A novel assessment method for COVID-19 humoral immunity duration using serial measurements in naturally infected and vaccinated subjectsArticle Published on 2022-09-292022-11-15 Journal: PLoS ONE [Category] SARS, 변종, 진단, [키워드] antibodies antibody Antigen applied Characteristics Collecting COVID-19 defined determine Dilution dilutions dose doses help humoral Humoral immunity immune response Infection information intensity linear long-lasting MONITOR Pfizer Prevent profile protective immunity quantification quantitative assay RBD reactivity Reinfection Sample SARS-CoV-2 SARS-CoV-2 antigens serological serology test serum sample subject two group vaccination Vaccination strategies Vaccine variant Viral antigen was used were used [DOI] 10.1371/journal.pone.0274553 PMC 바로가기
Comparative analysis of the neutralizing activity against SARS-CoV-2 Wuhan-Hu-1 strain and variants of concern: Performance evaluation of a pseudovirus-based neutralization assayArticle Published on 2022-09-262022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] Ad26.COV2.S Affect analyzed anti-SARS-CoV-2 AZD1222 B.1.1.529 B.1.617.2 booster dose booster vaccination BSL-2 collected Comparative analysis condition controls convalescent correlated COVID-19 Delta Efficacy elicited emergence gold standard help helping Immune status immunogenicity individual Infection live viruses management MNT mRNA mRNA-1273 NAb neutralization neutralization activity Neutralization assay neutralize Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron performance pseudotyped Pseudotyped virus receiving reduced reduction reliability SARS-CoV-2 SARS-CoV-2 spike protein second dose sera strain vaccination Vaccination strategies Vaccine vaccinee Vaccines variant variants of concern variants of SARS-CoV-2 Viral vector virus VoC VOCs were used wild type WT strain Wuhan-Hu-1 [DOI] 10.3389/fimmu.2022.981693 PMC 바로가기
Assessing COVID-19 vaccination strategies in varied demographics using an individual-based modelArticle Published on 2022-09-152022-11-15 Journal: Frontiers in Public Health [Category] SARS, 변종, 치료기술, 치료제, [키워드] age agent-based model (ABM) applied Assessing asymptomatic infections booster doses Characteristics Contact COVID COVID- 19 COVID-19 COVID-19 vaccination COVID-19 vaccine demographics distribution distributions Effectiveness Efficiency help Hospitalization household size individual individual-base model Infection infection rate Intervention New non-pharmaceutical interventions (NPIs) NPI NPIs outbreak parameter Prevent Probability reproductive responses against SARS-CoV-2 severe disease structures subpopulation symptomatic Total unique vaccinate vaccination Vaccination strategies Vaccination strategy variants variants of SARS-CoV-2 [DOI] 10.3389/fpubh.2022.966756 PMC 바로가기
Strategic COVID-19 vaccine distribution can simultaneously elevate social utility and equity Research Published on 2022-08-252022-10-05 Journal: Nature human behaviour [Category] 치료법, [키워드] association balancing Community complex COVID-19 COVID-19 pandemic COVID-19 vaccine Critical distribution Epidemic equity evaluate example feature Health heterogeneous less provide risk utility Vaccination strategies Vaccine [DOI] 10.1038/s41562-022-01429-0 [Article Type] Research
The Effect of Gestational Age at BNT162b2 mRNA Vaccination on Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody LevelsBNT162b2 mRNA 백신 접종 시 재태 연령이 산모 및 신생아 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 항체 수준에 미치는 영향Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome age Antenatal anti-S antibody antibody level antibody transfer antibody waning benefit Blood BNT162b2 mRNA booster dose Care collected coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 early gestation Effect evaluated Evaluating highest IgG level immunization implication infancy Level lowest Maternal mRNA vaccination Neonatal parturient Pregnancy Receptor binding domain respiratory SARS-CoV-2 SARS-CoV-2 BNT162b2 SARS-CoV-2 spike protein sera serology severe disease significantly higher vaccination Vaccination strategies Vaccine vaccine dose [DOI] 10.1093/cid/ciac135 PMC 바로가기 [Article Type] Article
Advancing Precision Vaccinology by Molecular and Genomic Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 in Germany, 20212021년 독일에서 중증 급성 호흡기 증후군 코로나바이러스 2의 분자 및 게놈 감시를 통한 정밀 백신학 발전Article Published on 2022-08-152022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 유전자 메커니즘, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Advancing Alpha variant Analysis approach Beta collected complement Comprehensive contributed coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 dataset deceleration Delta wave Effectiveness effort estimate Evolution expansion facilitated Genetic genomic genomic sequencing Genomic surveillance Germany GISAID immune evasion in vitro incidence incidence estimation indicated Laboratory molecular molecular surveillance Multiple multiple mutations Mutation National neutralization assays observation period pathogen pathogen genomics Phylogenetic analysis powerful tool Precision Public public health Randomly respiratory resulting Robert Koch SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 genomic surveillance sequence sequenced sample Spread Surveillance the SARS-CoV-2 undergo vaccination Vaccination strategies Vaccination strategy Vaccine variant variant of concern variants of concern virus whole-genome sequencing [DOI] 10.1093/cid/ciac399 PMC 바로가기 [Article Type] Article
Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients향상된 SARS-CoV-2 시퀀싱 감시를 통해 감염된 환자의 새로운 변이체 및 서명 식별 가능Article Published on 2022-08-122022-09-11 Journal: Genome Medicine [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis applied approach Automation B.1 Campania cohorts of patients collected coronavirus correlated COVID-19 pandemic Disease progression Efficacy gain-of-function gene expression signature generate genetic variability Genome genomic Genomic surveillance highest Host host gene expression identify immune protection Improved increase in infected patient Infection Italy lab limit Metadata MONITOR Mutation nasal swab nasal swabs pandemic Patient premises principle producing prognostic biomarker Prognostic biomarkers reconstructed respiratory epithelium reverse transcribed RNA Sample SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-COV-2 infection SARS-CoV-2 sequencing scrutiny sequence sequenced sequences severe acute respiratory syndrome Coronavirus Spread Surveillance Transcriptome Treatment upper respiratory Vaccination strategies Vaccination strategy Variability variant variants of concern viral genome Viral genome sequencing viral genomes Viral load viral variant virus VoC was performed [DOI] 10.1186/s13073-022-01098-8 PMC 바로가기 [Article Type] Article
Benefit-risk evaluation of COVID-19 vaccination in special population groups of interest특정 인구집단에 대한 코로나19 예방접종의 유익성-위해성 평가Review Published on 2022-07-302022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] Autoimmune disease benefit-risk profile cancer diagnosis chronic inflammatory disease Course COVID-19 COVID-19 disease COVID-19 disease course COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines Efficacy effort group groups Health Health policy help HIV Human immunodeficiency virus identify Immunocompromised immunodeficiency virus include increased risk Infection kidney Kidney disease kidney or liver disease Liver disease management Mortality national health authorities oncology population groups populations recommendation SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants severe disease Special populations Transmission vaccination Vaccination strategies vaccine response vaccine responses Vaccine-induced immunity [DOI] 10.1016/j.vaccine.2022.05.067 PMC 바로가기 [Article Type] Review
Kinetics of anti-nucleocapsid IgG response in COVID-19 immunocompetent convalescent patientsCOVID-19 면역적격 회복기 환자에서 항뉴클레오캡시드 IgG 반응의 동역학Article Published on 2022-07-202022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] absence anti-Nucleocapsid IgG anti-SARS-CoV-2 anti-SARS-CoV-2 humoral antibody Antibody Response Antibody testing BMI comprehension convalescent patient Convalescent patients country COVID-19 COVID-19 convalescent patient COVID-19 disease decrease detectable develop disease severity humoral humoral immune response IgG IgG antibodies IgG antibody immunodeficiency inclusion criteria Kinetics knowledge longitudinal study majority Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nucleocapsid Patient positive Protein Re-infection robust RT- PCR SARS-CoV-2 SARS-CoV-2 nucleocapsid serum Sex Treatment Vaccination strategies Vaccination strategy virus infection [DOI] 10.1038/s41598-022-16402-0 PMC 바로가기 [Article Type] Article
Modelling the interplay of SARS-CoV-2 variants in the United Kingdom영국에서 SARS-CoV-2 변종 상호작용 모델링Article Published on 2022-07-202022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] affecting appearance applied available data compartmental model country COVID-19 COVID-19 vaccine delta variant determine Effect effective favor feature geographical distribution help include infections key factor measure pandemic parameter Prevalence prevalent Prevent recurrence SARS-CoV-2 variant severe disease Spread strain Stress the disease United Kingdom vaccination Vaccination strategies variants variants of concern [DOI] 10.1038/s41598-022-16147-w PMC 바로가기 [Article Type] Article