Interrupted Time Series Analysis of Pediatric Infectious Diseases and the Consumption of Antibiotics in an Atlantic European Region during the SARS-CoV-2 PandemicArticle Published on 2022-02-182022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] administrative record age Algorithm Analysis analyzed antibacterial agents Antibiotics applied Area ATC automatically Bacterial cephalosporins changes in Chemical classification Consumption decrease dose drug utilization Effect Epidemiology European Health identify incidence individuals Infection Infectious disease Infectious diseases Interrupted Interrupted time series analysis measure mechanism medication Observational data pandemic Pandemics pediatric primary care provided quantified real-world data reduce reduction in Region Regression model SARS-CoV-2 Sery significantly Spain the SARS-CoV-2 therapeutic time transmitted urinary tract infections use of antibiotics Vigo World Health Organization’ [DOI] 10.3390/antibiotics11020264 PMC 바로가기 [Article Type] Article
Reduced dispensing of prescribed antibiotics during the Covid-19 pandemic has not increased severe complications from common infectionsCovid-19 Pandemic 동안 처방 된 항생제의 분배 감소는 일반적인 감염으로 인한 심각한 합병증을 증가시키지 않았습니다.Research Published on 2022-02-082022-09-10 Journal: BMC Public Health [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료기술, 치료제, [키워드] accelerated Admission Admissions age antibiotic Antibiotics Bacterial infection Bacterial infections Care Complication COVID-19 COVID-19 pandemic decrease drug group Hospital admission Hospital admissions incidence increase in Infection infections Infectious complications mitigate open otitis Outpatient outpatients pandemic pharmacies Pharmacy Pneumonia prescription Prescriptions reached recommendation remained respiratory respiratory infection respiratory infections Respiratory tract infections Result return severe complication severe complications sinusitis skin infections supplementary material Swedish tonsillitis Treatment urinary tract infection urinary tract infections [DOI] 10.1186/s12889-022-12692-1 PMC 바로가기 [Article Type] Research
Emphysematous cystitis with bilateral pyelonephritis in a pediatric patient with COVID-19Case Reports Published on 2022-02-032023-07-08 Journal: BMJ case reports [Category] COVID19(2023년), [키워드] COVID-19 gas/free gas urinary tract infections [DOI] 10.1136/bcr-2021-245779 PMC 바로가기 [Article Type] Case Reports
Time series analysis of the incidence of acute upper respiratory tract infections, COVID-19 and the use of antibiotics in Finland during the COVID-19 epidemic: a cohort study of 833 444 patientsCOVID-19 전염병 동안 핀란드에서 급성 상기도 감염, COVID-19 및 항생제 사용의 발생률에 대한 시계열 분석: 833,444명의 환자를 대상으로 한 코호트 연구Article Published on 2022-01-312022-09-12 Journal: BMJ Open [Category] SARS, 진단, [키워드] Analysis Antibiotics average Care Cohort cohort study COVID-19 COVID-19 case COVID-19 epidemic COVID-19 patient declined diagnose diagnosed diagnostics Epidemiology evaluate expected Finn frequencies Google Health Service healthcare Healthcare professional help incidence increase in indicated Infection infections Isolation measure medical record medical service mild symptoms number outcome Patient prescription rapid increase reduced respiratory infections Spread the disease the epidemic time took place trajectory upper respiratory tract urinary tract infections URTIs use of antibiotics Variation [DOI] 10.1136/bmjopen-2020-046490 PMC 바로가기 [Article Type] Article
Emerging Roles of Vitamin D-Induced Antimicrobial Peptides in Antiviral Innate Immunity항바이러스 선천 면역에서 비타민 D 유도 항균 펩티드의 새로운 역할Review Published on 2022-01-112022-09-10 Journal: Nutrients [Category] 유전자 메커니즘, 치료제, [키워드] 25-hydroxyvitamin D active form AMP AMPs antibacterial activity antibacterial immunity antimicrobial antimicrobial peptide antimicrobial peptides antiviral immunity antiviral responses Bacterial binding calcifediol calcitriol CAMP caries Cathelicidin characterized circulating component components contribute coronavirus COVID-19 COVID-19 pandemic cytokine cytokine network Cytokines defensin Dental caries elements etiological agent Evidence Gene Expression Human immune Immune cell immune cells in vitro in vivo increased risk indication induce Infection Innate Innate immune cells Innate immunity LL-37 pathogen Pattern recognition Pattern recognition receptors peptide peptides potential mechanism potential mechanisms provided regulate role SARS-CoV2 secondary structures secretion Signaling stimulated Transcription transcription factor urinary tract infections VDR Viral Vitamin Vitamin D vitamin D deficiency Vitamin D receptor β-defensin [DOI] 10.3390/nu14020284 PMC 바로가기 [Article Type] Review
Ginger from Farmyard to Town: Nutritional and Pharmacological ApplicationsPharmacology Published on 2021-11-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] in silico molecular docking studies Zingiber officinale activity analogues Anti-inflammatory application binding affinity biological activities booster clinical trial clinical trials components Compound condition diabetes disease Effects Evidence ginger gingerols and shogaols Glycosides Health in silico Increasing indicated Inflammation Insomnia intestinal male memory Molecular docking study nausea nutritional composition obesity Pain pharmacological protective effect provide receptor protein SARS-CoV-2 Shogaol Steroids stomach ache urinary tract infections vomiting Zingiber [DOI] 10.3389/fphar.2021.779352 PMC 바로가기 [Article Type] Pharmacology
Future Trends in Semiconducting Gas-Selective Sensing Probes for Skin Diagnostics피부 진단을 위한 반도체 가스 선택적 감지 프로브의 미래 동향Perspective Published on 2021-11-132022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] acetone alcohols ammonia Asthma Biomarker Biomarkers blood stream bowel Breast breath can be used cancers carbon monoxide cholesterol chronic obstructive chronic obstructive pulmonary disease Colitis Colon Compound conditions cystic fibrosis diabete diabetes diagnostics disease Diseases effective fibrosis flu Focusing Future gastrointestinal tract heart disease ICU Patients include Infection Infectious diseases irritable bowel syndrome isoprene life lung Metabolic diseases monitoring Nanotechnology Neurological diseases nitric oxide obesity obstructive pulmonary disease pancreatic Pneumonia pulmonary diseases Quality of life skin skin gas sleep apnea syndrome the disease trend unique urinary tract infections variety [DOI] 10.3390/s21227554 PMC 바로가기 [Article Type] Perspective
Bordetella hinzii Pneumonia and Bacteremia in a Patient with SARS-CoV-2 InfectionDispatch Published on 2021-11-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, [키워드] acute respiratory syndrome Bacteremia Bacteria Bacterial Bordetella Bordetella hinzii Cholangitis coccobacilli coronavirus coronavirus disease COVID-19 Endocarditis Immunocompromised patients Infection Patient Pneumonia reported respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Soft tissue infections urinary tract infections zoonoses [DOI] 10.3201/eid2711.211468 PMC 바로가기 [Article Type] Dispatch
K 2P 18.1 translates T cell receptor signals into thymic regulatory T cell developmentArticle Published on 2021-10-262022-10-04 Journal: Cell Research [Category] 신약개발, [키워드] Activation Autoimmune Autoimmunity Calcium signalling cell fate Clinical outcome developmental disorders dominant-negative driving expression facilitated gain-of-function identify in vitro in vivo increase in intracellular calcium Ion channel signalling Loss lymphoproliferative mice Mild Missense modulated modulation multiple sclerosis Mutation NF-κB Patient phenotype potassium channel provided reduced Regulatory Regulatory T cell selection process sustained T cell T cell receptor TCR therapeutic thymic thymic emigrant thymocyte transcription factor translate Treg upregulation urinary tract infections variant [DOI] 10.1038/s41422-021-00580-z PMC 바로가기 [Article Type] Article
Multifaceted antibiotic stewardship intervention using a participatory-action-research approach to improve antibiotic prescribing for urinary tract infections in frail elderly (ImpresU): study protocol for a European qualitative study followed by a pragmatic cluster randomised controlled trial연약한 노인 (IMPRESU)의 요로 감염에 대한 항생제 처방을 개선하기 위해 참여 적 행동-연구 접근법을 사용한 다면적 항생제 청지기 개입 : 유럽 정 성적 연구를위한 연구 프로토콜과 실용적인 군집 무작위 통제 시험에 대한 연구 프로토콜General practice / Family practice Published on 2021-10-072022-09-10 Journal: BMJ Open [Category] Fulltext, MERS, SARS, 임상, [키워드] Analysis antibiotic antibiotic use Antibiotics approach asymptomatic bacteriuria bacteriuria baseline Care Cluster complex concerning contributing to control group Controlled trial COVID-19 Data collection develop dissemination effective Ethical approval ethical committee ethical committees Ethics European expected Factor follow-up period followed by General practitioners heterogeneous implementation IMPROVE Intervention intervention group medical education & training Netherlands non-specific Norway Patient peer-reviewed Poland practitioners Pragmatic Prescriptions primary care Primary outcome promote randomised controlled trial receive recruit reduce registration number restrictiveness Study protocol supported Symptom urinary tract infection urinary tract infections UTI [DOI] 10.1136/bmjopen-2021-052552 PMC 바로가기 [Article Type] General practice / Family practice