Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitorsResearch article Published on 2021-01-012022-10-05 Journal: Bioorganic & Medicinal Chemistry [Category] SARS, 신약개발, [키워드] acute respiratory syndrome Anti-viral anti-viral drug caused Combination Compound coronavirus COVID-19 disease drug candidate Drug discovery effective effort enzyme inhibitor insight low molecular weight mental health MPro Non-covalent inhibitor Papain-like protease parameter pharmacokinetic physical PLPro protease Protease activity Protease inhibitor protease inhibitors provide reported SARS-CoV-2 selective Structure-activity relationship (SAR) target unavailability viral replication [DOI] 10.1016/j.bmc.2020.115860 [Article Type] Research article
An overview of the effect of bioaerosol size in coronavirus disease 2019 transmission코로나바이러스 질병 2019 전염에서 바이오에어로졸 크기의 영향 개요Review Published on 2020-12-082022-08-31 Journal: The International Journal of Health Planning and M [Category] MERS, SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerodynamic size affecting bioaerosol by mouth contaminated surfaces coronavirus coronavirus disease Coronavirus disease 2019 coughing COVID‐19 COVID‐19 decision disease distance exposure to eye eyes Government healthy Host Immunological response Infection measure mortality rate mouth nose other persons Particle Particles path pathogen pathogenic public health reduce respiratory respiratory tract RNA copies RNA copy SARS‐CoV‐2 SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus sneezing social distancing Spread submicron Transmission Treatment unavailability Vaccine Validity virus [DOI] 10.1002/hpm.3095 PMC 바로가기 [Article Type] Review
Potential of electric stimulation for the management of COVID-19COVID-19 관리를 위한 전기 자극의 가능성Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 치료제, [키워드] adjuvant antiviral drugs approved boost immunity clinically COVID-19 COVID-19 pandemic drug effective Electric stimulation Evidence functions globe growth health emergency Human Hypothesis Immunity IMPROVE inhibit SARS-CoV-2 management outcome Pain pandemic penetration Potential reduce Research respiratory Respiratory function Respiratory function. respiratory functions significantly symptomatic symptomatic therapies the disease therapeutic therapeutic options therapy Till Treatment treatment regimen unavailability Vaccine [DOI] 10.1016/j.mehy.2020.110259 PMC 바로가기 [Article Type] Article
Evaluation of COVID-19 Surveillance Strategy in Ecuador에콰도르의 코로나19 감시 전략 평가Brief Report Published on 2020-09-092022-09-10 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] addition affecting applied Asymptomatic Behavior carried confirmed case confirmed cases coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 test COVID-19 tests detection diagnostic test diagnostic tests Ecuador examined Government growth Iceland Measures Mild positive Probability Public public health South Korea Strategy symptomatic symptomatic patient Symptomatic patients the disease the epidemic theorem Transmission unavailability [DOI] 10.1017/dmp.2020.326 PMC 바로가기 [Article Type] Brief Report