Baseline Drug Treatments as Indicators of Increased Risk of COVID-19 Mortality in Spain and Italy스페인과 이탈리아에서 Covid-19 사망률의 위험 증가를 나타내는 기준선 약물 치료Observational Study Published on 2021-11-102022-08-31 Journal: International Journal of Environmental Research an [Category] SARS, 임상, 치료제, [키워드] analyzed Antithrombotic approach baseline Campania chronic cardiovascular Clinical practice Cohort Community condition conducted COVID-19 COVID-19 patient death demographic variable diuretics drug drugs Folic acid identify Increased increased risk Indicator individual Infection Italy likelihood logistic regression models medication medications Metabolic diseases minimum Mortality observational study occur pharmacological Pharmacy Potassium profile real-world data Region Result retrospective SARS-COV-2 infection Spain systemic inflammation the disease thrombosis vitamin B12 [DOI] 10.3390/ijerph182211786 PMC 바로가기 [Article Type] Observational Study
Acute Transverse Myelitis Following COVID-19 VaccinationCase Report Published on 2021-09-102022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse effects angiotensin-converting enzyme 2 anti-SARS-CoV-2 antibody ATM Autoimmune response clinical trials Comorbidity COVID-19 COVID-19 vaccination Critical deficiency disease disorders Interaction LETM Moderna mRNA vaccine mRNA-1273 Myelitis occurred pandemic Proteins reaction receptors reported Spike protein subsequent the epidemic tissue Transverse triggered vaccination Vaccine vitamin B12 [DOI] 10.3390/vaccines9091008 PMC 바로가기 [Article Type] Case Report
Increased homocysteine mediated oxidative stress as key determinant of hepatitis E virus (HEV) infected pregnancy complication and outcome: A study from Northeast IndiaArticle Published on 2021-08-012023-06-11 Journal: Infection, genetics and evolution : journal of mol [Category] E형 간염, [키워드] Folate pathway HEV homocysteine oxidative stress pregnancy complications vitamin B12 [DOI] 10.1016/j.meegid.2021.104882
The association between micronutrient and hemogram values and prognostic factors in COVID-19 patients: A single-center experience from TurkeyObservational Study Published on 2021-06-012022-10-05 Journal: International journal of clinical practice [Category] SARS, 임상, [키워드] addition advanced age age Anemia anti-inflammatory effect antioxidant effect approach association Chronic diseases city comorbid disease Complete Concentration correlated COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients dead patients deficiencies demonstrated diagnosed with COVID-19 died disease evaluated examined excessive use folate Follow-up Gender hemoglobin hospital Hospital stay Hospitalization hypertension ICU ICU admission immune system immunomodulatory intensive care unit Intubated iron Leukocytosis lymphocyte lymphocyte counts male material men Micronutrient micronutrients multivitamin supplementation parameter Patient poor prognosis Prognostic factor Prognostic factors protective role provided respiratory tract infection retrospective significantly higher single-center the disease the mean the patient Turkey vitamin B12 vitamin D deficiency vitamin D level White blood cell worse prognosis [DOI] 10.1111/ijcp.14078 PMC 바로가기 [Article Type] Observational Study
COVID-19’s toll on the elderly and those with diabetes mellitus – Is vitamin B12 deficiency an accomplice?Research article Published on 2021-01-012022-10-05 Journal: Medical Hypotheses [Category] SARS, 신약개발, [키워드] ACEangiotensin-converting enzyme alanine aminotransferase ALTalanine aminotransferase Angiotensin-converting enzyme B12 B12Vitamin B12 BMIbody mass index body mass index C-reactive protein Case fatality rate CD4+T helper cells CD8+Cytotoxic T cells CFRCase fatality rate CIconfidence intervals complications Confidence intervals Coronavirus disease caused by SARS-CoV-2 costly COVID-19 COVID-19Coronavirus disease caused by SARS-CoV-2 CRPC-reactive protein Cytotoxic T cells deficiency diabetes Diabetes Mellitus DiabetesDiabetes mellitus eGFRestimated glomerular filtration rate Endothelial cell estimated glomerular filtration rate Evidence fatality HCVHepatitis C virus help hepatitis C virus hospitalisation Hypothesis identify IFN-γInterferon gamma ILInterleukin intensive care interferon gamma interleukin Internal ribosomal entry site for the hepatitis C virus IRESInternal ribosomal entry site for the hepatitis C virus nation National Health And Nutrition Examination Survey natural killer cell NHANESNational Health And Nutrition Examination Survey NK cellNatural killer cell Non-structural protein of SARS-CoV-2 nspNon-structural protein of SARS-CoV-2 Odds ratio OROdds Ratio outcome Patient question risk factor Safe SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SDStandard deviation severe acute respiratory syndrome coronavirus 2 significantly SOCStandard of care Standard deviation Standard of care Sustained viral response SVRSustained viral response T helper cells T2DMType-2 diabetes mellitus TNF-αTumour necrosis factor alpha Tumour necrosis factor alpha Type-2 diabetes mellitus UMFAUnmetabolized folic acid Unmetabolized folic acid Vaccine vitamin B12 [DOI] 10.1016/j.mehy.2020.110374 [Article Type] Research article
Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve StudyArticle Published on 2020-12-272023-08-30 Journal: Nutrients [Category] E형 간염, [키워드] antioxidants astaxanthin Bacopa Cognitive function Lycopene oxidative stress vitamin B12 [DOI] 10.3390/nu13010056 PMC 바로가기 [Article Type] Article
Comment on an article: “Coagulopathy in COVID-19”Comment Published on 2020-12-012023-07-12 Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, [키워드] Coagulopathy COVID-19 Folic acid homocysteine vitamin B12 [DOI] 10.1111/jth.15122 PMC 바로가기 [Article Type] Comment
Vitamin B12 may inhibit RNA-dependent-RNA polymerase activity of nsp12 from the SARS-CoV-2 virusArticle Published on 2020-10-012023-07-06 Journal: Iubmb Life [Category] SARS, [키워드] inhibitor Nsp12 RNA-dependent-RNA polymerase SARS-CoV-2 vitamin B12 [DOI] 10.1002/iub.2359 PMC 바로가기
Coronavirus Disease 2019-Related Acute Ischemic Stroke: A Case ReportInternal Medicine Published on 2020-09-082022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absence absence of risk factors Aspirin Blood cerebrovascular accident cerebrovascular accidents Chest Comorbidities complications Coronavirus disease 2019 cough COVID-19 COVID-19 pandemic crepitation CRP D-dimer diffusion diverse presentation evaluated ferritin Fever Glasgow coma scale humans hypercoagulability intensity Intervention Intubated Ischemic Ischemic Stroke Leukocytosis lower limb lung male Measures morbidity and mortality Most patient MRI neurological signs Patient patient with COVID-19 PCR performed polymerase chain positive predominant Protein raised reduce report respiratory symptoms risk factor Shortness of breath stroke the patient tomography transthoracic echocardiography TSH virus vitamin B12 weakness with COVID-19 worldwide pandemic zone [DOI] 10.7759/cureus.10310 PMC 바로가기 [Article Type] Internal Medicine
Virtual screening and repurposing of FDA approved drugs against COVID-19 main proteaseResearch article Published on 2020-06-012022-10-05 Journal: Life sciences [Category] SARS, 신약개발, 치료제, [키워드] 2019 New Coronavirus 2019-nCoV2019 New Coronavirus 3-C-like protease 3CLpro3-C-like protease acting addition Antiviral approved Comparisons Coronavirus disease 2019 CoV COVID COVID-19 COVID-19coronavirus disease 2019 CoVs dataset docking drug drugs EEnvelope envelope Epidemics FDA approved drug investigated knowledge material membrane protein MERS MERS CoVMiddle East Respiratory Syndrome Coronavirus Middle East respiratory syndrome Coronavirus Mmembrane protein MPro nicotinamide NNucleocapsid nucleocapsid open reading frames ORFopen reading frames Phylogenetic phylogenetics protease provided Research resolved ribavirin Safe SARS CoV SARSSevere Acute Respiratory Syndrome CoV sequence Severe Acute Respiratory Syndrome CoV Significance Spike protein Sspike protein systemically Treatment Virtual screening virus Vitamin vitamin B12 Wuhan, China [DOI] 10.1016/j.lfs.2020.117627 [Article Type] Research article