CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum클론 변이 GC-풍부 비암호화 RNA 가족의 CRISPR 간섭은 플라스모디움 팔시파룸에서 var 유전자의 일반적인 억제를 초래한다.Research Article Published on 2020-01-212024-08-11 Journal: mBio [Category] 말라리아, [키워드] antigenic variation epigenetics malaria parasites mutually exclusive expression ncRNA Plasmodium falciparum var genes virulence [DOI] 10.1128/mBio.03054-19 PMC 바로가기 [Article Type] Research Article
Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 VariantsArticle Published on 2019-11-132024-08-28 Journal: Cell Host & Microbe [Category] 말라리아, [키워드] antibodies Biomarker Diversity Immunity malaria PfEMP1 Plasmodium falciparum severe malaria Vaccine var genes
Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case–control study열이 없는 플라스모디움 팔시파룸 말라리아에서 var 하위 그룹과 PfSir2a 유전자의 차별적 발현: 매칭 사례-대조 연구Research Published on 2019-09-232024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] Afebrile malaria Gametocytes Mozambique PfSir2a var genes [DOI] 10.1186/s12936-019-2963-z PMC 바로가기 [Article Type] Research
Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tagPfEMP1 DBL-CIDR 헤드 구조에 대한 혈청 반응은 DBL-α 태그에 대한 반응보다 말라리아 노출의 더 나은 지표일 수 있다.Research Published on 2019-08-132024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] Immunity malaria Microarray PfEMP1 Plasmodium falciparum seroreactivity var genes [DOI] 10.1186/s12936-019-2905-9 PMC 바로가기 [Article Type] Research
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New GuineaArticle Published on 2018-07-232024-08-28 Journal: Infection and Immunity [Category] 말라리아, [키워드] antibodies DBLβ Diversity EPCR ICAM1 malaria Papua New Guinea PfEMP1 var genes
Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West AfricaArticle Published on 2017-05-162024-08-27 Journal: Microbial Cell Factories [Category] 말라리아, [키워드] Gabon parasite diversity Plasmodium falciparum strain structure var genes
Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx플라스모디움 팔시파룸의 CD36에 대한 결합은 글리코칼릭스에 의해 차단될 수 있다.Research Published on 2017-05-102024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Azido sugars cytoadhesion Endothelial glycocalyx malaria Plasmodium falciparum var genes [DOI] 10.1186/s12936-017-1844-6 PMC 바로가기 [Article Type] Research
Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria합병증이 없는 말라리아 환자와 중증 말라리아 환자에서 항체가 인식하는 PfEMP1의 차이Research Published on 2016-05-052024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] PfEMP1 severe malaria var genes [DOI] 10.1186/s12936-016-1296-4 PMC 바로가기 [Article Type] Research
Dual regulatory effects of non-coding GC-rich elements on the expression of virulence genes in malaria parasitesarticle Published on 2015-12-312024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] GC-elements malaria mutually exclusive expression non-coding RNA Plasmodium falciparum var genes [Article Type] article
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding베네인 어린이들은 EPCR 및 뇌 내피 결합과 관련된 IT4-VAR19-DC8 PfEMP1 변이에 대한 체액 면역을 개발하지 않습니다.Research Published on 2015-12-082024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] cerebral malaria endothelial protein C receptor Immunity Plasmodium falciparum Plasmodium falciparum erythrocyte membrane protein 1 var genes [DOI] 10.1186/s12936-015-1008-5 PMC 바로가기 [Article Type] Research