Automated, portable, and high-throughput fluorescence analyzer (APHF-analyzer) and lateral flow strip based on CRISPR/Cas13a for sensitive and visual detection of SARS-CoV-2SARS-CoV-2의 감도 및 시각적 검출을 위한 CRISPR/Cas13a 기반의 자동화된 휴대용 고처리량 형광 분석기(APHF 분석기) 및 측면 흐름 스트립Article Published on 2022-10-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addressed amplification automated biosensor Care Contamination coronavirus COVID-19 CRISPR CRISPR/Cas13a detect Detection limit develop globe Health Lateral lateral flow strip MOST On-site detection ORF1ab gene POCT Point point of care Point of care testing (POCT) polymerase provided recombinase polymerase amplification Recombinase polymerase amplification (RPA) RPA S gene SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus specificity Visualization [DOI] 10.1016/j.talanta.2022.123594 PMC 바로가기 [Article Type] Article
Metacells untangle large and complex single-cell transcriptome networksMetacells는 크고 복잡한 단일 세포 전사체 네트워크를 풉니다.Article Published on 2022-08-132022-09-11 Journal: BMC Bioinformatics [Category] 유전자 메커니즘, [키워드] accelerate Analysis build Cell cell type cell type annotation cells Clustering Coarse-graining complex Computational biology construction correlation COVID-19 patient COVID-19 patients demonstrated develop differential expression downstream analyses downstream analysis facilitate framework heterogeneous IMPROVE imputation inherent integration Interpretation less Metacells offer populations redundancy RNA RNA sequencing scRNA-seq scRNA-seq data significantly single-cell Single-cell RNA sequencing Single-cell transcriptomics SuperCell tissue Transcriptome transcriptomic unique Visualization [DOI] 10.1186/s12859-022-04861-1 PMC 바로가기 [Article Type] Article
Connecting omics signatures and revealing biological mechanisms with iLINCSiLINCS로 omics 서명 연결 및 생물학적 메커니즘 공개Article Published on 2022-08-092022-09-11 Journal: Nature Communications [Category] 신약개발, 유전자 메커니즘, 임상, 치료법, 치료제, [키워드] Analysis analytics bioinformatics Cancer cellular COVID 19 dataset disease facilitate iLINCS mechanism mechanism of action mTOR mTOR signaling perturbations platform programming resource transcriptomic utility Visualization web-based platform [DOI] 10.1038/s41467-022-32205-3 PMC 바로가기 [Article Type] Article
Analysis of aerosol production and aerosol dispersion during otologic surgery이비인후과 수술 중 에어로졸 생성 및 에어로졸 분산 분석Article Published on 2022-07-012022-09-11 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID19(2023년), SARS, 치료기술, [키워드] aerosol Aerosols analysed approach caused collected Concentration condition continuity coronavirus disease corpse COVID-19 deposit disease dispersion distribution droplet droplets emission healthcare personnel Horizontal plane increase information Irrigation magnification mastoidectomy material Methylene Methylene blue Microscope nasopharynx Operating room operating theatre Otologic Otologic surgery. Particle Particles performed physiological saline positive positive pressure Prevent preventive measures produced radius Respiratory disease risk surgical Transmission Viral load Visualization [DOI] 10.1007/s00405-021-07059-y PMC 바로가기 [Article Type] Article
Expediting knowledge acquisition by a web framework for Knowledge Graph Exploration and Visualization (KGEV): case studies on COVID-19 and Human Phenotype OntologyKGEV(Knowledge Graph Exploration and Visualization)용 웹 프레임워크를 통한 신속한 지식 습득: COVID-19 및 인간 표현형 온톨로지에 대한 사례 연구Article Published on 2022-06-022022-09-12 Journal: BMC Medical Informatics and Decision Making [Category] MERS, 진단, [키워드] acquisition computational method computational tool COVID-19 COVID-19 pandemic Data visualization database dataset demonstrated downstream eight emerging disease exploration facilitate filtration FIVE generate heterogenous Human human disease hypotheses information Information extraction knowledge Knowledge discovery Knowledge graph Knowledge graph. lack Metadata phenotypic question reliability Research shortest path Support utility Visualization [DOI] 10.1186/s12911-022-01848-z PMC 바로가기 [Article Type] Article
ClusTRace, a bioinformatic pipeline for analyzing clusters in virus phylogenies바이러스 계통발생의 클러스터를 분석하기 위한 생물정보학 파이프라인인 ClusTRaceArticle Published on 2022-05-282022-09-11 Journal: BMC Bioinformatics [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] accumulation aligning Analysis bioinformatic analysis clade clades Cluster cluster analysis complex coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 transmission cut down Early detection effective effort etiologic agent feature growth in-depth analysis Lineage marker mutations offer outlier Phylogenetic analysis Phylogenetic tree phylogenies Phylogeny provide public health raising Reporting SARS-CoV-2 sequence significantly super-spreading event super-spreading events Treatment treatment of COVID-19 variant Variant calling variants of SARS-CoV-2 virus Visualization [DOI] 10.1186/s12859-022-04709-8 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes중증 급성 호흡기 증후군 코로나바이러스 2 바이러스혈증은 코로나바이러스 질병 2019 심각도와 연관되어 있으며 임상 결과를 예측합니다Observational Study Published on 2022-05-032022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 진단, 치료기술, [키워드] 19 outcome 2 RNAemia 2 viremia acute respiratory syndrome acute respiratory syndrome coronavirus Admission Antibody titers bloodstream Care clinical clinical outcomes Cohort coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID COVID-19 COVID-19 patient COVID-19 severity cross-sectional discharge disease severity electron tomography hazard ratio Health Organization Hospitalized Host immune response host immune responses ICU ICU Patients immune responses immunostaining indicate Inflammatory biomarker Inpatients Level Mortality Neutralizing antibody titer neutralizing antibody titers non-ICU outcome outcomes Outpatient outpatients Patient pellet plasma plasma sample plasma samples quantified reflect respiratory SARS SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly higher Viral Viral RNA Viremia virion virions virus particle virus particles Visualization vRNA WHO World Health Organization [DOI] 10.1093/cid/ciab686 PMC 바로가기 [Article Type] Observational Study
Percutaneous dilatational tracheostomy with single use bronchoscopes versus reusable bronchoscopes – a prospective randomized trial (TraSUB)Randomized Controlled Trial Published on 2022-04-022022-10-05 Journal: BMC Anesthesiology [Category] 임상, [키워드] 1:1 Analysis Blood changes in Characteristics Contamination Cost analysis cross cross-contamination demonstrated feasible Gas exchange handling Infection introduced Likert scale Olympus Pathogens Patient Percutaneous Prevent primary end-point Randomized randomized trial risk SARS CoV-2 shown significant difference Structure the patient the primary endpoint tracheal variable Ventilation Visualization Volume were assessed [DOI] 10.1186/s12871-022-01618-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Visual Analytics for the Coronavirus COVID-19 PandemicArticle Published on 2022-04-012023-07-07 Journal: Big data [Category] COVID19(2023년), [키워드] coronavirus COVID-19 data analytics Visualization [DOI] 10.1089/big.2021.0023
Fostering compliance with physical distancing by interactive feedback in the context of the COVID-19 pandemic: A web-based randomized controlled trialResearch article Published on 2022-04-012022-10-05 Journal: Internet Interventions [Category] 임상, [키워드] Analysis Anxiety changes in Compliance conducted Containment measure control group COVID-19 Effect Evidence experiment experimental group Exploratory analysis Factor feedback Future help hygiene Infection Infectious disease information Intervention measure Measures objective pandemic participant physical distancing predicted Predictive Prevent prevention prevention of COVID-19 preventive measures Quantitative Randomized controlled trial receiving recognize reduced Result significantly higher Spread spread of COVID-19 subject tested Validity Visualization [DOI] 10.1016/j.invent.2022.100545 [Article Type] Research article