Age and product dependent vaccine effectiveness against SARS-CoV-2 infection and hospitalisation among adults in Norway: a national cohort study, July-November 2021Article Published on 2022-09-022022-11-16 Journal: BMC Medicine [Category] SARS, 변종, [키워드] adjusted Admissions age AZD1222 BNT162b2 booster Care change changes in Cohort studies cohort study Combination Comorbidities conditions confidence interval country covariate COVID-19 COVID-19 vaccine COVID-19 vaccines death delta variant dominant dose effective Effectiveness facilitated groups hazard heterologous schedules highest hospitalisation hospitalisations Hospitalization Infection intensive care intensive care units knowledge Mortality mRNA mRNA-1273 National Norway pandemic population-based cohort proportional hazards models provided receiving regimen regimens registries remained SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections second dose Sex Support the vaccine vaccination Vaccine vaccine dose vaccine effectiveness. waned [DOI] 10.1186/s12916-022-02480-4 PMC 바로가기
Estimation of COVID-19 mRNA Vaccine Effectiveness Against Medically Attended COVID-19 in Pregnancy During Periods of Delta and Omicron Variant Predominance in the United StatesArticle Published on 2022-09-012022-11-16 Journal: JAMA Network Open [Category] SARS, 변종, 유전자 메커니즘, [키워드] 95% CI adjusted odds ratio Against age black booster dose calculated Care case-control study conducted COVID-19 COVID-19 vaccination COVID-19 vaccine Delta delta variant dose Effectiveness eligible estimate Estimated estimation evaluate high risk Hispanic hospital Hospitalization hospitalizations IQR laboratory-confirmed molecular mRNA mRNA vaccination mRNA vaccine omicron outcome Patient Period positive Pregnancy pregnant protection SARS-CoV-2 severe COVID-19 the median the United State variant waned were excluded [DOI] 10.1001/jamanetworkopen.2022.33273 PMC 바로가기
Vaccine effectiveness against SARS-CoV-2 infection or COVID-19 hospitalization with the Alpha, Delta, or Omicron SARS-CoV-2 variant: A nationwide Danish cohort studyArticle Published on 2022-09-012022-11-16 Journal: PLoS Medicine [Category] SARS, 변종, [키워드] 95% confidence interval age Alpha variant Analysis BNT162b2 mRNA calculated CIs cohort study Comorbidity contagious coronavirus 2 COVID-19 COVID-19 hospitalization Delta delta variant Denmark dose doses Effectiveness estimate geographical region group groups Hospitalization Infection mRNA-1273 nonrandomized study Occurrence omicron provided Regression model respiratory SARS-CoV-2 SARS-COV-2 infection Sex short-lived sustained the vaccine uninfected unique vaccinated individuals vaccination Vaccination Status vaccine dose variant variants waned waning immunity was obtained was used [DOI] 10.1371/journal.pmed.1003992 PMC 바로가기
Anti-Spike Antibody Response to Natural Infection with SARS-CoV-2 and Its Activity against Emerging VariantsArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] ACE2-blocking antibody response activities activity acute infection acute respiratory syndrome acute SARS-CoV-2 infection affected angiotensin-converting enzyme 2 anti-spike antibody antibody Antibody Response average Beta Cell collected convalescent coronavirus COVID-19 detectable different time points elicited enrolled examined exhibited Fever Follow-up Frequency functional Health highlight IgM immunization Infection memory B memory B cell natural natural infection neutralization neutralization activity neutralization antibody. omicron outbreak Patient peripheral B cell Pneumonia positive reduction in reductions in response responses robust SARS-CoV-2 SARS-COV-2 infection serological serum serum sample significantly spike-specific antibody response Surveillance variant variants Viral variants waned [DOI] 10.1128/spectrum.00743-22 PMC 바로가기
Rapid Cytokine Release Assays for Analysis of Severe Acute Respiratory Syndrome Coronavirus 2-Specific T Cells in Whole Blood전혈에서 중증 급성 호흡기 증후군 코로나바이러스 2-특이적 T 세포 분석을 위한 신속한 사이토카인 방출 분석Article Published on 2022-08-242022-09-11 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed anti-receptor-binding domain antibody Blood samples characteristic clinical complicate Complication controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine cytokine Cytokine release assay diagnosed Diagnosis Diagnostic accuracy Donor EudraCT evaluated exhibited high accuracy IgG IgG levels Immunoglobulin Immunoglobulin G induction Infection interferon interferon γ memory memory response nucleocapsid Patient peptide peptides plasma Previous studies protocol Rapid receiver receiver operating characteristic Region Release remained respiratory SARS-CoV-2 seropositive serum severe acute respiratory syndrome Coronavirus Spike. stimulated study participant supernatant T cells T-cell T-cell immunity Trial vaccine doses waned Whole blood [DOI] 10.1093/infdis/jiac005 PMC 바로가기 [Article Type] Article
Antibody-Mediated Immunogenicity Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Following Priming, Boosting, and Hybrid Immunity: Insights From 11 Months of Follow-up of a Healthcare Worker Cohort in Israel, December 2020-October 2021프라이밍, 부스팅 및 하이브리드 면역에 따른 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 항체 매개 면역원성: 이스라엘 의료 종사자 집단의 11개월 추적 관찰에서 얻은 통찰력, 2020년 12월-2021년 10월Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome Against age all age group all age groups anti-S Antibody titer Breakthrough infection circulating Cohort comparable coronavirus coronavirus 2 coronavirus disease COVID-19 decrease described dose doses geometric mean concentration GMC HCW HCWs healthcare worker highlight hybrid IgG IgG level IgG levels IgG titer Immunity immunogenicity Immunoglobulin individual infected individual infected individuals Infection initial insight Israel Month participant PCR polymerase chain proportion Protective Quantitative re-infected Reinfection remained respiratory reversed S1/S2 SARS-CoV-2 subsequent tested timepoint uninfected vaccination Vaccine vaccine immunogenicity Vaccines Vaccines. waned worker [DOI] 10.1093/cid/ciac212 PMC 바로가기 [Article Type] Article
Pathogen Profile of Children Hospitalised with Severe Acute Respiratory Infections during COVID-19 Pandemic in the Free State Province, South Africa남아프리카 공화국 프리 스테이트 주에서 COVID-19 팬데믹 기간 동안 중증 급성 호흡기 감염으로 입원한 어린이의 병원체 프로필Article Published on 2022-08-212022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, 치료제, [키워드] absence Acute respiratory infection acute respiratory infections acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aetiology change children circulation Co-infection collected complicate contribute coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 transmission Ct values detection rate Diagnosis exacerbated Free Immunity infection control Influenza Influenza virus measure Mortality negativity Panel pathogen Pathogens profile QIAstat-Dx® Respiratory SARS-CoV-2 Panel respiratory respiratory infections respiratory pathogen Respiratory pathogens respiratory syncytial virus respiratory virus respiratory viruses SARI SARS-CoV-2 severe acute respiratory infections severe acute respiratory syndrome Coronavirus Severe infection severe infections South Africa state susceptibility Swab Treatment Viral detection virus waned Waves waves of COVID-19 pandemic. [DOI] 10.3390/ijerph191610418 PMC 바로가기 [Article Type] Article
Effectiveness Associated With BNT162b2 Vaccine Against Emergency Department and Urgent Care Encounters for Delta and Omicron SARS-CoV-2 Infection Among Adolescents Aged 12 to 17 Years12~17세 청소년의 Delta 및 Omicron SARS-CoV-2 감염에 대한 응급실 및 긴급 치료에 대한 BNT162b2 백신과 관련된 효과Article Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, 진단, 치료법, [키워드] 95% CI Acute respiratory infection adjusted analyses Adolescent Against age BNT162b2 booster Care case-control study Chain Reaction children conducted COVID-19 vaccine Delta delta variant Department dose doses Effectiveness Electronic health record Electronic health records Emergency emergency department encounter evaluate Health Health care Health care system help highest IQR median of BNT162b2 omicron Omicron variant Omicron variants outcome outcomes participant Polymerase chain reaction test recommendation registry data respiratory infection SARS-CoV-2 SARS-COV-2 infection tested vaccination Vaccination Status Vaccine variant variants variants of SARS-CoV-2 waned Year [DOI] 10.1001/jamanetworkopen.2022.25162 PMC 바로가기 [Article Type] Article
Characteristics associated with serological COVID-19 vaccine response and durability in an older population with significant comorbidity: the Danish Nationwide ENFORCE Study심각한 동반이환이 있는 고령 인구의 혈청학적 COVID-19 백신 반응 및 내구성과 관련된 특성: 덴마크 전국 ENFORCE 연구Article Published on 2022-08-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, [키워드] adjusted age antibody baseline ChAdOx1 Characteristics COVID-19 COVID-19 vaccination COVID-19 vaccine declined decrease defined enrolled first vaccination functional hyporesponsiveness identify IgG Immunity increasing age individual interquartile lack Level Male sex median age mRNA vaccine mRNA-1273 number of comorbidity older population outcomes parallel group participant Responder response risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination serological Sex spike vaccination. Vaccine vaccine dose vaccine response vaccine-induced antibodies vaccine-induced antibody waned were measured [DOI] 10.1016/j.cmi.2022.03.003 PMC 바로가기 [Article Type] Article
Analysis of COVID-19 Incidence and Severity Among Adults Vaccinated With 2-Dose mRNA COVID-19 or Inactivated SARS-CoV-2 Vaccines With and Without Boosters in SingaporeArticle Published on 2022-08-012022-11-16 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI adjusted Against age Assessing BBIBP-CorV BNT162b2 booster cohort study Combination combinations CoronaVac COVID-19 COVID-19 vaccination death defined determine dose Effectiveness eligible Estimated greater homologous inactivated individual Infection intensive care Moderna mRNA mRNA COVID-19 vaccine mRNA vaccine mRNA-1273 no significant difference Older omicron outcome Pfizer-BioNTech provided reduction Reinfection SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 variant severe COVID-19 severe disease Sex Singapore Sinopharm Sinovac supplemental oxygen time interval vaccination Vaccine vaccine dose waned was determined were excluded women [DOI] 10.1001/jamanetworkopen.2022.28900 PMC 바로가기