비강액의 공기 중 입자 분산 평가Research Article Published on 2021-02-122022-08-13 Journal: PLoS ONE [Category] MERS, 임상, [키워드] Acute respiratory infection aerosol Aerosols assessment breath breathing caused Chemical clinical condition cough COVID-19 patients Cross-infection cubic deposition Detection limit distance Filter filter papers Flow greatest number greatest numbers healthy HPLC independent independent of Infection prevention liquid marker measure minute nasal nasal cannula nasal snorting NHF NHF therapy no statistically significant difference participant Participants Particle Particles Patient Prevention and control quantity Release released respiratory respiratory infection Respiratory Support Result Riboflavin riboflavin-5-monophosphate risk sneeze snort Standard statistically significant difference tested therapy treating COVID-19 patients Trial registration vigorous breathing voluntary coughing voluntary sneezing were measured were recorded [DOI] 10.1371/journal.pone.0246123 PMC 바로가기 [Article Type] Research Article